DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment jim and CG15269

DIOPT Version :9

Sequence 1:	NP_001262221.1	Gene:	jim / 43924	FlyBaseID:	FBgn0027339	Length:	938	Species:	Drosophila melanogaster
Sequence 2:	NP_609739.2	Gene:	CG15269 / 34887	FlyBaseID:	FBgn0028878	Length:	587	Species:	Drosophila melanogaster

Alignment Length:	686	Identity:	167/686 - (24%)
Similarity:	217/686 - (31%)	Gaps:	279/686 - (40%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 QDTGQPYV-LYKDSQDAERNPGAIG-----ATPAQWG--SEMYPNIQQQAQQHLTAQQQQQQQQQ 85
            |||....: |.|.|.::.|:|.|:|     :||...|  |.:.|::...|
  Fly    52 QDTSTNILDLSKSSSNSIRSPQALGGLAIPSTPYASGAYSMLPPDLVAMA--------------- 101

  Fly    86 NAAQAAAQ-------AAAVAAAAGQPQSPPGGGQEARDNGSGDGRQQQVSPSSSPYPSVQQQQRA 143
            ||.:..||       |.|.||||....:||                      :|||.:.|.||
  Fly   102 NATKFYAQFFPHLLPAYAAAAAAAGLSTPP----------------------TSPYQTHQHQQ-- 142

  Fly   144 NGAGDEDPMNHQLANQQNP--APNQNQSSNDPQHSGSNAGESGNPHVQQNGGPQNDPGNSFRTP- 205
                       .|.|||..  ||.....|..|.           |.:||...|      ..||.
  Fly   143 -----------HLPNQQKRFFAPYVINGSVPPP-----------PPLQQQQQP------LIRTKS 179

  Fly   206 ------------DYYDP------RHAAPQGGMLAPPGFPPLHYLNKGVLPME---QSGGGGGAGG 249
                        |||..      :..||    |..|....:......:.|:.   .|..||.|..
  Fly   180 TACTRPDCPECLDYYQRLQTGGYKQTAP----LISPAASSVSSSTGSIRPVRDLIMSATGGAAST 240

  Fly   250 GEAYALPEMLPAQQNGQQNAGPANTNANEGGAGANGSGG-----VGGATGASVGVGSVGVTSGGR 309
            .  .:|..:.....|..|        |...|.....:||     ||..:||..|:|....||...
  Fly   241 N--ISLTTVTNLSLNSVQ--------ATAVGMMPKMTGGLITTAVGSNSGAIGGIGGYNATSAEE 295

  Fly   310 T-----------GNGPGRPHKNKPHSDLRLFKCLTCGKDFKQKSTLLQHDRIHTDARPF--PCSE 361
            .           |.........|.|...| ::|..|||.|.|......|..:|...:.|  .|.|
  Fly   296 ISYKCRICEKVFGCSETLQAHEKTHKSPR-YECADCGKGFSQLRNYKYHLSVHRGTKEFAAECPE 359

  Fly   362 CGKRFRQQSHLTQHLRIHANEKPFTCPYCSRSFRQRAILNQHIRIHSGEKPFACPECGKHFRQKA 426
            |||.|..:.:|:.||:||.|.|.:.||||.:||.||...|.|:|||:|.||..|.||||.|.:|.
  Fly   360 CGKTFNDKGYLSSHLKIHRNRKEYECPYCPKSFNQRVAFNMHVRIHTGVKPHKCNECGKRFSRKM 424

  Fly   427 ILNQHVRTHQDVSPHLIFKNGPHPTLWPSDVPFPGEDNDTKGDIAGTGGGYHDEDSQGTPDGSGG 491
            :|.||:|||.                        ||
  Fly   425 LLKQHMRTHS------------------------GE----------------------------- 436

  Fly   492 MHYPSYFKDGKGQKILPEVLQHIGVRPANMPLYVRCPICDKEFKQKTTLLQHGCIHIESRPYPCP 556
                                                                       :||.|.
  Fly   437 -----------------------------------------------------------KPYQCS 442

  Fly   557 ECGKRFRQQSHLTQHLRIHTNEKPFGCMYCPRFFRQRTILNQHLRIHTGEKPYKCGQCGKDFRQK 621
            .|||.|..:|::|.|.|:|:..|||.|..||:.|.::..|..||..|||.|||
  Fly   443 VCGKSFADRSNMTLHHRLHSGIKPFSCPLCPKAFTKKHHLKTHLNYHTGCKPY------------ 495

  Fly   622 AILDQHTRTHQGDRPFCCPMPNCRRRFATENEVTKH 657
                            .||.|||.:.|...:.:..|
  Fly   496 ----------------VCPHPNCNQAFTQSSNMRTH 515

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
jim	NP_001262221.1	C2H2 Zn finger	331..351	CDD:275368	7/19 (37%)
		COG5048	355..666	CDD:227381	80/305 (26%)
		zf-C2H2	357..379	CDD:278523	10/23 (43%)
		C2H2 Zn finger	359..379	CDD:275368	9/19 (47%)
		zf-H2C2_2	371..396	CDD:290200	13/24 (54%)
		C2H2 Zn finger	387..407	CDD:275368	11/19 (58%)
		zf-H2C2_2	400..424	CDD:290200	14/23 (61%)
		C2H2 Zn finger	415..435	CDD:275368	11/19 (58%)
		C2H2 Zn finger	527..547	CDD:275368	0/19 (0%)
		zf-C2H2	553..575	CDD:278523	10/21 (48%)
		C2H2 Zn finger	555..575	CDD:275368	9/19 (47%)
		C2H2 Zn finger	583..603	CDD:275368	7/19 (37%)
		zf-H2C2_2	596..620	CDD:290200	9/23 (39%)
		C2H2 Zn finger	611..631	CDD:275368	0/19 (0%)
		zf-H2C2_2	624..650	CDD:290200	6/25 (24%)
		C2H2 Zn finger	639..661	CDD:275368	7/19 (37%)
CG15269	NP_609739.2	C2H2 Zn finger	300..320	CDD:275368	2/19 (11%)
		COG5048	<316..502	CDD:227381	87/326 (27%)
		C2H2 Zn finger	327..347	CDD:275368	7/19 (37%)
		zf-C2H2	356..377	CDD:278523	9/20 (45%)
		C2H2 Zn finger	357..377	CDD:275368	9/19 (47%)
		zf-H2C2_2	369..394	CDD:290200	13/24 (54%)
		C2H2 Zn finger	385..405	CDD:275368	11/19 (58%)
		zf-H2C2_2	397..422	CDD:290200	14/24 (58%)
		C2H2 Zn finger	413..433	CDD:275368	11/19 (58%)
		zf-H2C2_2	426..449	CDD:290200	14/134 (10%)
		zf-C2H2	439..461	CDD:278523	10/21 (48%)
		C2H2 Zn finger	441..461	CDD:275368	9/19 (47%)
		zf-C2H2	467..489	CDD:278523	8/21 (38%)
		C2H2 Zn finger	469..489	CDD:275368	7/19 (37%)
		C2H2 Zn finger	497..515	CDD:275368	6/17 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24384
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010