Protein Alignment jim and erm

DIOPT Version :10

• Sequence 1: NP_001262221.1
• Gene: jim / 43924
• FlyBaseID: FBgn0027339
• Length: 938
• Species: Drosophila melanogaster
• Sequence 2: NP_001259891.2
• Gene: erm / 326152
• FlyBaseID: FBgn0031375
• Length: 698
• Species: Drosophila melanogaster
• Alignment Length: 826
• Identity: 179/826 - (21%)
• Similarity: 244/826 - (29%)
• Gaps: 327/826 - (39%)

  Fly    64 PNIQQQAQQHLTAQQQQQQQQQNAAQAAAQAAAVAAAAGQPQSPPGGGQEARDNGSGDGRQQQVS 128
            |.::..|.:...|||.|||.:|:|.:|.....::|... :|                |.|..||.
  Fly    27 PVMESAASEQNPAQQSQQQDEQSAKRACPLKFSIAKIM-EP----------------DHRPSQVP 74

  Fly   129 PSSSPYPSVQQQQRANGAGDEDP------------------------------------------ 151
            |   |.|:.......:...||||
  Fly    75 P---PQPAPVSFATNDDDEDEDPEIDADSERSCSPIEVISLDQSPSTVNYDSAFKKYVPGPCSGA 136

  Fly   152 ------------------MNHQLANQQNP----APN----------------QNQSSNDPQHSGS 178
                              ..||....|.|    |||                |.||.....|..|
  Fly   137 TSSVASPPSTAAVQQFVSSRHQELLSQYPLLYYAPNQLMCAAAAAQYAALTAQQQSLASAAHLSS 201

  Fly   179 -----NAGESGNPHVQQNGGPQNDPGNSFRTPDYYDPRHAAPQGGMLAPPGFPP--LHYLNKGVL 236
                 ||....:..:::|.|               .|..||.....:|.....|  .|.|.|..:
  Fly   202 FTASLNASLHHSQSLRRNLG---------------HPLAAAAAVAAVAQSQAVPNLQHTLEKSPV 251

  Fly   237 PMEQSGGGGGAGGGEAYALPEMLPAQQNGQQNAGPANTNANEGGAGANGSGGVGGATGASVGVGS 301
            ....:...|....     |......|..|:....||:|..:..||.:......|     |:...|
  Fly   252 AQRTAQSSGLQAN-----LKRKRSPQDQGEVTPPPASTATSATGARSRSPSPQG-----SIEDSS 306

  Fly   302 VGVTSGGRTGNGPGRPHKNKPHSDLRLFKCLTCGKDFKQKSTLLQHDRIHTDARPFPCSECGKRF 366
            .|..|||            ||    :.|.||.|||.|.....|.:|..:||.||||.|..|||.|
  Fly   307 PGSASGG------------KP----KTFSCLECGKVFNAHYNLTRHMPVHTGARPFVCKVCGKGF 355

  Fly   367 RQQSHLTQHLRIHANEKPFTCPYCSRSFRQRAILNQHIRIHSGEKPFACPECGKHFRQKAILNQH 431
            ||.|.|.:|..||.:|||..|..|.::|.:.:.||.|.|||:|.|||.|..|||.|.||.....|
  Fly   356 RQASTLCRHKIIHTSEKPHKCQTCGKAFNRSSTLNTHSRIHAGYKPFVCEYCGKGFHQKGNYKNH 420

  Fly   432 VRTHQDVSPHLIFKNGPHPTLWPSDVPFPGEDNDTKGDIAGTGGGYHDEDSQGTPDGSGGMHYPS 496
            ..||                                                     ||...|
  Fly   421 KLTH-----------------------------------------------------SGEKAY-- 430

  Fly   497 YFKDGKGQKILPEVLQHIGVRPANMPLYVRCPICDKEFKQKTTLLQHGCIHIESRPYPCPECGKR 561
                                         :|.||:|.|.|...|..|...|.:.:||.|..|.|.
  Fly   431 -----------------------------KCNICNKAFHQVYNLTFHMHTHNDKKPYTCRVCAKG 466

  Fly   562 FRQQSHLTQHLR-IH---------------------TNEKPF-----------------GCMYCP 587
            |.:...|.:|:| :|                     |..:|.                 |.|..|
  Fly   467 FCRNFDLKKHMRKLHEIGGDLDDLDMPPTYDRRREYTRREPLASGYGQASGQLTPDSSSGSMSPP 531

  Fly   588 RFFRQRTILNQHLRIHTGEKPYKCGQCGKDFRQKAILDQHTR---THQ-GDRPFCCPMPNCRRRF 648
                          |:....|...|:.......::.:.|:..   .|| |..|
  Fly   532 --------------INVTTPPLSSGETSNPAWPRSAVSQYPPGGFHHQLGVAP------------ 570

  Fly   649 ATENEVTKHIDNHMNPNTTKVRRQQQQQHQQQQQQQQQQQQQQQQQNNNAVAQV------ANHLM 707
                       .|..|:.:..   .|.|.||...|.||..||||:.:...:|:|      |..|.
  Fly   571 -----------PHDYPSGSAF---LQLQPQQPHPQSQQHHQQQQRLSETFIAKVFXQRYYAESLN 621

  Fly   708 NDAKSLAAQQFLNNNNPSAVDNKAN------ILPVRSIASNAAAAA 747
            :...|.:..........:|:.:.|.      |..::.:|:.|||::
  Fly   622 SSTGSTSTTSSTVTTTTTAISSMATSRSDLLIDXLQFVAAAAAASS 667

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
jim	NP_001262221.1	C2H2 Zn finger	331..351	CDD:275368	8/19 (42%)
		COG5048	355..666	CDD:227381	78/353 (22%)
		C2H2 Zn finger	359..379	CDD:275368	10/19 (53%)
		C2H2 Zn finger	387..407	CDD:275368	7/19 (37%)
		C2H2 Zn finger	415..435	CDD:275368	8/19 (42%)
		C2H2 Zn finger	527..547	CDD:275368	8/19 (42%)
		C2H2 Zn finger	555..575	CDD:275368	7/20 (35%)
		C2H2 Zn finger	583..603	CDD:275368	2/19 (11%)
		C2H2 Zn finger	611..631	CDD:275368	2/22 (9%)
		C2H2 Zn finger	639..661	CDD:275368	0/21 (0%)
erm	NP_001259891.2	COG5048	<295..461	CDD:227381	76/270 (28%)
		C2H2 Zn finger	320..340	CDD:275368	8/19 (42%)
		C2H2 Zn finger	348..368	CDD:275368	10/19 (53%)
		zf-H2C2_2	363..385	CDD:463886	9/21 (43%)
		C2H2 Zn finger	376..396	CDD:275368	7/19 (37%)
		C2H2 Zn finger	404..424	CDD:275368	8/19 (42%)
		C2H2 Zn finger	432..452	CDD:275368	8/19 (42%)
		C2H2 Zn finger	460..478	CDD:275368	6/17 (35%)