Protein Alignment jim and Zfp607b

DIOPT Version :10

• Sequence 1: NP_001262221.1
• Gene: jim / 43924
• FlyBaseID: FBgn0027339
• Length: 938
• Species: Drosophila melanogaster
• Sequence 2: NP_940809.2
• Gene: Zfp607b / 112415
• MGIID: 2148237
• Length: 648
• Species: Mus musculus
• Alignment Length: 780
• Identity: 187/780 - (23%)
• Similarity: 274/780 - (35%)
• Gaps: 284/780 - (36%)

  Fly     1 MAINFSASFAACIAAGLKV-PRQIMY------------CIT--------QDTGQPYVLYKD---- 40
            :|::||....||:.|..|| .|.||.            ||:        :...:|::..|:
Mouse    19 VAVDFSQEEWACLDATQKVLYRNIMLETYSNLVAVVGRCISKPDLIVLLEQEKEPWMAVKEETDR 83

  Fly    41 -SQDAERNPGAIGATPAQWGSEMYPNIQQQAQQHLTAQQQQQQQQQNAAQAAAQAAAVAAAAGQP 104
             |.|.|....|...:|....|::  |:.:|:.:..:..
Mouse    84 PSPDVETCVEAENISPENHMSDV--NLHKQSIRQFSKT--------------------------- 119

  Fly   105 QSPPGGGQEARDNGSGDGRQQQVSPSSSPYPSVQQQQRANGAGDED----------PMNHQ-LAN 158
                   .:.:::...||      ||.|.:..:|..|     ||.|          |...| ||:
Mouse   120 -------FDLKESTFSDG------PSCSTFKGLQGYQ-----GDADERVTKKERVPPCTCQTLAH 166

  Fly   159 QQNPAPNQNQ-------SSNDPQHSGSNAGESGNPHVQQNGGPQNDPGNSFRTPDYYDPRHAAPQ 216
            ....|....:       ||...||...:|||.                       .|:.:..
Mouse   167 NTEKAYECKECGTCFDCSSALTQHQSVHAGEK-----------------------LYECKEC--- 205

  Fly   217 GGMLAPPGFPPLHYLNKGVLPMEQSGGGGGAGGGEAYALPEMLPAQQNGQQNAGPANTNANEGGA 281
                                             |:|:.||:.|...|.......|...|
Mouse   206 ---------------------------------GKAFRLPQELTRHQKSHSGEKPFQCN------ 231

  Fly   282 GANGSGGVGGATGASVGVGSVGVTSGGRTGNGPG--RPHK-----NKP----------------- 322
                                    ..|:..:.|.  :.||     .||
Mouse   232 ------------------------ECGKAFHLPDLLKYHKVIHTGEKPFECEVCGKFFSRVSSLA 272

  Fly   323 -----HSDLRLFKCLTCGKDFKQKSTLLQHDRIHTDARPFPCSECGKRF-------RQQS----- 370
                 |:|::.::|..|||.||::|.|:||.:||:..|||.|.:|||.|       :.||
Mouse   273 EHRIVHADVKPYECSECGKAFKRRSDLMQHQKIHSGERPFQCKDCGKAFIVLAQLAQHQSIHTGE 337

  Fly   371 ---------------HLTQHLRIHANEKPFTCPYCSRSFRQRAILNQHIRIHSGEKPFACPECGK 420
                           :|.:|..||..||||.|..|.::||.:..||:|.:.|:.||||.|..||.
Mouse   338 KLECKHCGKIFSSGFYLVRHQSIHTGEKPFGCHVCGKAFRLQVYLNEHQKTHTDEKPFKCKLCGS 402

  Fly   421 HFRQKAILNQHVRTHQDVSPHLIFKNG----------PHPTLWPSDVPFPGEDNDTKGDIAGTGG 475
            .||:|..|::|.:.|.:|.|:...:.|          .|.::.....||..:|         .|.
Mouse   403 AFRRKYQLSEHQKIHTNVKPYQCKECGKSFRRRSNFTEHQSIHTGKKPFECKD---------CGK 458

  Fly   476 GY--------HDEDSQG-TP----DGSGGMHYPSYFKDGKGQKILPEVLQHIGVRPANMPLYVRC 527
            .:        |.....| ||    :...|.|:.|.....|        ..|.|..|      ..|
Mouse   459 VFRLNIHLIRHQRFHSGKTPFECNECGKGFHFSSQLNYHK--------TIHTGQTP------FEC 509

  Fly   528 PICDKEFKQKTTLLQHGCIHIESRPYPCPECGKRFRQQSHLTQHLRIHTNEKPFGCMYCPRFFRQ 592
            ..|.|.||:..:||:||.||...:|:.|.||||.|.::|:|.||.:||::|:||.|..|.:.|..
Mouse   510 KECGKSFKRICSLLEHGVIHAAVKPFECSECGKTFNRRSNLIQHQKIHSDERPFECKDCGKAFTV 574

  Fly   593 RTILNQHLRIHTGEKPYKCGQCGKDFRQKAILDQHTRTHQGDRPFCCPMPNCRRRFATENEVTKH 657
            ...|.:|..||||:|.|:|.|||..||....|.||.|.|...:||.|  ..|.:.|.....:..|
Mouse   575 LAQLTRHHTIHTGKKSYECEQCGSAFRLPYQLTQHQRIHDDVKPFQC--KECGKGFVRGTALRIH 637

  Fly   658  657
            Mouse   638  637

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
jim	NP_001262221.1	C2H2 Zn finger	331..351	CDD:275368	10/19 (53%)
		COG5048	355..666	CDD:227381	113/353 (32%)
		C2H2 Zn finger	359..379	CDD:275368	9/46 (20%)
		C2H2 Zn finger	387..407	CDD:275368	7/19 (37%)
		C2H2 Zn finger	415..435	CDD:275368	8/19 (42%)
		C2H2 Zn finger	527..547	CDD:275368	9/19 (47%)
		C2H2 Zn finger	555..575	CDD:275368	10/19 (53%)
		C2H2 Zn finger	583..603	CDD:275368	5/19 (26%)
		C2H2 Zn finger	611..631	CDD:275368	10/19 (53%)
		C2H2 Zn finger	639..661	CDD:275368	4/19 (21%)
Zfp607b	NP_940809.2	KRAB	14..75	CDD:214630	14/55 (25%)
		C2H2 Zn finger	174..194	CDD:275368	4/19 (21%)
		C2H2 Zn finger	202..222	CDD:275368	6/55 (11%)
		COG5048	226..637	CDD:227381	134/465 (29%)
		C2H2 Zn finger	230..250	CDD:275368	5/49 (10%)
		C2H2 Zn finger	258..278	CDD:275368	0/19 (0%)
		C2H2 Zn finger	286..306	CDD:275368	10/19 (53%)
		C2H2 Zn finger	314..334	CDD:275368	7/19 (37%)
		C2H2 Zn finger	341..361	CDD:275368	2/19 (11%)
		C2H2 Zn finger	369..389	CDD:275368	7/19 (37%)
		C2H2 Zn finger	397..417	CDD:275368	8/19 (42%)
		C2H2 Zn finger	425..445	CDD:275368	2/19 (11%)
		C2H2 Zn finger	453..473	CDD:275368	3/28 (11%)
		C2H2 Zn finger	481..501	CDD:275368	4/27 (15%)
		C2H2 Zn finger	509..529	CDD:275368	9/19 (47%)
		C2H2 Zn finger	537..557	CDD:275368	10/19 (53%)
		C2H2 Zn finger	565..585	CDD:275368	5/19 (26%)
		C2H2 Zn finger	593..613	CDD:275368	10/19 (53%)
		C2H2 Zn finger	621..641	CDD:275368	4/19 (21%)