Protein Alignment jim and Mzf1

DIOPT Version :10

• Sequence 1: NP_001262221.1
• Gene: jim / 43924
• FlyBaseID: FBgn0027339
• Length: 938
• Species: Drosophila melanogaster
• Sequence 2: XP_006539528.1
• Gene: Mzf1 / 109889
• MGIID: 107457
• Length: 814
• Species: Mus musculus
• Alignment Length: 800
• Identity: 223/800 - (27%)
• Similarity: 313/800 - (39%)
• Gaps: 202/800 - (25%)

  Fly    26 CITQDTGQPYVLYKDS-QDAER-----NPG---------------AIGATPA---------QWGS 60
            |...:.....|..:|| .|.||     :||               |||...|         ||
Mouse    90 CAPPENEPALVKLEDSDSDDEREDILWDPGLEAARLRFRCFRYEDAIGPQEALAQLRELCHQW-- 152

  Fly    61 EMYPNI--QQQAQQHLTAQQ---------QQQQQQQNAAQAAAQAAAVAAAAGQPQSP------P 108
             :.|.:  ::|..:.|..:|         |.|.|.|........||.|.....:...|      .
Mouse   153 -LRPEVHSKEQVLELLVLEQFLGALPPEIQAQVQGQWPGSPEEAAALVDRLRWELDGPRKWVTVQ 216

  Fly   109 GGGQEARDNGSGDGRQQQVSPSS-SPYPSVQQQ------QRANGAGDEDPMNHQLANQQNPAPNQ 166
            ..|:|.        ..:::.||| .|.|.::.|      :...||..|.|:|..:..:.....|.
Mouse   217 VQGKEV--------LSEKMEPSSFQPRPHIKLQTPDPGAETPQGAMQELPLNLPMKEETELLGNP 273

  Fly   167 NQSSNDPQHSGSNAGESGNPHVQQNGG---PQNDPGNSFRTPDYYDPRHAAPQ-------GGMLA 221
            ....:.|..:...|..:..|...|..|   .|..| :|...|| ..|....|.       ||:.:
Mouse   274 ELLESGPLPAAQEAAATLLPKETQGHGTTLDQTSP-HSDTEPD-VPPWSEDPMPLWHEEVGGIFS 336

  Fly   222 PPGF---------------PPLHYLNKGVLPMEQSGG---GGGAGGGEAYALPEMLPAQQNGQQN 268
             |||               |.||.  ...|.|....|   .....||.|:||  :||:...|:|:
Mouse   337 -PGFTLQMDSITAEPDMMSPHLHV--PWDLDMASLSGQIQSPTTEGGFAHAL--VLPSDPGGEQD 396

  Fly   269 AGPANTNANEGGAGANGSGGVGGATGASVGVGSVGVTSGGRTGNGPGRPHKNKPHSDLRLFKCLT 333
              ||                   .......||...|.:......|..:.|.......:|..:|..
Mouse   397 --PA-------------------CEDPCPSVGPALVATRWHAPRGRSQSHPRSGTGAMRGGRCDV 440

  Fly   334 CGKDFKQKSTLLQHDRIHTDARPFPCSECGKRFRQQSHLTQHLRIHANEKPFTCPYCSRSFRQRA 398
            |||.|.|:|.||:|.:|||..|||.|.|||:.|.:.|||.:|...|..|:||.|..|.:.|.:.|
Mouse   441 CGKVFSQRSNLLRHQKIHTGERPFVCGECGRSFSRSSHLLRHQLTHTEERPFVCRDCGQGFVRSA 505

  Fly   399 ILNQHIRIHSGEKPFACPECGKHFRQKAILNQHVRTHQDVSPHLIFKNGPHPTLWP-SDVPFPGE 462
            .|.:|.|:|:||:||.|.|||:.|||::.|.||.|.|.|       ..||.|::.| :.||.|
Mouse   506 RLEEHRRVHTGEQPFRCTECGQSFRQRSNLLQHQRIHGD-------PPGPAPSILPLAGVPEP-- 561

  Fly   463 DNDTKGDIAGTGGGYHDEDSQGTPDGSGGMHYPSYFKDGKGQKILPE---VLQHIGVRPANMPLY 524
                                            |..|...:..:..|.   :|:|..|...:...
Mouse   562 --------------------------------PGPFPCSECCESFPRRAVLLEHQAVHTGDKSF- 593

  Fly   525 VRCPICDKEFKQKTTLLQHGCIHIESRPYPCPECGKRFRQQSHLTQHLRIHTNEKPFGCMYCPRF 589
             .|..|.:.|.:::.||||..:|...||:.|.|||:.|||:|:||||.||||.|:||.|..|.:.
Mouse   594 -GCVECGERFGRRSVLLQHRRVHSGERPFACAECGQSFRQRSNLTQHQRIHTGERPFACAECGKT 657

  Fly   590 FRQRTILNQHLRIHTGEKPYKCGQCGKDFRQKAILDQHTRTHQGDRPFCC--------------- 639
            ||||..|.||||:||||||:.|.:||:.|.|:..|.:|.|||.|::|:||
Mouse   658 FRQRPTLTQHLRVHTGEKPFACPECGQRFSQRLKLTRHQRTHTGEKPYCCGECGLGFTQVSRLTE 722

  Fly   640 -----------PMPNCRRRFATENEVTKHIDNHMN------PNTTKVRRQQQ--QQHQQQQQQQQ 685
                       ..|.|.:.|.....:|:|...|..      |...|..||:.  .||.:..:.::
Mouse   723 HQRIHTGERPFACPECGQSFRQHANLTQHRRIHTGERPYACPECGKAFRQRPTLTQHLRTHRHEK 787

  Fly   686 QQQQQQQQQNNNAVAQVANH 705
            ....|...:..|...::..|
Mouse   788 PFACQDCGRRFNQSTKLIQH 807

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
jim	NP_001262221.1	C2H2 Zn finger	331..351	CDD:275368	10/19 (53%)
		COG5048	355..666	CDD:227381	121/346 (35%)
		C2H2 Zn finger	359..379	CDD:275368	9/19 (47%)
		C2H2 Zn finger	387..407	CDD:275368	7/19 (37%)
		C2H2 Zn finger	415..435	CDD:275368	11/19 (58%)
		C2H2 Zn finger	527..547	CDD:275368	7/19 (37%)
		C2H2 Zn finger	555..575	CDD:275368	13/19 (68%)
		C2H2 Zn finger	583..603	CDD:275368	11/19 (58%)
		C2H2 Zn finger	611..631	CDD:275368	8/19 (42%)
		C2H2 Zn finger	639..661	CDD:275368	6/47 (13%)
Mzf1	XP_006539528.1	SCAN	121..232	CDD:128708	22/121 (18%)
		COG5048	416..807	CDD:227381	144/433 (33%)
		C2H2 Zn finger	438..458	CDD:275368	10/19 (53%)
		C2H2 Zn finger	466..486	CDD:275368	9/19 (47%)
		C2H2 Zn finger	494..514	CDD:275368	7/19 (37%)
		C2H2 Zn finger	522..542	CDD:275370	11/19 (58%)
		C2H2 Zn finger	567..587	CDD:275368	3/19 (16%)
		C2H2 Zn finger	595..615	CDD:275368	7/19 (37%)
		C2H2 Zn finger	623..643	CDD:275368	13/19 (68%)
		C2H2 Zn finger	651..671	CDD:275368	11/19 (58%)
		C2H2 Zn finger	679..699	CDD:275368	8/19 (42%)
		C2H2 Zn finger	707..727	CDD:275368	1/19 (5%)
		C2H2 Zn finger	735..755	CDD:275368	5/19 (26%)
		C2H2 Zn finger	763..783	CDD:275368	6/19 (32%)
		C2H2 Zn finger	791..811	CDD:275368	2/16 (13%)