| Sequence 1: | NP_001246631.1 | Gene: | axo / 43923 | FlyBaseID: | FBgn0262870 | Length: | 2179 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001633.1 | Gene: | APLP2 / 334 | HGNCID: | 598 | Length: | 763 | Species: | Homo sapiens |
| Alignment Length: | 452 | Identity: | 90/452 - (19%) |
|---|---|---|---|
| Similarity: | 144/452 - (31%) | Gaps: | 148/452 - (32%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 90 GTGGGGSNSGISGNNSAMIQGQKSNQYEKCAGPGDPGPCKQYIYKWRYEPTTNECTNFIWGGCEG 154
Fly 155 NPQNRFGTEAECLFHCIGGPHTLPPFLQSTTREPSTTESSMLLGLPYTQSPAQSPDGMGGAEGGD 219
Fly 220 GTTPVPIEQRG------PELTFAETGQGKTFIFAKNNTFIQMDGDII------------QTFQLR 266
Fly 267 LCR-EISFQFRTRL---------------PHGLLV----YHNVKNPDRIN----------LDPYA 301
Fly 302 -----------LYVIVEKGQ------LKVVHV---------------------FGKHSTSVTVGE 328
Fly 329 SLNRDEWHSVMVRIDVHGARLIARVDNSQEEVYLKGLNHEYNYGVSTNLPSVVLVGG-------- 385
Fly 386 ------------------LSSEEKLHGVKYITESFVGCIRNVVLSSGKAASDLLPIAPLVAT 429 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| axo | NP_001246631.1 | KU | 119..171 | CDD:238057 | 17/51 (33%) |
| Laminin_G_2 | 275..411 | CDD:280389 | 36/228 (16%) | ||
| EGF_CA | 433..476 | CDD:238011 | |||
| Laminin_G_2 | 514..640 | CDD:280389 | |||
| Laminin_G_2 | 698..817 | CDD:280389 | |||
| EGF_CA | 842..878 | CDD:238011 | |||
| Laminin_G_2 | 1112..1240 | CDD:280389 | |||
| EGF_CA | 1256..1297 | CDD:238011 | |||
| Laminin_G_2 | 1351..1503 | CDD:280389 | |||
| LamG | 1612..1733 | CDD:304605 | |||
| APLP2 | NP_001633.1 | A4_EXTRA | 42..204 | CDD:128326 | |
| GFLD subdomain. /evidence=ECO:0000255|PROSITE-ProRule:PRU01217 | 46..139 | ||||
| APP_N | 49..147 | CDD:280358 | |||
| CuBD subdomain. /evidence=ECO:0000255|PROSITE-ProRule:PRU01217 | 147..205 | ||||
| APP_Cu_bd | 149..204 | CDD:289676 | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 211..299 | 2/6 (33%) | |||
| Kunitz_BPTI | 309..361 | CDD:278443 | 18/66 (27%) | ||
| APP_E2 | 365..547 | CDD:289677 | 38/196 (19%) | ||
| APP_amyloid | 709..759 | CDD:287486 | |||
| Interaction with DAB2. /evidence=ECO:0000250 | 749..763 | ||||
| NPXY motif | 750..755 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_KOG4295 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.810 | |||||