DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment axo and Ambp

DIOPT Version :9

Sequence 1:	NP_001246631.1	Gene:	axo / 43923	FlyBaseID:	FBgn0262870	Length:	2179	Species:	Drosophila melanogaster
Sequence 2:	XP_008761981.1	Gene:	Ambp / 25377	RGDID:	2102	Length:	361	Species:	Rattus norvegicus

Alignment Length:	87	Identity:	28/87 - (32%)
Similarity:	40/87 - (45%)	Gaps:	13/87 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    86 GGSSGTGGGGSNSGISGNNSAMIQG--QKSNQYEKCAGPGDPGPCKQYIYKWRYEPTTNECTNFI 148
            ||..|          :|||.|..:.  |.......|..|...|||:.:...|.::....:|..||
  Rat   261 GGCLG----------NGNNFASEKECLQTCRTIAACNLPIVQGPCRAFAELWAFDAAQGKCIQFI 315

  Fly   149 WGGCEGNPQNRFGTEAECLFHC 170
            :|||:|| .|:|.:|.||..:|
  Rat   316 YGGCKGN-GNKFYSEKECKEYC 336

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
axo	NP_001246631.1	KU	119..171	CDD:238057	20/52 (38%)
		Laminin_G_2	275..411	CDD:280389
		EGF_CA	433..476	CDD:238011
		Laminin_G_2	514..640	CDD:280389
		Laminin_G_2	698..817	CDD:280389
		EGF_CA	842..878	CDD:238011
		Laminin_G_2	1112..1240	CDD:280389
		EGF_CA	1256..1297	CDD:238011
		Laminin_G_2	1351..1503	CDD:280389
		LamG	1612..1733	CDD:304605
Ambp	XP_008761981.1	Lipocalin	41..185	CDD:278490
		Kunitz_BPTI	230..281	CDD:278443	8/29 (28%)
		Kunitz_BPTI	285..337	CDD:278443	20/53 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4295
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810