DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment axo and T21D12.12

DIOPT Version :9

Sequence 1:	NP_001246631.1	Gene:	axo / 43923	FlyBaseID:	FBgn0262870	Length:	2179	Species:	Drosophila melanogaster
Sequence 2:	NP_499892.1	Gene:	T21D12.12 / 188695	WormBaseID:	WBGene00020651	Length:	183	Species:	Caenorhabditis elegans

Alignment Length:	99	Identity:	30/99 - (30%)
Similarity:	41/99 - (41%)	Gaps:	14/99 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    80 AGGSPAGGSSGTGGGGSN--SGISGNNSAMIQGQK---SNQYE--KCAGPGDPGPCKQYIYKWRY 137
            :|..|||.:||...|.||  .|....|......::   |.||:  |....|...|  :|.:...|
Worm    92 SGAYPAGATSGQTVGCSNCPHGYECQNQQCCPTKENTCSLQYDAGKFGSSGKHTP--RYFFSKSY 154

  Fly   138 EPTTNECTNFIWGGCEGNPQNRFGTEAECLFHCI 171
            :    .|..|.:.|.:|| .|.|.|..||...|:
Worm   155 K----NCMLFTFYGRDGN-ANNFATYNECKNFCM 183

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
axo	NP_001246631.1	KU	119..171	CDD:238057	14/51 (27%)
		Laminin_G_2	275..411	CDD:280389
		EGF_CA	433..476	CDD:238011
		Laminin_G_2	514..640	CDD:280389
		Laminin_G_2	698..817	CDD:280389
		EGF_CA	842..878	CDD:238011
		Laminin_G_2	1112..1240	CDD:280389
		EGF_CA	1256..1297	CDD:238011
		Laminin_G_2	1351..1503	CDD:280389
		LamG	1612..1733	CDD:304605
T21D12.12	NP_499892.1	Kunitz_BPTI	23..77	CDD:278443
T21D12.12	NP_499892.1	KU	127..183	CDD:238057	18/62 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4295
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810