DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Rok and KIN82

DIOPT Version :9

Sequence 1:NP_536796.2 Gene:Rok / 43916 FlyBaseID:FBgn0026181 Length:1390 Species:Drosophila melanogaster
Sequence 2:NP_010015.3 Gene:KIN82 / 850453 SGDID:S000000687 Length:720 Species:Saccharomyces cerevisiae


Alignment Length:515 Identity:147/515 - (28%)
Similarity:244/515 - (47%) Gaps:124/515 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly     6 ETVTKQRSMDV-ERRRRA-----NT----LERE----MRDPTSICNVDCLLDTVSALVSDCDHES 56
            ||...|..|:: .|.|||     ||    |.||    ::.|.|:.::             .:...
Yeast   250 ETRKDQIPMNITPRLRRAASEPFNTAKDGLMREDYIALKQPPSLGDI-------------VEPRR 301

  Fly    57 LRRLKNIEQYAAKYKPLAMQINQLRMNVEDFHFIKLIGAGAFGEVQLVRHKSSSQVYAMKRLSKF 121
            .|||:. :.:..|::.:.::       .:.|..|:|:|.|..|:|.|||.:.::|::|:|.|:|.
Yeast   302 SRRLRT-KSFGNKFQDITVE-------PQSFEKIRLLGQGDVGKVYLVRERDTNQIFALKVLNKH 358

  Fly   122 EMMKRPDSAFFWEERHIMAHANSEWIVQLHFAFQDAKYLYMVMDFMPGGDIVSLMGDYD---IPE 183
            ||:||........|:.|:|.::..:||.|:.:||...|||:.|::..||:....:....   |.|
Yeast   359 EMIKRKKIKRVLTEQEILATSDHPFIVTLYHSFQTKDYLYLCMEYCMGGEFFRALQTRKSKCIAE 423

  Fly   184 KWAIFYTMEVVLALDTIHNMGFVHRDVKPDNMLLDSYGHLKLADFGTCMRMGANGQVV------- 241
            :.|.||..|||.||:.:|.:||::||:||:|:||...||:.|:||...::...:.:..       
Yeast   424 EDAKFYASEVVAALEYLHLLGFIYRDLKPENILLHQSGHVMLSDFDLSIQATGSKKPTMKDSTYL 488

  Fly   242 ----------SSNAVGTPDYISPEVLQSQGVDNEYGRECDWWSVGIFLYEMLFGETPFYADSLVG 296
                      :::.|||.:|::|||::..|    :....|||::||.:||||||.|||..|:...
Yeast   489 DTKICSDGFRTNSFVGTEEYLAPEVIRGNG----HTAAVDWWTLGILIYEMLFGCTPFKGDNSNE 549

  Fly   297 TYGKIMDHKNSLSFPPEVEISEQAKALIRAFLT-DRTQRLG-RYGIEDIKAHPFFRNDTWSFDNI 359
            |:..|:  ...:.||.:.|:|:..|.||:..|. :..:||| :.|..|||.||||:...|||  :
Yeast   550 TFSNIL--TKDVKFPHDKEVSKNCKDLIKKLLNKNEAKRLGSKSGAADIKRHPFFKKVQWSF--L 610

  Fly   360 RESVPPVVPELS---------------------SDDDTRNF-EDIERDEKPEEVFPVPKGFDGNH 402
            |...||::|.|:                     |:.:|:.| |.:..|::.:|..          
Yeast   611 RNQDPPLIPALNDNGCELPFILSCNKHPKRNSVSEQETKMFCEKVANDDEIDEAD---------- 665

  Fly   403 LPFIGFTYTGDYQLLSSDTVDAESKEANVANSGAASNNHGHG------------HNHRHR 450
             ||..|           :::....|:.|:.   ..|.|:.:|            ||..||
Yeast   666 -PFHDF-----------NSMSLTKKDHNIL---TYSENYTYGKILYKATCTRPRHNSSHR 710

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
RokNP_536796.2 STKc_ROCK 61..411 CDD:270747 120/393 (31%)
S_TKc 87..349 CDD:214567 100/283 (35%)
SbcC 484..1088 CDD:223496
Rho_Binding 963..1027 CDD:286056
PH_ROCK 1134..1250 CDD:269948
C1 1254..1307 CDD:197519
KIN82NP_010015.3 STKc_phototropin_like 322..623 CDD:270726 110/308 (36%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

Return to query results.
Submit another query.