DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Rok and AT4G14350

DIOPT Version :9

Sequence 1:	NP_536796.2	Gene:	Rok / 43916	FlyBaseID:	FBgn0026181	Length:	1390	Species:	Drosophila melanogaster
Sequence 2:	NP_001329677.1	Gene:	AT4G14350 / 827078	AraportID:	AT4G14350	Length:	551	Species:	Arabidopsis thaliana

Alignment Length:	498	Identity:	171/498 - (34%)
Similarity:	266/498 - (53%)	Gaps:	97/498 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 ERRRRANTLEREMRDPTSICNVDCLLDTVSALVSDCDHESLRRLKNIEQYAAKYKPLAMQINQLR 81
            ||:.|...||:::               .:|.||:.:..:|  ||::|....:|    |:..:.:
plant    70 ERKERRKMLEKKL---------------AAAEVSEEEQNNL--LKDLEMKETEY----MRRQRHK 113

  Fly    82 MNVEDFHFIKLIGAGAFGEVQLVRHKSSSQVYAMKRLSKFEMMKRPDSAFFWEERHIMAHANSEW 146
            |..:||..:.:||.||||||::.|.|.:..|||||:|.|.||::|........||:::|..:|..
plant   114 MGADDFEPLTMIGKGAFGEVRICREKGTGNVYAMKKLKKSEMLRRGQVEHVKAERNLLAEVDSNC 178

  Fly   147 IVQLHFAFQDAKYLYMVMDFMPGGDIVSLMGDYD-IPEKWAIFYTMEVVLALDTIHNMGFVHRDV 210
            ||:|:.:|||.:|||::|:::||||:::|:...| :.|..|.||..|.|||:::||...::|||:
plant   179 IVKLYCSFQDEEYLYLIMEYLPGGDMMTLLMRKDTLTEDEARFYIGETVLAIESIHKHNYIHRDI 243

  Fly   211 KPDNMLLDSYGHLKLADFGTCMRM-----------------GA---------------------- 236
            ||||:|||..||:||:|||.|..:                 ||
plant   244 KPDNLLLDKDGHMKLSDFGLCKPLDCSNLQEKDFTVARNVSGALQSDGRPVATRRTQQEQLLNWQ 308

  Fly   237 -NGQVVSSNAVGTPDYISPEVLQSQGVDNEYGRECDWWSVGIFLYEMLFGETPFYADSLVGTYGK 300
             |.::::.:.|||||||:||||..:|    ||.||||||:|..:||||.|..|||:|..:.|..|
plant   309 RNRRMLAYSTVGTPDYIAPEVLLKKG----YGMECDWWSLGAIMYEMLVGFPPFYSDDPMTTCRK 369

  Fly   301 IMDHKNSLSFPPEVEISEQAKALIRAFLTDRTQRLGRYGIEDIKAHPFFRNDTWSFDNIRESVPP 365
            |::.:|.|.||.||.:|.:||.||...|.:..||||..|.::||.||:||...|.  .:.:....
plant   370 IVNWRNYLKFPDEVRLSPEAKDLICRLLCNVEQRLGTKGADEIKGHPWFRGTEWG--KLYQMKAA 432

  Fly   366 VVPELSSDDDTRNFEDIERDEK--PEEVFPVP--KGFDGNHLPFIGFTYTGDYQLLSSDTVD--A 424
            .:|:::.:.||:|||..|..:|  |:.....|  |......:.|:|:||. :.::::.|.:.  |
plant   433 FIPQVNDELDTQNFEKFEETDKQVPKSAKSGPWRKMLSSKDINFVGYTYK-NVEIVNDDQIPGIA 496

  Fly   425 ESKEANVANSGAASNNHGHGHNHRHRPSNSNELKRLEALLERE 467
            |.|:.:               |...|||       :::|.|.|
plant   497 ELKKKS---------------NKPKRPS-------IKSLFEDE 517

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rok	NP_536796.2	STKc_ROCK	61..411	CDD:270747	149/394 (38%)
		S_TKc	87..349	CDD:214567	126/302 (42%)
		SbcC	484..1088	CDD:223496
		Rho_Binding	963..1027	CDD:286056
		PH_ROCK	1134..1250	CDD:269948
		C1	1254..1307	CDD:197519
AT4G14350	NP_001329677.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D759391at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920