DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Rok and AT3G23310

DIOPT Version :9

Sequence 1:NP_536796.2 Gene:Rok / 43916 FlyBaseID:FBgn0026181 Length:1390 Species:Drosophila melanogaster
Sequence 2:NP_188973.2 Gene:AT3G23310 / 821911 AraportID:AT3G23310 Length:568 Species:Arabidopsis thaliana


Alignment Length:539 Identity:178/539 - (33%)
Similarity:279/539 - (51%) Gaps:111/539 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly    10 KQRSMDVERRRRANTLEREMRDPTSICNVDCLLDTVSALVSDCDHESLRRLKNIEQYAAKYKPLA 74
            ||.....:|:.|.:.||.::               .:|.||:.:.::|  ||::|:...:|    
plant    64 KQVQSQQQRKERRDMLENKL---------------AAAEVSEEEQKNL--LKDLEKKETEY---- 107

  Fly    75 MQINQLRMNVEDFHFIKLIGAGAFGEVQLVRHKSSSQVYAMKRLSKFEMMKRPDSAFFWEERHIM 139
            |:..:.:|..:||..:.:||.||||||::.|.|::..|||||:|.|.||::|........||:::
plant   108 MRRQRHKMGTDDFEPLTMIGKGAFGEVRICREKTTGNVYAMKKLKKSEMLRRGQVEHVKAERNLL 172

  Fly   140 AHANSEWIVQLHFAFQDAKYLYMVMDFMPGGDIVSLMGDYD-IPEKWAIFYTMEVVLALDTIHNM 203
            |..:|..||:|:.:|||.:|||::|:::||||:::|:...| :.|..|.||..|.|||:::||..
plant   173 AEVDSNCIVKLYCSFQDEEYLYLIMEYLPGGDMMTLLMRKDTLTEDEARFYVGETVLAIESIHKH 237

  Fly   204 GFVHRDVKPDNMLLDSYGHLKLADFGTCMRM-----------------GA--------------- 236
            .::|||:||||:|||..||:||:|||.|..:                 ||               
plant   238 NYIHRDIKPDNLLLDRSGHMKLSDFGLCKPLDCSILQEKDFVVAHNLSGALQSDGRPVAPRRTRS 302

  Fly   237 ----------NGQVVSSNAVGTPDYISPEVLQSQGVDNEYGRECDWWSVGIFLYEMLFGETPFYA 291
                      |.::::.:.|||||||:||||..:|    ||.||||||:|..:||||.|..|||:
plant   303 QMEQLQNWQRNRRMLAYSTVGTPDYIAPEVLLKKG----YGMECDWWSLGAIMYEMLVGFPPFYS 363

  Fly   292 DSLVGTYGKIMDHKNSLSFPPEVEISEQAKALIRAFLTDRTQRLGRYGIEDIKAHPFFRNDTWSF 356
            |..:.|..||::.||.|.||.||.:|.:||.||...|.:..||:|..|..:||.||:|....|  
plant   364 DEPMTTCRKIVNWKNYLKFPDEVRLSPEAKDLICRLLCNVEQRIGTKGANEIKEHPWFSGVEW-- 426

  Fly   357 DNIRESVPPVVPELSSDDDTRNFEDIERDEKPEEVFPVPKG------FDGNHLPFIGFTYTGDYQ 415
            :.:.:.....:|:::.:.||:|||..|..:|  :|...||.      .....:.|:|:||. :.:
plant   427 EKLYQMKAAFIPQVNDELDTQNFEKFEETDK--QVPKTPKSGPWRKMLSSKDINFVGYTYK-NVE 488

  Fly   416 LLSSDTVD--AESKEANVANSGAASNNHGHGHNHRHRPSNSNELKRLEALLERERGRSEALEQQD 478
            :::.|.:.  ||.|:.:....               |||       :::|.|.|...|....|  
plant   489 IVNHDQLPGIAELKKKSTKPK---------------RPS-------IKSLFEDESASSTTSHQ-- 529

  Fly   479 AG-----LRQQIELITKRE 492
             |     |..|||:..|.:
plant   530 -GSFMKLLPTQIEVPEKED 547

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
RokNP_536796.2 STKc_ROCK 61..411 CDD:270747 148/398 (37%)
S_TKc 87..349 CDD:214567 126/304 (41%)
SbcC 484..1088 CDD:223496 4/9 (44%)
Rho_Binding 963..1027 CDD:286056
PH_ROCK 1134..1250 CDD:269948
C1 1254..1307 CDD:197519
AT3G23310NP_188973.2 STKc_NDR_like 118..485 CDD:270750 143/374 (38%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D759391at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.920

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