Protein Alignment Rok and rock2

DIOPT Version :9

• Sequence 1: NP_536796.2
• Gene: Rok / 43916
• FlyBaseID: FBgn0026181
• Length: 1390
• Species: Drosophila melanogaster
• Sequence 2: XP_004914525.1
• Gene: rock2 / 100493965
• XenbaseID: XB-GENE-959451
• Length: 1399
• Species: Xenopus tropicalis
• Alignment Length: 1426
• Identity: 622/1426 - (43%)
• Similarity: 886/1426 - (62%)
• Gaps: 107/1426 - (7%)

  Fly     9 TKQRSMDVERRRRANTLEREMRDPTSICNVDCLLDTVSALVSDCDHESLRRLKNIEQYAAKYKPL 73
            |::..|:..|:    |||..:|||.|..||:.|||.::::|.|.|..:||:.|||:.:..:|:.:
 Frog     4 TQEECMNSRRQ----TLEAILRDPRSPINVEGLLDGLNSIVLDLDFPALRKNKNIDNFLNRYEKI 64

  Fly    74 AMQINQLRMNVEDFHFIKLIGAGAFGEVQLVRHKSSSQVYAMKRLSKFEMMKRPDSAFFWEERHI 138
            ..::.:|:|..||:..:|:||.||||||||||||.|.:|||||.||||||:||.|||||||||.|
 Frog    65 VREVRKLQMKAEDYDVVKVIGRGAFGEVQLVRHKGSQKVYAMKLLSKFEMIKRSDSAFFWEERDI 129

  Fly   139 MAHANSEWIVQLHFAFQDAKYLYMVMDFMPGGDIVSLMGDYDIPEKWAIFYTMEVVLALDTIHNM 203
            ||.|||.|:|||..||||.|:|||||::|||||:|:||.:||:|||||.|||.||||||:.||:|
 Frog   130 MAFANSPWVVQLFCAFQDEKHLYMVMEYMPGGDLVNLMSNYDVPEKWAKFYTAEVVLALNAIHSM 194

  Fly   204 GFVHRDVKPDNMLLDSYGHLKLADFGTCMRMGANGQVVSSNAVGTPDYISPEVLQSQGVDNEYGR 268
            |.:||||||||||||.|||||||||||||:|...|.|....|||||||||||||:|||.|..|||
 Frog   195 GLIHRDVKPDNMLLDKYGHLKLADFGTCMKMDQTGMVRCDTAVGTPDYISPEVLKSQGGDGYYGR 259

  Fly   269 ECDWWSVGIFLYEMLFGETPFYADSLVGTYGKIMDHKNSLSFPPEVEISEQAKALIRAFLTDRTQ 333
            ||||||||:||:|||.|:||||||||||||.|||||||||:||.:||||..||.||.||||||..
 Frog   260 ECDWWSVGVFLFEMLVGDTPFYADSLVGTYSKIMDHKNSLNFPEDVEISVHAKNLICAFLTDREV 324

  Fly   334 RLGRYGIEDIKAHPFFRNDTWSFDNIRESVPPVVPELSSDDDTRNFEDIERDEKPEEVFPVPKGF 398
            ||||.||||||.||||:||.|::|||||:|.||||||:||.||.||:|||.|:...|.||.||.|
 Frog   325 RLGRNGIEDIKQHPFFKNDQWNWDNIRETVAPVVPELASDIDTSNFDDIEDDKGDAETFPNPKAF 389

  Fly   399 DGNHLPFIGFTYTGDYQLLSSDTVDAESKEANVANSGAASNNHGHGHNHRHRPSNSNELKRLEAL 463
            .||.||||||||..:..|||..:.:.:.|     ||.|........|..:       .:.:||..
 Frog   390 AGNQLPFIGFTYYRENLLLSESSRNCKEK-----NSSAQPMKEQSAHLQK-------VINKLEEQ 442

  Fly   464 LERERGRSEALEQQDAGLRQQIELITKREAE-------LQRIASEYEKDLALRQHNYKVAMQKVE 521
            |..|....:.|||:...:..::|...|...|       ::....:.|::.||.||......:|.|
 Frog   443 LHNEMQTKDELEQKFRAVNLRLEKTVKELDEEANARKSIESTTRQLEREKALLQHKSTEYQRKAE 507

  Fly   522 QEIELRKKTEALLVETQRNLENEQKTRARDLNINDKVVSLEKQLLEMEQSYKTETENTQKLKKHN 586
            .:.:.::..|..:...:..||:.::........|:|:..|::||.|.....:||::...:|:|..
 Frog   508 NDADRKRSLENEVNSLKDQLEDLKRRNQNSQISNEKMNQLQRQLDEANAQLRTESDAAARLRKTQ 572

  Fly   587 AELDFTVKSQEEKVRDMVDMIDTLQKHKEELGQENAELQALVVQEKNLRSQLKEMHKEAENKMQT 651
            .|:...::..|...|::.|....|:..|.:|.::...||:.:..|:..|:|..|:..:.:.::..
 Frog   573 TEMSKQIQQLETNNRELQDKTCMLENAKLKLEKDFINLQSALESERRDRTQGSEVISDLQGRISV 637

  Fly   652 LINDIERTMCREQKAQEDNRALLEKISDLEKAHAGLD----FELKAAQGRYQQEVKAHQETEKSR 712
            |..|:::......:|:.:.:.:.|.::.|||..:.|:    ::|||.|...::|...|:.| |:|
 Frog   638 LEEDLKKGKELLARAEAEKQQMHEGLAILEKEKSNLEIDMTYKLKALQQSVEKEEAEHKAT-KAR 701

  Fly   713 LVSR-------EEANLQEVKALQSKLNEEKSARIKADQHSQEKERQLSMLSVDYRQIQLRLQKLE 770
            |..:       ||...:.:|.::.||:||:..:.:.:....|.|:|.|||..|.:|.:.::.:||
 Frog   702 LADKNKIYQSIEETKSEAMKDMEKKLHEERLVKQRLENSLLETEKQYSMLDCDLKQAKQKINELE 766

  Fly   771 GECRQESEKVAALQSQLDQEHSKRNALLSELSLHSSEVAHLRSRENQLQKELSTQREAKRRFEED 835
            ....:.||.|..|..:.:||..|||...::|.:...:|..|:..|.||::|::...|.|...|:.
 Frog   767 SLKDKLSEDVKNLTLKAEQEAQKRNLTHNDLKMQIQQVNSLKMSEKQLKQEINHLTEIKLNLEKQ 831

  Fly   836 LTQLKSTHHEALANNRELQAQLEAEQCFSRLYKTQANENREESAER-------LSKIEDLEEERV 893
            ..:|:....:|....:|||.||||||.||.|||||..|.:||..::       ..|:::|::||.
 Frog   832 NNELRKERVDADGQMKELQDQLEAEQYFSTLYKTQVRELKEECEDKSKMCKEVQQKVQELQDERD 896

  Fly   894 SLKHQVQVAVARADSEALARSIAEETVADLEKEKTIKELELKDFVMKHRNEINAKEAALATLKEA 958
            ||..|:::.:.:||||.||||||||..:||||||.:||||:|:.:.:|:.|:..|.|.:|:|:||
 Frog   897 SLAAQLEITLTKADSEQLARSIAEEQYSDLEKEKIMKELEIKEMMARHKQELAEKYATIASLEEA 961

  Fly   959 ENELHKKLGQKAAEYEDLVQQHKKQQEELALMRSSKDEEITKLLDKCK------NEVLLKQVAVN 1017
            ...|...:|..|.|.|||..:.|:.||   |:::.|:||.:.:..|.:      .|..||..|||
 Frog   962 NKTLTIDVGNLANEKEDLNNKLKETQE---LIQNLKEEESSIITVKAQFEKQLLTERTLKTQAVN 1023

  Fly  1018 KLAEVMNRRDSDLPKQKNKARSTAELRKKEKEMRRLQQELSQERDKFNQLLLKHQ----DLQQLC 1078
            ||||:|||:   ||   .|.....::|:||||.|:||.:|..||:||:||:.|:|    |:|.|.
 Frog  1024 KLAEIMNRK---LP---TKRGPDTDVRRKEKENRKLQLDLKSEREKFSQLVFKYQREVNDMQALI 1082

  Fly  1079 AEEQQLKQKMVMEIDCKATEIENLQSKLN------ETASLSS--ADNDPEDSQHSSLLSLTQDSV 1135
            |:|.|.:.::.|.:|.|.::||.|:|:|.      ::.|:.|  .|.|.:|....|.|
 Frog  1083 ADENQARVELQMALDSKDSDIEQLRSQLQSMNLGLDSTSIGSGHGDTDADDGFPESRL------- 1140

  Fly  1136 FEGWLSVPNKQNRRRGHGWKRQYVIVSSRKIIFYNSDIDKHNTTDAVLILDLSKVYHVRSVTQGD 1200
             |||||:|.:..::  .||.::||:||||||:||:|:.|| ..::..::||:.|::|||.|||.|
 Frog  1141 -EGWLSLPLRNAKK--FGWNKKYVVVSSRKILFYDSEQDK-ELSNPSMVLDIDKLFHVRPVTQTD 1201

  Fly  1201 VIRADAKEIPRIFQLLYAGEGASHRPDEQSQLDVSVLHGNCNEERPGTIVHKGHEFVHITYHMPT 1265
            |.||||||||||||:|||.||.| :.:::.|:|..        |:...|.||||||:...||.||
 Frog  1202 VYRADAKEIPRIFQILYANEGES-KKEQEFQVDPL--------EKSNYICHKGHEFIPTLYHFPT 1257

  Fly  1266 ACEVCPKPLWHMFKPPAAYECKRCRNKIHKEHVDKHDP-LAPCKLNHDPRSARDMLLLAATPEDQ 1329
            :|:.|.||||||||||||.||:||..|.||:|:||.:. :||||:|:|..:|:::||||.:.|:|
 Frog  1258 SCDACMKPLWHMFKPPAALECRRCHIKCHKDHMDKKEEIIAPCKVNYDISTAKNLLLLANSTEEQ 1322

  Fly  1330 SLWVARLLKRIQK----SGYKAASYNNNSTDGSKISPSQSTRSSYKPYAVNVQRSATLPAN 1386
            ..||:||:|:|.|    |.::|.|   :....:|.|.:||.|   :|       |..||.|
 Frog  1323 QKWVSRLVKKIPKKPPASDHQARS---SPRPPAKASLNQSMR---RP-------SRQLPPN 1370

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rok	NP_536796.2	STKc_ROCK	61..411	CDD:270747	247/349 (71%)
		S_TKc	87..349	CDD:214567	197/261 (75%)
		SbcC	484..1088	CDD:223496	203/638 (32%)
		Rho_Binding	963..1027	CDD:286056	27/69 (39%)
		PH_ROCK	1134..1250	CDD:269948	53/115 (46%)
		C1	1254..1307	CDD:197519	32/53 (60%)
rock2	XP_004914525.1	STKc_ROCK2	25..403	CDD:270771	259/377 (69%)
		S_TKc	78..340	CDD:214567	197/261 (75%)
		Smc	<432..1113	CDD:224117	218/697 (31%)
		HR1_ROCK2	492..558	CDD:212028	15/65 (23%)
		Rho_Binding	966..1032	CDD:286056	26/68 (38%)
		PH_ROCK	1138..1242	CDD:269948	55/123 (45%)
		C1	1246..1292	CDD:237996	29/45 (64%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	416	1.000	Domainoid score	I653
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H21010
Inparanoid	1	1.050	1059	1.000	Inparanoid score	I254
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D36370at33208
OrthoFinder	1	1.000	-	-		FOG0001986
OrthoInspector	1	1.000	-	-		otm49226
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1475
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.060