DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Gk1 and Kat60

DIOPT Version :9

Sequence 1:	NP_524655.1	Gene:	Gk1 / 43913	FlyBaseID:	FBgn0025592	Length:	538	Species:	Drosophila melanogaster
Sequence 2:	NP_001262276.1	Gene:	Kat60 / 53566	FlyBaseID:	FBgn0040208	Length:	605	Species:	Drosophila melanogaster

Alignment Length:	179	Identity:	41/179 - (22%)
Similarity:	62/179 - (34%)	Gaps:	60/179 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   121 WLDNRTTSTVEELLETIPNNARNINYLRPLCGLPLSPYFSGVKLRWLRDNVPVVSQAMEKGTAMF 185
            |.|.......:.|||    .|..:..|.|       .||.|::..|             ||..|.
  Fly   325 WSDIADLHDAKRLLE----EAVVLPMLMP-------DYFKGIRRPW-------------KGVLMV 365

  Fly   186 GTIDTWLMYNLTGGK---------DCGVHKTDVTNASRTMLMNIETLQWDANLLKF--FGLPKTI 239
            |...|        ||         :||....:|::|:.|.....|:.:....|.:.  |..|.||
  Fly   366 GPPGT--------GKTMLAKAVATECGTTFFNVSSATLTSKYRGESEKMVRLLFEMARFYAPSTI 422

  Fly   240 ----LPEICS--SSEFYGSIAQGV-------LQGIGITSVLGDQQAALV 275
                :..:||  .||.....::.|       :.|:|    .|::||.:|
  Fly   423 FIDEIDSLCSRRGSESEHEASRRVKSELLVQMDGVG----GGEEQAKVV 467

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gk1	NP_524655.1	glycerol_kin	18..522	CDD:273549	41/179 (23%)
Gk1	NP_524655.1	FGGY_GK1-3_metazoa	18..522	CDD:212664	41/179 (23%)
Kat60	NP_001262276.1	HCV_NS5a_C	<163..243	CDD:289693
		P-loop_NTPase	325..>381	CDD:304359	19/87 (22%)
		AAA	358..496	CDD:214640	30/135 (22%)
		AAA	362..495	CDD:278434	27/118 (23%)
		Vps4_C	<570..603	CDD:286426
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0554
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900