DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Gk1 and Atad2

DIOPT Version :9

Sequence 1:	NP_524655.1	Gene:	Gk1 / 43913	FlyBaseID:	FBgn0025592	Length:	538	Species:	Drosophila melanogaster
Sequence 2:	NP_001128351.1	Gene:	Atad2 / 314993	RGDID:	1304849	Length:	1373	Species:	Rattus norvegicus

Alignment Length:	357	Identity:	75/357 - (21%)
Similarity:	127/357 - (35%)	Gaps:	100/357 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   203 GVHKTDVTNASRTMLMNIETLQWDANL--------------LKFFGLPKTILPEICSSSE----- 248
            |::|..:...:.  |.:::.:|.|:::              ||...|...:.||:....:
  Rat   384 GIYKDRMKIGAN--LADVDPMQLDSSVRFDSVGGLSSHIAALKEMVLFPLLYPEVFEKFKIQPPR 446

  Fly   249 ---FYGSIAQG---VLQGIGITSVLGDQQAALV---GQQCLAK--GQAKATYGTGCFLLYNTGPS 302
               |||....|   |.:.:......||::.|..   |..||:|  |:::...
  Rat   447 GCLFYGPPGTGKTLVARALANECSRGDKRVAFFMRKGADCLSKWVGESERQL------------- 498

  Fly   303 IVHSTHGLLTTVGYQLGRKAVPFYALEGSVSIAGAAFNWLRDNMNLIQNSGQIETMASTVDNSLD 367
                  .||....||: |.|:.|             |:.: |.:..:::|.|.:..:|.|...|.
  Rat   499 ------RLLFDQAYQM-RPAIIF-------------FDEI-DGLAPVRSSRQDQIHSSIVSTLLA 542

  Fly   368 VYFVPAFNGLYAPYWNQDARGVICGLSEETTSEHIVRATLEAVCFQVRDILDSM-HKDCKIPLAK 431
            :     .:||       |:||.|..:......:.|..|......|. |:.|.|: .||.:..:.|
  Rat   543 L-----MDGL-------DSRGEIVVIGATNRLDSIDPALRRPGRFD-REFLFSLPDKDARKEILK 594

  Fly   432 LMV-DGGMTVNNLFL-QLQSDLVGIQVLRAKIAETTALGA------AMAAYKAVENRYQMEAPLS 488
            :.. |......::|| :|..:.||.            .||      |.||..|:..||......|
  Rat   595 IHTRDWNPKPVDMFLEELAENCVGY------------CGADIKSICAEAALCALRRRYPQIYTTS 647

  Fly   489 KSGPREAIKPSISATDRNLRYQKWKMAIDRSL 520
            :....:....:|||.|.....||...|..|::
  Rat   648 EKLQLDLSSINISAKDFETAMQKIIPASQRAV 679

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gk1	NP_524655.1	glycerol_kin	18..522	CDD:273549	75/357 (21%)
Gk1	NP_524655.1	FGGY_GK1-3_metazoa	18..522	CDD:212664	75/357 (21%)
Atad2	NP_001128351.1	AAA	444..585	CDD:214640	39/187 (21%)
		AAA	449..583	CDD:278434	38/180 (21%)
		Bromo_AAA	972..1082	CDD:99957
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0554
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900