DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Gk1 and CG10793

DIOPT Version :9

Sequence 1:	NP_524655.1	Gene:	Gk1 / 43913	FlyBaseID:	FBgn0025592	Length:	538	Species:	Drosophila melanogaster
Sequence 2:	NP_570054.2	Gene:	CG10793 / 31308	FlyBaseID:	FBgn0029656	Length:	479	Species:	Drosophila melanogaster

Alignment Length:	271	Identity:	58/271 - (21%)
Similarity:	100/271 - (36%)	Gaps:	58/271 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   149 PLCGLPLSPYFSGVKL-RW----------LRDNVPVVSQAMEKGTAMFGTIDTWLMYNLTGGKDC 202
            |...||..|..:...| .|          |.:..|:..:.||..|...|..:...:.::..|.|
  Fly   113 PAKELPKKPPTTDASLANWHIGVGAATQALSNEQPLQIKKMETATESNGQDNACEIEHVHLGGD- 176

  Fly   203 GVHKTDVTNASRTMLMNIETLQWD--ANLLKFFGLPKTI---LPEICSSSEFYGSIAQGVLQGIG 262
                 ||..:|         |:|.  |.|:|...|.:.|   ..::|.:......|.:.||..|.
  Fly   177 -----DVLFSS---------LEWQSLAELVKTSILQENIKIKWSDVCGNQRAIELIKEAVLTPIE 227

  Fly   263 ITSV----LGDQQAALV------GQQCLAKGQAKATYGTGCFLLYNTGPSIVHS-----THGLLT 312
            ...:    |...::.|:      |:..|||.....|.|...|  :|...||:.|     :..:|.
  Fly   228 FPQLFAHGLKPWRSLLLHGPPGSGKTLLAKALYSETQGQVTF--FNITASIMVSKWRGESEKILR 290

  Fly   313 TVGYQLGRKA---VPFYALEGSVSIAGAAFNWLRDNMNLIQNSGQIETMASTVDNSLDVYFVPAF 374
            .:.:...::|   :.|..:|...|....|    .|:.:..:...::..:...:::||:..||.|.
  Fly   291 VLFHMAAKRAPSVIFFDEIESLTSKRDRA----TDHESSKRFKNELLQLLDGMEHSLNGVFVLAS 351

  Fly   375 NGLYAPYWNQD 385
            ..|  | |:.|
  Fly   352 TNL--P-WDID 359

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gk1	NP_524655.1	glycerol_kin	18..522	CDD:273549	58/271 (21%)
Gk1	NP_524655.1	FGGY_GK1-3_metazoa	18..522	CDD:212664	58/271 (21%)
CG10793	NP_570054.2	LisH	31..56	CDD:285685
		P-loop_NTPase	205..>259	CDD:304359	11/53 (21%)
		AAA	238..376	CDD:214640	28/131 (21%)
		AAA	242..374	CDD:278434	28/127 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0554
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900