Protein Alignment Gk1 and Fggy

DIOPT Version :10

• Sequence 1: NP_524655.1
• Gene: Gk1 / 43913
• FlyBaseID: FBgn0025592
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: NP_001013954.2
• Gene: Fggy / 298250
• RGDID: 1359429
• Length: 552
• Species: Rattus norvegicus
• Alignment Length: 574
• Identity: 129/574 - (22%)
• Similarity: 222/574 - (38%)
• Gaps: 156/574 - (27%)

  Fly    19 FVGAIDEGTTSAR-FIIFRAGTDEIVCFHQIEVESIFQKEGWCEQDPMAIVNTVNECITGACKKL 82
            :|| ||.||.|.| .::.:.|.  ::.|.:..::....:....||.        :|.|..||.::
  Rat    13 YVG-IDVGTGSVRAALVDQRGV--LLAFAEQPIKKWEPQFNHHEQS--------SEDIWAACCRV 66

  Fly    83 VAVGGKVEEIITIGITNQRE---------STVVWDR--------NSGQPLVNAIIWLDNRTTSTV 130
                  .:||:. ||...|.         |.||.|:        ..|....|.|:|||:|..|.|
  Rat    67 ------TKEIVQ-GIDAHRIRGLGFDATCSLVVLDKEFHPLPVNREGDSSRNIIMWLDHRAVSQV 124

  Fly   131 EELLETIPNNARNINYLRPLCGLPLSPYFSGVKLRWLRDNVPVVSQAMEKGTAMFGTIDTWLMYN 195
            ..:.||   ....:.|:    |..:|......||.||::|:..:  ..:|....|...| :|.:.
  Rat   125 HRINET---KHSVLQYV----GGVMSVEMQAPKLLWLKENLREI--CWDKAGHFFDLPD-FLSWK 179

  Fly   196 LTGGKDCGVHKTDVTNASRTMLMNIETLQ----WDANLLKFFGLP-----------KTILPEICS 245
            .||          ||..|...|:...|..    ||.:..|..||.           ..:||...|
  Rat   180 ATG----------VTARSLCSLVCKWTYSAEKGWDDSFWKMIGLEDLIGDNYNKIGNLVLPPGAS 234

  Fly   246 SSEFYGSIAQ-----GVLQGIGITSVLGDQQAA--------LVGQQCLAKGQAKAT-----YGT- 291
            ...  |.|.:     |:..||.:.:.|.|..|.        :.|.....:||...:     .||
  Rat   235 LGS--GLIPEAARELGLPSGIAVAASLIDAHAGGLGVIGADVRGHGLTCEGQPVTSRLAVICGTS 297

  Fly   292 GCFLLYNTGPSIVHSTHGLLTTVGYQLGRKAVP-FYALEGSVSIAG------------------- 336
            .|.:..:..|..|....|...:.       .|| |:..||..|:.|
  Rat   298 SCHMGISKDPIFVPGVWGPYFSA-------MVPGFWLNEGGQSVTGKLIDHMVQSHPAFPELQAK 355

  Fly   337 ------AAFNWLRDNMNLIQNSGQIETMASTVDNSLDVYFVPAFNGLYAPYWNQDARGVICGLSE 395
                  :.:.:|..:::||:.:..:..:      ::|::..|.|:|..:|..:...:|::.||:.
  Rat   356 ATARCQSIYAYLNSHLDLIKKAQPVGFL------TVDLHVWPDFHGNRSPLADLTLKGMVTGLTL 414

  Fly   396 ETTSEHIV---RATLEAVCFQVRDILDSM----HKDCKIPLAKLMVDGGMTVNNLFLQLQSDLVG 453
            ....:.:.   .||::|:.|..|.|:::|    |.     |:.|.:.||::.|.||:|:.:|:.|
  Rat   415 SRDLDDLAVLYLATIQAIAFGTRFIIETMEAAGHS-----LSTLFLCGGLSKNPLFVQMHADITG 474

  Fly   454 IQVLRAKIAETTALGAAMAA------YKAVENRYQMEAPLSKSG----PREAIK 497
            :.|:.::..|:..:|||:..      :.:|:   :..|.:||.|    |..|.|
  Rat   475 MPVVLSQEVESVLVGAAILGACASGDFASVQ---EAMARMSKVGKVVFPERADK 525

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gk1	NP_524655.1	ASKHA_NBD_FGGY_GK1-3-like	18..519	CDD:466802	129/574 (22%)
Fggy	NP_001013954.2	ASKHA_NBD_FGGY_D-RBK	12..545	CDD:466800	129/574 (22%)