Protein Alignment Gk1 and SHPK

DIOPT Version :9

• Sequence 1: NP_524655.1
• Gene: Gk1 / 43913
• FlyBaseID: FBgn0025592
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: NP_037408.2
• Gene: SHPK / 23729
• HGNCID: 1492
• Length: 478
• Species: Homo sapiens
• Alignment Length: 548
• Identity: 105/548 - (19%)
• Similarity: 182/548 - (33%)
• Gaps: 174/548 - (31%)

  Fly    18 PFVGAIDEGTTSARFIIFRAGTDEIVCF-----------HQIEVESIFQKEGWCEQDPMAIVNTV 71
            |....||.||||.:..:.||..|:...|           .:..|||........|||...|:..:
Human     5 PITLGIDLGTTSVKAALLRAAPDDPSGFAVLASCARAARAEAAVESAVAGPQGREQDVSRILQAL 69

  Fly    72 NECITGACKKLVAVGGKVEEIITIGITNQRESTVVWDRNSG--------------QPLVNAIIWL 122
            :||:....:.      ::..::.||::.|....|.|....|              :.:.:.:.|.
Human    70 HECLAALPRP------QLRSVVGIGVSGQMHGVVFWKTGQGCEWTEGGITPVFEPRAVSHLVTWQ 128

  Fly   123 DNRTTSTVEELLETIPNNARNINYLRPLCGLPLSPYFSGVKLRWLRDNVPVVSQAMEKGTAMFGT 187
            |.|.:|   |.|.::|         :|...|.::..|....:.||....|...::.:..    ||
Human   129 DGRCSS---EFLASLP---------QPKSHLSVATGFGCATIFWLLKYRPEFLKSYDAA----GT 177

  Fly   188 IDTWLMYNLTGGKDCGVHKTDVT--NASRTMLMNIETLQWDANLLKFFGLPKTILPEICS----- 245
            |..:::..|     ||:.:..::  ||:.....|.::..|:...|:..|.|..:||:|..
Human   178 IHDYVVAML-----CGLPRPLMSDQNAASWGYFNTQSQSWNVETLRSSGFPVHLLPDIAEPGSVA 237

  Fly   246 --SSEFYGSIAQGVLQGIGITSVLGDQQAALVGQQCLAKGQAKATYGTGCFLLYNTGPSIVHSTH 308
              :|..:..|.:|...|:    .|||.||::  ..|:|:       .|...|..:|...:..|..
Human   238 GRTSHMWFEIPKGTQVGV----ALGDLQASV--YSCMAQ-------RTDAVLNISTSVQLAASMP 289

  Fly   309 GLLTTVGYQLGRKAVPFYALEGSVSIAGAAFNWLRDNMNLIQNSGQIETMASTVDNSLDVYFVPA 373
            .     |:|                                        .|.|.|.:..|
Human   290 S-----GFQ----------------------------------------PAQTPDPTAPV----- 304

  Fly   374 FNGLYAPYWNQDARGVICGLS------------------------EETTSEHIVRA--------- 405
               .|.||:|:...||...|:                        |.|....:::|
Human   305 ---AYFPYFNRTYLGVAASLNGGNVLATFVHMLVQWMADLGLEVEESTVYSRMIQAAVQQRDTHL 366

  Fly   406 TLEAVCFQVRDILDSMHKDCKIPLAKLMVDGGMT-------VNNLFLQLQSDLVGIQVLRA-KIA 462
            |:.......|.:.|.:....:|..:.|.: |.:|       |.||     ..::.||.|:. .:.
Human   367 TITPTVLGERHLPDQLASVTRISSSDLSL-GHVTRALCRGIVQNL-----HSMLPIQQLQEWGVE 425

  Fly   463 ETTALGAAMAAYKAVENRYQMEAPLSKS 490
            .....|:|::....::...|...||..|
Human   426 RVMGSGSALSRNDVLKQEVQRAFPLPMS 453

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gk1	NP_524655.1	glycerol_kin	18..522	CDD:273549	105/548 (19%)
		FGGY_GK1-3_metazoa	18..522	CDD:212664	105/548 (19%)
SHPK	NP_037408.2	FGGY_SHK_like	5..468	CDD:212661	105/548 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0554
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810