Protein Alignment Gk1 and Gk

DIOPT Version :9

• Sequence 1: NP_524655.1
• Gene: Gk1 / 43913
• FlyBaseID: FBgn0025592
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: XP_006527892.1
• Gene: Gk / 14933
• MGIID: 106594
• Length: 587
• Species: Mus musculus
• Alignment Length: 556
• Identity: 281/556 - (50%)
• Similarity: 366/556 - (65%)
• Gaps: 41/556 - (7%)

  Fly    17 GPFVGAIDEGTTSARFIIFRAGTDEIVCFHQIEVESIFQKEGWCEQDPMAIVNTVNECITGACKK 81
            ||.|||:|:||:|.||::|.:.|.|::..||:|::..|.:|||.||||..|:.:|.|||...|:|
Mouse    10 GPLVGAVDQGTSSTRFLVFNSKTAELLSHHQVEIKQEFPREGWVEQDPKEILQSVYECIEKTCEK 74

  Fly    82 LVAVGGKVEEIITIGITNQRESTVVWDRNSGQPLVNAI--------------------------- 119
            |..:...:..|..||::||||:|||||:.:|:||.||:
Mouse    75 LGQLNIDISNIKAIGVSNQRETTVVWDKVTGEPLYNAVAAPVSPGSSVPVAVVPSGSSVPAAGAS 139

  Fly   120 -IWLDNRTTSTVEELLETIPNNARNINYLRPLCGLPLSPYFSGVKLRWLRDNVPVVSQAMEKGTA 183
             :|||.||.||||.|.:.||.|.   |:::...|||||.|||.||||||.|||..|.:|:|:..|
Mouse   140 SVWLDLRTQSTVENLSKRIPGNN---NFVKSKTGLPLSTYFSAVKLRWLLDNVKKVQEAVEENRA 201

  Fly   184 MFGTIDTWLMYNLTGGKDCGVHKTDVTNASRTMLMNIETLQWDANLLKFFGLPKTILPEICSSSE 248
            :|||||:||:::||||...|||.|||||||||||.||.:|:||..|.:|||:|..|||.:.||||
Mouse   202 LFGTIDSWLIWSLTGGIHGGVHCTDVTNASRTMLFNIHSLEWDKELCEFFGIPMEILPNVRSSSE 266

  Fly   249 FYG------SIAQGVLQGIGITSVLGDQQAALVGQQCLAKGQAKATYGTGCFLLYNTGPSIVHST 307
            .||      |:..|.|:|:.|:..||||.||||||.|...||||.|||||||||.|||...|.|.
Mouse   267 IYGLMKISHSLKAGALEGVPISGCLGDQSAALVGQMCFQDGQAKNTYGTGCFLLCNTGHKCVFSE 331

  Fly   308 HGLLTTVGYQLGRKAVPFYALEGSVSIAGAAFNWLRDNMNLIQNSGQIETMASTVDNSLDVYFVP 372
            |||||||.|:|||....:|||||||:||||...|||||:.:|::|.:||.:|..|..|...||||
Mouse   332 HGLLTTVAYKLGRDKPVYYALEGSVAIAGAVIRWLRDNLGIIKSSEEIEKLAKEVGTSYGCYFVP 396

  Fly   373 AFNGLYAPYWNQDARGVICGLSEETTSEHIVRATLEAVCFQVRDILDSMHKDCKIPLAKLMVDGG 437
            ||:|||||||...|||:||||::.|...||..|.|||||||.|:|||:|::||.|||:.|.||||
Mouse   397 AFSGLYAPYWEPSARGIICGLTQFTNKCHIAFAALEAVCFQTREILDAMNRDCGIPLSHLQVDGG 461

  Fly   438 MTVNNLFLQLQSDLVGIQVLRAKIAETTALGAAMAAYKAVE--NRYQMEAPLSKSGPREAIKPSI 500
            ||.|.:.:|||:|::.|.|::..:.||||||||||| .|.|  ..:.:|.....:...|..:|.|
Mouse   462 MTSNKILMQLQADILYIPVVKPSMPETTALGAAMAA-GAAEGVGVWSLEPEDLSAVTMERFEPQI 525

  Fly   501 SATDRNLRYQKWKMAIDRSLNWETSTLPQ-GEREAF 535
            :|.:..:||..||.|:.:|:.|.|:..|: |:...|
Mouse   526 NAEESEIRYSTWKKAVMKSIGWVTTQSPESGDPSIF 561

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gk1	NP_524655.1	glycerol_kin	18..522	CDD:273549	275/539 (51%)
		FGGY_GK1-3_metazoa	18..522	CDD:212664	275/539 (51%)
Gk	XP_006527892.1	FGGY_GK1-3_metazoa	11..547	CDD:212664	275/539 (51%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167833652
Domainoid	1	1.000	292	1.000	Domainoid score	I1512
eggNOG	1	0.900	-	-		E1_COG0554
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H134743
Inparanoid	1	1.050	566	1.000	Inparanoid score	I1070
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG60628
OrthoDB	1	1.010	-	-		D352321at33208
OrthoFinder	1	1.000	-	-		FOG0001035
OrthoInspector	1	1.000	-	-		otm42844
orthoMCL	1	0.900	-	-		OOG6_100613
Panther	1	1.100	-	-	O	PTHR10196
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2135
SonicParanoid	1	1.000	-	-		X1107
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	16	15.800