Protein Alignment Gk1 and Gk2

DIOPT Version :10

• Sequence 1: NP_524655.1
• Gene: Gk1 / 43913
• FlyBaseID: FBgn0025592
• Length: 538
• Species: Drosophila melanogaster
• Sequence 2: NP_034424.1
• Gene: Gk2 / 14626
• MGIID: 1329027
• Length: 554
• Species: Mus musculus
• Alignment Length: 525
• Identity: 280/525 - (53%)
• Similarity: 368/525 - (70%)
• Gaps: 7/525 - (1%)

  Fly    14 TLSGPFVGAIDEGTTSARFIIFRAGTDEIVCFHQIEVESIFQKEGWCEQDPMAIVNTVNECITGA 78
            |.:||.|||:.:||.|.||::|.:.|.|:||.||:|:...:.||||.||||..|:.:|.|||..|
Mouse     7 TSAGPLVGAVVQGTNSTRFLVFNSKTAELVCSHQVELTQEYPKEGWVEQDPKEILKSVYECIAKA 71

  Fly    79 CKKLVAVGGKVEEIITIGITNQRESTVVWDRNSGQPLVNAIIWLDNRTTSTVEELLETIPNNARN 143
            |:||..|...:..|..||::||||:|||||:.:|.||.||::|||.||.||||.|.:.||.|:
Mouse    72 CEKLAEVNIDISNIKAIGVSNQRETTVVWDKFTGDPLYNAVVWLDLRTQSTVETLTKKIPGNS-- 134

  Fly   144 INYLRPLCGLPLSPYFSGVKLRWLRDNVPVVSQAMEKGTAMFGTIDTWLMYNLTGGKDCGVHKTD 208
             |:::...|||||.|||.|||||:.||:..:.:|:|:|.|||||||:||::.:|||.:.|:|.||
Mouse   135 -NFVKSKTGLPLSTYFSAVKLRWMLDNLRPIQKAVEEGRAMFGTIDSWLIWCMTGGVNGGIHCTD 198

  Fly   209 VTNASRTMLMNIETLQWDANLLKFFGLPKTILPEICSSSEFYGSIAQGVLQGIGITSVLGDQQAA 273
            ||||.||||.||.:|:||.:|..||.:|.:|||.:|||||.||.:..|.|:|:.|:..||||.||
Mouse   199 VTNACRTMLFNIHSLEWDKDLCDFFEIPMSILPNVCSSSEIYGLMTSGALEGVPISGCLGDQSAA 263

  Fly   274 LVGQQCLAKGQAKATYGTGCFLLYNTGPSIVHSTHGLLTTVGYQLGRKAVPFYALEGSVSIAGAA 338
            ||||.|..:||||.|||||||||.|||...|.|.||||||:.|:||:....||||||||:||||.
Mouse   264 LVGQMCFHEGQAKNTYGTGCFLLCNTGQKCVFSEHGLLTTLAYKLGKNKPVFYALEGSVAIAGAV 328

  Fly   339 FNWLRDNMNLIQNSGQIETMASTVDNSLDVYFVPAFNGLYAPYWNQDARGVICGLSEETTSEHIV 403
            ..|||||..:|..||::|.:|..|..|...||||||:|||||||...|||:||||::.|...||.
Mouse   329 IRWLRDNFEIITTSGEVENLAREVGTSYGCYFVPAFSGLYAPYWEPSARGIICGLTQFTNKCHIA 393

  Fly   404 RATLEAVCFQVRDILDSMHKDCKIPLAKLMVDGGMTVNNLFLQLQSDLVGIQVLRAKIAETTALG 468
            .|.|||||||.|:|||:|::||.|||:.|.||||||.|.:.:|||:|::.|.|:::.:.||||||
Mouse   394 FAALEAVCFQTREILDAMNRDCGIPLSHLQVDGGMTNNRILMQLQADILHIPVVKSVMPETTALG 458

  Fly   469 AAMAAYKAVE--NRYQMEAPLSKSGPREAIKPSISATDRNLRYQKWKMAIDRSLNWETSTLPQ-G 530
            ||||| .|.|  |.:.:|.....:...|..:|.|.||:..:|:..||.|:.:|:.|.|:..|: |
Mouse   459 AAMAA-GAAEGVNVWSLEPEDLSTILMERYEPQIQATESEIRFSTWKRAVMKSMGWVTAKDPENG 522

  Fly   531 EREAF 535
            :...|
Mouse   523 DNPVF 527

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gk1	NP_524655.1	ASKHA_NBD_FGGY_GK1-3-like	18..519	CDD:466802	272/502 (54%)
Gk2	NP_034424.1	ASKHA_NBD_FGGY_GK1-3-like	11..510	CDD:466802	272/502 (54%)