Protein Alignment SF1 and MSL5

DIOPT Version :10

• Sequence 1: NP_524654.2
• Gene: SF1 / 43912
• FlyBaseID: FBgn0025571
• Length: 787
• Species: Drosophila melanogaster
• Sequence 2: NP_013217.1
• Gene: MSL5 / 850807
• SGDID: S000004106
• Length: 476
• Species: Saccharomyces cerevisiae
• Alignment Length: 548
• Identity: 185/548 - (33%)
• Similarity: 259/548 - (47%)
• Gaps: 120/548 - (21%)

  Fly   260 FDNSADSAAERKRKR------KSRWGGS--ENDKTFIPGMPTILPSTLDPAQQEAYLVQFQIEEI 316
            |:|...|:.|.|:.:      .|.|..:  |:|......:|:.:...|...|..:|.|.|:|:||
Yeast    11 FENRKGSSMEEKKAKVPPNVNLSLWRKNTVESDVHRFNSLPSKISGALTREQIYSYQVMFRIQEI 75

  Fly   317 SRKLRTGDLGITQNPEERSPSPEPIYSSDGKRLNTREFRYRKRLEEQRHQLI-VKMQTVNPEFKP 380
            :.||||.|. :..:.:.|||||.|:|.:.|||.||||.||||:||::|.:|: :.::|: |.|.|
Yeast    76 TIKLRTNDF-VPPSRKNRSPSPPPVYDAQGKRTNTREQRYRKKLEDERIKLVEIALKTI-PYFVP 138

  Fly   381 PADYKPPVTRVSDKVLIPQEQHPDINFVGLLIGPRGNTLKAMEKDTGAKIIIRGKGSVKEGKVGR 445
            |.|||.| |:..||..||.:|:||:||||||:||||.||:.:::|:..||.|||:||||||
Yeast   139 PDDYKRP-TKFQDKYYIPVDQYPDVNFVGLLLGPRGRTLRKLQEDSNCKIAIRGRGSVKEG---- 198

  Fly   446 KDGQPLP----GEDEPLHAFITAPNPEAVRKAVDKIKDVIRQGIEVPEGHNDLRRMQLRELAQLN 506
            |:...||    ..::|||..|.|.:.:.::|.:...::::.:.:..|||.|||:|.||||||:||
Yeast   199 KNASDLPPGAMNFEDPLHCLIIADSEDKIQKGIKVCQNIVIKAVTSPEGQNDLKRGQLRELAELN 263

  Fly   507 GTLRENDIQRCTCGSTDHKSWQCPDKPIIT-NTIVCTSCGGTGHLTKDCRNKRPGSGVPGMACED 570
            |||||::.....||..|||.:.||::.|.. ..|||..||.|||.::||     .|....|:..|
Yeast   264 GTLREDNRPCPICGLKDHKRYDCPNRKIPNIQGIVCKICGQTGHFSRDC-----NSSSQRMSRFD 323

  Fly   571 SQAKIDEE--YMSLMAELGEGPPPPSASAK-------TDPPASNGPQLHRASYSIFDKKPSQMQA 626
            ..|.::..  ..|..........|..|..:       |:||      |...:.|.:...|
Yeast   324 RNATVNNSAPIQSNDVHYNSNTHPIQAPKRSRYDNNSTEPP------LKFPASSRYAPSP----- 377

  Fly   627 IQSPPSSS-SRDHQRDLGGWGAAAHEHGMGMEHGMGLDQHGHGLAAMDHGMSLGMEHAMAAYVPA 690
              |||:|. ||..|.                                              ..|.
Yeast   378 --SPPASHISRQAQN----------------------------------------------VTPT 394

  Fly   691 PP--------GTQAPPPMPPPLMPWMSAPQPPPPATEP--LNPPIPG--TLPPLIPPPPGTSAPP 743
            ||        .:..|...||||       |.||.:.:|  ..||.||  |:...|.||||.|.||
Yeast   395 PPPGLTSSSFSSGVPGIAPPPL-------QSPPESEQPKFSLPPPPGMTTVQSSIAPPPGLSGPP 452

  Fly   744 MPPWGGGAYSGWGGGYAPPPPPPCAPPP 771
                  |..:..|.....|.||....||
Yeast   453 ------GFSNNMGNDINKPTPPGLQGPP 474

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SF1	NP_524654.2	MSL5	253..512	CDD:227503	114/264 (43%)
		PTZ00368	<519..>568	CDD:173561	20/49 (41%)
MSL5	NP_013217.1	MSL5	1..269	CDD:227503	114/264 (43%)
		AIR1	<267..386	CDD:227414	37/136 (27%)
		PHA03247	<363..435	CDD:223021	27/137 (20%)