Protein Alignment SF1 and SF1

DIOPT Version :9

• Sequence 1: NP_524654.2
• Gene: SF1 / 43912
• FlyBaseID: FBgn0025571
• Length: 787
• Species: Drosophila melanogaster
• Sequence 2: NP_001365886.1
• Gene: SF1 / 7536
• HGNCID: 12950
• Length: 764
• Species: Homo sapiens
• Alignment Length: 678
• Identity: 290/678 - (42%)
• Similarity: 355/678 - (52%)
• Gaps: 203/678 - (29%)

  Fly   234 GNAGGNKGFASFFNSQNSNDSTSNGAFDNSADSAAERKRKRKSRWG-GSENDKTFIPGMPTILPS 297
            |.|||...|.|                          |::::|||. .:...||.||||||::|.
Human   129 GPAGGGGDFPS--------------------------KKRKRSRWNQDTMEQKTVIPGMPTVIPP 167

  Fly   298 TLDPAQQEAYLVQFQIEEISRKLRTGDLGITQNPEERSPSPEPIYSSDGKRLNTREFRYRKRLEE 362
            .|...|:.||:||.|||:::||||||||||..|||:|||||||||:|:||||||||||.||:|||
Human   168 GLTREQERAYIVQLQIEDLTRKLRTGDLGIPPNPEDRSPSPEPIYNSEGKRLNTREFRTRKKLEE 232

  Fly   363 QRHQLIVKMQTVNPEFKPPADYKPPVTRVSDKVLIPQEQHPDINFVGLLIGPRGNTLKAMEKDTG 427
            :||.||.:|..:||:||||||||||.|||||||:|||:::|:||||||||||||||||.:||:..
Human   233 ERHNLITEMVALNPDFKPPADYKPPATRVSDKVMIPQDEYPEINFVGLLIGPRGNTLKNIEKECN 297

  Fly   428 AKIIIRGKGSVKEGKVGRKDGQPLPGEDEPLHAFITAPNPEAVRKAVDKIKDVIRQGIEVPEGHN 492
            |||:||||||||||||||||||.||||||||||.:||...|.|:|||::|:::::||||.||..|
Human   298 AKIMIRGKGSVKEGKVGRKDGQMLPGEDEPLHALVTANTMENVKKAVEQIRNILKQGIETPEDQN 362

  Fly   493 DLRRMQLRELAQLNGTLRENDIQRCTCGSTDHKSWQCPDKPIITNTIVCTSCGGTGHLTKDCRNK 557
            |||:|||||||:|||||||:|       :...:.||..:...||||.|||.|||.||:..||:.:
Human   363 DLRKMQLRELARLNGTLREDD-------NRILRPWQSSETRSITNTTVCTKCGGAGHIASDCKFQ 420

  Fly   558 RPGSGVPGMACEDSQAKIDEEYMSLMAELGEGPPPPSASAKTDP-------------PASNGPQL 609
            |||.  |..|  ..:|::|:||:||||||||.|.|.|..:.:.|             ||:|.|
Human   421 RPGD--PQSA--QDKARMDKEYLSLMAELGEAPVPASVGSTSGPATTPLASAPRPAAPANNPP-- 479

  Fly   610 HRASYSIFDKKPSQMQAIQSPP------SSSSRD----HQRDLGGWGAAAHEHGMGMEHGMGLDQ 664
                      .||.|...||.|      .|.||.    |....||.|...|    ...|.:....
Human   480 ----------PPSLMSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPH----SFPHPLPSLT 530

  Fly   665 HGHGLAAMDHG---------------MSLGMEHAMAAYVPAPPGTQAPPP--------------- 699
            .|||...|.|.               |:.|         |.|||...|||
Human   531 GGHGGHPMQHNPNGPPPPWMQPPPPPMNQG---------PHPPGHHGPPPMDQYLGSTPVGSGVY 586

  Fly   700 --------MPPPLMPWMSAP------QPPPPATEPLNP----------------------PIP-- 726
                    ||||.|..|..|      |||||.:.||.|                      |:|
Human   587 RLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQ 651

  Fly   727 ------------GTLPP----------------------LIPPPPGTSAPPMPPWGGGAYSGWGG 757
                        |::||                      ::|.|||.. ||:||.
Human   652 QNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQ-PPLPPG---------- 705

  Fly   758 GYAPPPPPPCAPPPPALSLSQPPPPPPP 785
              |||||||  |||.:..:...||||||
Human   706 --APPPPPP--PPPGSAGMMYAPPPPPP 729

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SF1	NP_524654.2	MSL5	253..512	CDD:227503	168/259 (65%)
		SF1-HH	274..385	CDD:292892	72/111 (65%)
		SF1_like-KH	392..510	CDD:239088	86/117 (74%)
SF1	NP_001365886.1	MSL5	142..382	CDD:227503	148/240 (62%)
		ZnF_C2HC	403..418	CDD:197667	5/14 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165160022
Domainoid	1	1.000	158	1.000	Domainoid score	I4125
eggNOG	1	0.900	-	-		E1_COG5176
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	475	1.000	Inparanoid score	I1499
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52021
OrthoDB	1	1.010	-	-		D367566at33208
OrthoFinder	1	1.000	-	-		FOG0003999
OrthoInspector	1	1.000	-	-		oto88359
orthoMCL	1	0.900	-	-		OOG6_102013
Panther	1	1.100	-	-	LDO	PTHR11208
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R128
SonicParanoid	1	1.000	-	-		X2762
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	15	14.800