Protein Alignment SF1 and Sf1

DIOPT Version :10

• Sequence 1: NP_524654.2
• Gene: SF1 / 43912
• FlyBaseID: FBgn0025571
• Length: 787
• Species: Drosophila melanogaster
• Sequence 2: NP_001104261.1
• Gene: Sf1 / 22668
• MGIID: 1095403
• Length: 639
• Species: Mus musculus
• Alignment Length: 641
• Identity: 284/641 - (44%)
• Similarity: 349/641 - (54%)
• Gaps: 177/641 - (27%)

  Fly   271 KRKRKSRWG-GSENDKTFIPGMPTILPSTLDPAQQEAYLVQFQIEEISRKLRTGDLGITQNPEER 334
            |::::|||. .:...||.||||||::|..|...|:.||:||.|||:::||||||||||..|||:|
Mouse    15 KKRKRSRWNQDTMEQKTVIPGMPTVIPPGLTREQERAYIVQLQIEDLTRKLRTGDLGIPPNPEDR 79

  Fly   335 SPSPEPIYSSDGKRLNTREFRYRKRLEEQRHQLIVKMQTVNPEFKPPADYKPPVTRVSDKVLIPQ 399
            ||||||||:|:||||||||||.||:|||:||.||.:|..:||:||||||||||.|||||||:|||
Mouse    80 SPSPEPIYNSEGKRLNTREFRTRKKLEEERHTLITEMVALNPDFKPPADYKPPATRVSDKVMIPQ 144

  Fly   400 EQHPDINFVGLLIGPRGNTLKAMEKDTGAKIIIRGKGSVKEGKVGRKDGQPLPGEDEPLHAFITA 464
            :::|:||||||||||||||||.:||:..|||:||||||||||||||||||.||||||||||.:||
Mouse   145 DEYPEINFVGLLIGPRGNTLKNIEKECNAKIMIRGKGSVKEGKVGRKDGQMLPGEDEPLHALVTA 209

  Fly   465 PNPEAVRKAVDKIKDVIRQGIEVPEGHNDLRRMQLRELAQLNGTLRENDIQRCTCGSTDHKSWQC 529
            ...|.|:|||::|:::::||||.||..||||:|||||||:|||||||:|       :...:.||.
Mouse   210 NTMENVKKAVEQIRNILKQGIETPEDQNDLRKMQLRELARLNGTLREDD-------NRILRPWQS 267

  Fly   530 PDKPIITNTIVCTSCGGTGHLTKDCRNKRPGSGVPGMACEDSQAKIDEEYMSLMAELGEGPPPPS 594
            .:...||||.|||.|||.||:..||:.:|||.  |..|  ..:|::|:||:||||||||.|.|.|
Mouse   268 SETRSITNTTVCTKCGGAGHIASDCKFQRPGD--PQSA--QDKARMDKEYLSLMAELGEAPVPAS 328

  Fly   595 ASAKTDP-------------PASNGPQLHRASYSIFDKKPSQMQAIQSPP------SSSSRD--- 637
            ..:.:.|             ||||.|            .||.|...||.|      .|.:|.
Mouse   329 VGSTSGPATTPLASAPRPAAPASNPP------------PPSLMSTTQSRPPWMNSGPSENRPYHG 381

  Fly   638 -HQRDLGGWGAAAHEHGMGMEHGMGLDQHGHGLAAMDHG---------------MSLGMEHAMAA 686
             |....||.|...|    ...|.:.....|||...|.|.               |:.|
Mouse   382 MHGGGPGGPGGGPH----SFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQG------- 435

  Fly   687 YVPAPPGTQAPPP-----------------------MPPPLMPWMSAP------QPPPPATEPLN 722
              |.|||...|||                       ||||.|..|..|      |||||.:.||.
Mouse   436 --PHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLP 498

  Fly   723 P----------------------PIP--------------GTLPP-------------------- 731
            |                      |:|              |::||
Mouse   499 PWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGTPQMQGN 563

  Fly   732 --LIPPPPGTSAPPMPPWGGGAYSGWGGGYAPPPPPPCAPPPPALSLSQPPPPPPP 785
              ::|.|||.. ||:||.            |||||||  |||.:..:...||||||
Mouse   564 PTMVPLPPGVQ-PPLPPG------------APPPPPP--PPPGSAGMMYAPPPPPP 604

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SF1	NP_524654.2	MSL5	253..512	CDD:227503	168/241 (70%)
		PTZ00368	<519..>568	CDD:173561	20/48 (42%)
Sf1	NP_001104261.1	MSL5	17..257	CDD:227503	167/239 (70%)
		ZnF_C2HC	278..293	CDD:197667	9/14 (64%)