Protein Alignment syd and si:dkey-17m8.1

DIOPT Version :9

• Sequence 1: NP_524652.1
• Gene: syd / 43905
• FlyBaseID: FBgn0024187
• Length: 1227
• Species: Drosophila melanogaster
• Sequence 2: XP_009290487.2
• Gene: si:dkey-17m8.1 / 796618
• ZFINID: ZDB-GENE-110411-225
• Length: 985
• Species: Danio rerio
• Alignment Length: 1219
• Identity: 310/1219 - (25%)
• Similarity: 510/1219 - (41%)
• Gaps: 301/1219 - (24%)

  Fly    41 IVQQLAGSIYQEFERMINRYDEDVVKNLMPLLVNVLECLDASYRIN-QEQDVEVELLREDNEQLV 104
            ||.:.||.:|.|.:.::..:..|||::|:|:||.|||.| ||.|.. :|::...|..:.:.|:|:
Zfish    19 IVSEEAGKLYSELQSVVETHGADVVESLLPILVWVLEGL-ASCRAQLREREETSEKEKGEREELL 82

  Fly   105 TQYEREKSARKQSEQKLLEAEDLAEQENKELATRLESVESIVRMLELKHKNSLEHASRLEEREAD 169
            .:|:.||:.|:||:::.||.:|..|||.:.:.:|....|...|.||.|.:...:....|||::::
Zfish    83 DRYQSEKTLRRQSQERYLELDDQFEQERRAMRSRENEREKRERELEKKAREQADQLMALEEQKSN 147

  Fly   170 LKKEYNKLHERYTELFKNHVDYMERTK-------MLMGSTHSQMSTA---SERMDVSRARLN-PV 223
            |.:|.|.|...:.:|...|.|.:|:.|       ......||:.|.|   ..:.|.|.:..: |.
Zfish   148 LSRELNSLKHTHNKLVLTHRDLLEKKKEWESEASAFRNHVHSKYSEAVSNQGQTDTSSSEEHCPE 212

  Fly   224 ARS----------------SGPVSYGFASLENSVMLDTETICSVGSQSDDSGPPSLQNELDNLSG 272
            |.|                ...|::...|..:.::..|..:..:....:.|.|..|:.....::.
Zfish   213 AGSVNDSTSTTITNDNKVTDAEVNHNNESFISEIISSTPELAHLKKCVETSTPVCLKTMTSEINS 277

  Fly   273 TLERGAATDALQQQHHATSPQSPDSSPVVPNVPTNVGRSTTKKEQRSDNN-LYQELSFQDNEESE 336
            :|     .|.::|.....:.:..|..       ..||..|..:...:|:: |..:|...|:..||
Zfish   278 SL-----FDEIKQDPEDKNEEDGDQK-------LKVGEKTNVETMENDSDCLEYQLRNTDSVFSE 330

  Fly   337 ENEIVTGSWVHPGEYASSANDNYFGMGKEVENLIMENNELLATKNALNIVKDDLIVKVDELTGEV 401
            .:|: :..:|...:..:|..|:    ..:.|.::.:..||..:...::..:..||.:|:|||.|.
Zfish   331 LSEL-SRDYVENVDKGASVRDS----SDQFEQILSQYEELKCSHEMVDTARKALISRVEELTNER 390

  Fly   402 EIVREELNAMQQSRTKLRQRISELEDELKKAKEQVKQQNTEQEENDVPLAQRKRFTRVEMAMVLM 466
            ..:..||.:.:::.|:...:|.|:|:|.|:.:::::...:|..:...|.:.| ||:|.|||.|:|
Zfish   391 SALNLELVSCRETITRFEGKIKEMEEESKRLQKELEMFQSENPDASTPTSLR-RFSRSEMARVVM 454

  Fly   467 ERNQYKERLMELQEAVRLTEILRASRTVDNLDRKSKQSIWKYFSNLFTPSNRPTERVADGLGGGP 531
            |:|||||||.|||||||.::.|:.::. ::...:.|.|:|..|:...            ||
Zfish   455 EKNQYKERLFELQEAVRRSQTLKVTKE-EHPPVEGKGSVWSRFNRFL------------GL---- 502

  Fly   532 MFRHTGGGSPAHSHGSPSRGSGGGDNRLALT-SGQPPVHPASAGLANALIMPKDYAEEGSSERIS 595
                             ::|..|....||:| |..|....|.||....|.......|..||.|:
Zfish   503 -----------------TKGQLGPATALAVTMSSTPAPAQAPAGSPKHLSTKPPQTENSSSPRL- 549

  Fly   596 ARRREQYRQLRAHVQKEDGRLHAYGWSLP--INKASQEANPNRHSGGVPVPVYCNPLAEASPHMK 658
             |:||.||::|:||....|:...:|||:|  |....|...|......||:.:....|.:.....|
Zfish   550 -RKRELYREIRSHVWGTLGKKQLHGWSMPLAITNIKQNFEPLPEPKDVPILIQLRLLDQRDATAK 613

  Fly   659 VFCAAGVNLHGGFTKNGQSLIPANSPYAPKSTLKIAEITSPTADQSMEALDRQMARVSLETLEPE 723
            :.||..|                                                       .||
Zfish   614 LTCAVAV-------------------------------------------------------PPE 623

  Fly   724 T--QLSSFVWICTSTHAASTVSVVDANQSATVLDAFPI-CASHLLCIASVQGAMESDYALLEQSE 785
            .  :.:..||..|...::|.|:|:|..:|.|:||.|.: ..|..|||.:|
Zfish   624 ISGEQTCSVWAVTGPASSSDVTVIDPARSNTILDQFSLPPTSPALCICAV--------------- 673

  Fly   786 VVKAGEMLQRPGEGTELLGKVEFVRVKPKSDDEQNSNEKQQQEEEEAKEATEKSNEQLPAVSAEE 850
                                                                            .
Zfish   674 ----------------------------------------------------------------P 674

  Fly   851 PLGNVEAIKIRQPLPGAPQRLSTDGNQTNNNNNSSSSSNLLFATKSLNPILETKDRDEPAMSSVG 915
            |.||                                                          ::|
Zfish   675 PTGN----------------------------------------------------------TLG 681

  Fly   916 PTMWLGAQDGWLYVHSSVGRWHECLHRVLLPDAVLAIVHVEARVVVALANAQLAVFRRQTDGQWD 980
             |:|:|.|||.:.:|||......||..|.|.:.|.::.:.:..||..||:..| ||.....|.||
Zfish   682 -TVWIGTQDGGVLIHSSSSSRRHCLQSVNLSEGVHSLTYSQDEVVAGLADGTL-VFFSHNSGMWD 744

  Fly   981 LNSYHLVTLGDRN-HSIRCLCVAGER-IWAAHRNKIFIVDPVSLNIVHSLDAHPRKESQVRQMAA 1043
            |.|:.:::|.... ..||| |:|.|. :|..:.||::::......|..|.....|.|.|||.:.|
Zfish   745 LQSHEVLSLDTPPLQPIRC-CLAKEGCLWVGYWNKVYMISAKQRKIQKSFSVSERNEQQVRFLCA 808

  Fly  1044 TGAGVWVSIRLDSTLRLYNTHTFEHKQDVDIEPYVSKMLGTGKLGFSFVRITALMVSCNRLWIGT 1108
            .|:|||.|.||||.|||::..|....|:||:...|:|.||:..|..|.::|||:.|...|||:||
Zfish   809 AGSGVWASCRLDSILRLFDWTTGRPLQEVDLSSMVTKALGSAFLSLSPLQITAMSVVSGRLWVGT 873

  Fly  1109 SNGVIISVPLAEVQPKSSSDPHGQMPLCCMANAQLSFHGHRDAVKFFVSVPMLQQPNLNGGLTFT 1173
            .:|.:.|:||:......|      :|.|.:|:|||.:||||.||||.:|.|.....:.:.....|
Zfish   874 GSGAVFSIPLSLTSESCS------IPYCSLASAQLCYHGHRQAVKFIISAPGCYSASNSADGAAT 932

  Fly  1174 NKRPDMLVMCGGEGYIDFRINDNDMENSIQLEPNQTIENRGDKSYLIVW 1222
            :.:   |::.||||||:|||.|:..:.:     ::.:..|.::|::|:|
Zfish   933 SSQ---LILSGGEGYINFRIGDDGSDGA-----SEYVLQRSERSHMIIW 973

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
syd	NP_524652.1	Jnk-SapK_ap_N	43..196	CDD:286787	51/153 (33%)
		JIP_LZII	362..430	CDD:293080	17/67 (25%)
		Vps53_N	374..>524	CDD:282020	48/149 (32%)
si:dkey-17m8.1	XP_009290487.2	Jnk-SapK_ap_N	21..174	CDD:313040	51/153 (33%)
		SMC_N	<54..>476	CDD:330553	116/440 (26%)
		JIP_LZII	352..419	CDD:318633	17/66 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170595324
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2077
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D165438at33208
OrthoFinder	1	1.000	-	-		FOG0004823
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR13886
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	7	6.810