Protein Alignment syd and spag9a

DIOPT Version :9

• Sequence 1: NP_524652.1
• Gene: syd / 43905
• FlyBaseID: FBgn0024187
• Length: 1227
• Species: Drosophila melanogaster
• Sequence 2: NP_001307217.1
• Gene: spag9a / 558833
• ZFINID: ZDB-GENE-070820-7
• Length: 1315
• Species: Danio rerio
• Alignment Length: 1407
• Identity: 558/1407 - (39%)
• Similarity: 757/1407 - (53%)
• Gaps: 278/1407 - (19%)

  Fly     2 MDNDDALLNNGGPQSGAETVYGTEDNNMVMSEKNEQVVSIVQQLAGSIYQEFERMINRYDEDVVK 66
            |:.||.::....|.:.|           ||||:       :..||.|||:||||:|.:|||||||
Zfish     1 MELDDGVVYQDDPGTSA-----------VMSER-------ISGLANSIYREFERLIRKYDEDVVK 47

  Fly    67 NLMPLLVNVLECLDASYRINQEQDVEVELLREDNEQLVTQYEREKSARKQSEQKLLEAEDLAEQE 131
            .||||:|.|||.||..:..|||.:||:|||:||||||||||||||:.||.:|::.:|.||..|||
Zfish    48 ELMPLVVAVLENLDTVFAENQEHEVELELLKEDNEQLVTQYEREKALRKHTEERFIEFEDSQEQE 112

  Fly   132 NKELATRLESVESIVRMLELKHKNSLEHASRLEEREADLKKEYNKLHERYTELFKNHVDYMERTK 196
            .|:|...|||:.|..|.||||.||..:..||||||||:||:|||.||.|:||:..|:::::||.:
Zfish   113 KKDLQNHLESLGSHSRQLELKIKNYSDQISRLEEREAELKREYNSLHLRHTEMIHNYMEHVERIR 177

  Fly   197 MLMGSTHSQMSTASERMDVSRARL-NPVARSSGPVSYGFASLENSVMLDTET------------- 247
            |     ...:..||:...:.|.|. .|::....|:|.|.:||...|....||
Zfish   178 M-----QQTVGEASDTGTMGRVRKERPLSLGIFPMSAGGSSLTPDVQGRAETPGMEGWRFNNLSH 237

  Fly   248 ---ICSVGSQSDDSGPP-------------SLQNEL-DNLSGTLERGA---------ATDALQQQ 286
               ..|:..:::|  ||             ||.|:. |.||...:.|:         |:|.....
Zfish   238 QRSNASLKLEAED--PPKKREGKDVLEAWDSLANDCKDELSDLSQGGSKSVTPMSTTASDLALDS 300

  Fly   287 HHATSPQSPDSSPV--VPNVPTNVGRSTTKKEQRSD-----------------------NNLYQE 326
            |.........::.|  ||.. .:|....|.||::||                       ....:.
Zfish   301 HREDGDAFWKNTEVQAVPGT-RSVSAGLTDKEEKSDVQAIIESTPELDMDLGYKGPSTPTRGIEN 364

  Fly   327 LSFQDNEESEENEIVTGSW-----VHPG-----EYASSA--NDNYFGMGKEVENLIMENNELLAT 379
            ::|..|.||...|:.:...     |..|     ||:..|  :.:..||.:||||||.||.:||.|
Zfish   365 MAFDRNTESLFEEVSSAGTGLIGDVDEGADLLVEYSVHALSHPSLSGMSREVENLIQENVQLLET 429

  Fly   380 KNALNIVKDDLIVKVDELTGEVEIVREELNAMQQSRTKLRQRISELEDELKKAK---EQVKQQNT 441
            |||||:||:|||.:||||:.|.|:::.||:|:.|::.||.::..|||:||||.|   |:.||.|.
Zfish   430 KNALNVVKNDLIARVDELSCEKEVLQGELDAVLQAKAKLEEKYKELEEELKKIKTETEEAKQNNN 494

  Fly   442 -EQEENDVPLAQRKRFTRVEMAMVLMERNQYKERLMELQEAVRLTEILRASRTVDNLDRKSKQSI 505
             |::|:|||.|||:||||||||.||||||||||||||||||||.||::||||....:..|.:.||
Zfish   495 KEEDESDVPTAQRRRFTRVEMARVLMERNQYKERLMELQEAVRWTEMIRASRENSEVAEKKRSSI 559

  Fly   506 WKYFSNLFTPSNRPTERVADGLGGGPMFRHTGGGSPAHSHGSPSRGSGGGDNRLALTSGQPPVHP 570
            .::||.||:.|                   :...|.:.|...||.           ....||...
Zfish   560 RQFFSRLFSSS-------------------SSAASSSSSRALPSN-----------VKYNPPSIM 594

  Fly   571 ASAGLANALIMPKDYA------EEGSSERISAR--RREQYRQLRAHVQKEDGRLHAYGWSLPINK 627
            ..:...:.....|..|      |..||..:|.|  :|.||:.::||:||||||:.|:|||||...
Zfish   595 KKSNTFSQFPREKSKAFDFLKEEVDSSGSLSRREQKRAQYQHVKAHMQKEDGRVTAHGWSLPGKY 659

  Fly   628 ASQEANPNRHSGGVPVPVYCNPLAEASPHMKVFCAAGVNLHGGFTKNGQSLIPANSPYAPKSTLK 692
            ......|..:...:||||...||.:....||:.||.||||.||      .|....|  |..||:
Zfish   660 KVANGGPVENKINLPVPVCLKPLEQKDASMKLLCATGVNLSGG------RLCDRGS--AEDSTV- 715

  Fly   693 IAEITSPTADQSMEALDRQMARVSLETLEPE---------TQLSSFVWICTSTHAASTVSVVDAN 748
                      ::..|..|:.::.||:.||.:         .::||.||||||||:::.|.|:|..
Zfish   716 ----------ETDSAKQRKGSQSSLDQLEHDPKEREQTLHVEMSSRVWICTSTHSSTKVMVIDVT 770

  Fly   749 QSATVLDAFPICASHLLCIASVQGAMESDYALLEQ-SEVVKAGE---MLQRPGEGTE-LLGKVEF 808
            :...:||:|.:|.|.:|||||:.|.:|:||...|: .:.::||.   :.....:|:| :|..|..
Zfish   771 RPDDLLDSFYVCNSCVLCIASIPGVLETDYPAGEEIPQDLEAGPDALLASSSSQGSEGVLSDVSA 835

  Fly   809 V--RVKPKSDDEQ----NSNEKQQQEE-------------------EEAKEATEKSNE------Q 842
            |  .|:..|...|    .::|:..::.                   |||.||||:..|      .
Zfish   836 VGCGVEESSLGSQAGSTGAHEQSAEQSPARGSDLSRAPSEDGLPAAEEAMEATEEDQESPGQDSS 900

  Fly   843 LPAVSAE----EPLGNVEAIKIRQPLPGAPQRLSTDGNQTNNNNNSSSSSNLLFATKSLNPILET 903
            .|.:..|    :|||...:        ||.....:......:.:::||:.......|.     ||
Zfish   901 QPGIYTEHVFTDPLGPESS--------GASAGHDSQRESDRDRDDTSSAGGKTDLAKE-----ET 952

  Fly   904 KDRDEPAMSSVGPTMWLGAQDGWLYVHSSVGRWHECLHRVLLPDAVLAIVHVEARVVVALANAQL 968
            :     .|||..||||||||:|.|||||||.||.:|||.|.|.|::|.||||:.||:||||:..|
Zfish   953 Q-----RMSSALPTMWLGAQNGCLYVHSSVARWRKCLHAVKLKDSILNIVHVKGRVLVALADGTL 1012

  Fly   969 AVFRRQTDGQWDLNSYHLVTLGDRNHSIRCLCVAGERIWAAHRNKIFIVDPVSLNIVHSLDAHPR 1033
            |:|.|..|.||||.:|||:.||..:|||||:.|..:::|..:||||:|:.|.::.|..|.|||||
Zfish  1013 AIFHRGLDSQWDLTNYHLLDLGRPHHSIRCMTVVHDKVWCGYRNKIYIIQPKAMKIERSFDAHPR 1077

  Fly  1034 KESQVRQMAATGAGVWVSIRLDSTLRLYNTHTFEHKQDVDIEPYVSKMLGTGKLGFSFVRITALM 1098
            |||||||:|..|.|:||||||||||||::.|||:|.|||||||||||||||||||||||||||||
Zfish  1078 KESQVRQLAWVGDGIWVSIRLDSTLRLFHAHTFQHLQDVDIEPYVSKMLGTGKLGFSFVRITALM 1142

  Fly  1099 VSCNRLWIGTSNGVIISVPLAEVQPKS---------------SSDPHG----------------- 1131
            |||||||:||.||||||:||::...:.               :|.|.|
Zfish  1143 VSCNRLWVGTGNGVIISIPLSDSVGQCGYLGQRAANKTVGAIASRPGGAVRVYSEDAVDGGVTGS 1207

  Fly  1132 QMPLCCMANAQLSFHGHRDAVKFFVSVPMLQQPNLNG--GLTFTNKRPD---MLVMCGGEGYIDF 1191
            .:|.|.||:|||.|||||||||||.:||  .|..:.|  |:|.:::..|   ||:|.||||||||
Zfish  1208 YVPYCSMAHAQLCFHGHRDAVKFFATVP--GQVIVPGAEGVTESSESSDGKSMLIMSGGEGYIDF 1270

  Fly  1192 RINDND-----MENSIQLEPN---QTIENRGDKSYLIVWHVS 1225
            |:.|.|     .|:....||.   |:...:.::||:|||.|:
Zfish  1271 RVGDEDGGLGRDEDEESAEPTLKLQSAPAKPERSYVIVWQVA 1312

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
syd	NP_524652.1	Jnk-SapK_ap_N	43..196	CDD:286787	92/152 (61%)
		JIP_LZII	362..430	CDD:293080	38/67 (57%)
		Vps53_N	374..>524	CDD:282020	87/153 (57%)
spag9a	NP_001307217.1	Jnk-SapK_ap_N	24..177	CDD:286787	92/152 (61%)
		JIP_LZII	412..>466	CDD:293080	32/53 (60%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170595321
Domainoid	1	1.000	567	1.000	Domainoid score	I223
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	798	1.000	Inparanoid score	I484
OMA	1	1.010	-	-		QHG49339
OrthoDB	1	1.010	-	-		D165438at33208
OrthoFinder	1	1.000	-	-		FOG0004823
OrthoInspector	1	1.000	-	-		otm25756
orthoMCL	1	0.900	-	-		OOG6_104719
Panther	1	1.100	-	-	O	PTHR13886
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2032
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	13	12.910