Protein Alignment AMPKalpha and YPL150W

DIOPT Version :9

• Sequence 1: NP_477313.1
• Gene: AMPKalpha / 43904
• FlyBaseID: FBgn0023169
• Length: 582
• Species: Drosophila melanogaster
• Sequence 2: NP_015175.1
• Gene: YPL150W / 855953
• SGDID: S000006071
• Length: 901
• Species: Saccharomyces cerevisiae
• Alignment Length: 639
• Identity: 159/639 - (24%)
• Similarity: 259/639 - (40%)
• Gaps: 158/639 - (24%)

  Fly    22 LVKIGHYLLGATLGTGTFGKVKIGEHQITRVKVAVKILNRQKIKSLDVVGKIRREIQNLKLFRHP 86
            |.::|:|.:...:|.|:||||.:..|:.|..||.:|..::..       ..|.||:...:.|..|
Yeast    35 LTEVGNYKILKQIGEGSFGKVYLALHRPTHRKVCLKTSDKND-------PNIVREVFYHRQFDFP 92

  Fly    87 HIIKLYQVISTPSDIFMIMEYVSGGELFDYIVKHGKLQEHQARRFFQQIISGVDYCHRHMIVHRD 151
            :|.|||:||.|.|.::|.:||..|.||:|:::...::...:....|.||...|.|.|....||||
Yeast    93 YITKLYEVIVTESKVWMALEYCPGKELYDHLLSLRRISLLECGELFAQISGAVYYAHSMHCVHRD 157

  Fly   152 LKPENLLLDHNMHVKIADFGLSNMMLDGEFLRTSCGSPNYAAPEVISGKLYAGPEVDIWSCGVIL 216
            ||.||:|||.|.:.|:.|||.:...:....|.|.||:..|.|||:|..:.|.|.::||||.||||
Yeast   158 LKLENILLDKNGNAKLTDFGFTRECMTKTTLETVCGTTVYMAPELIERRTYDGFKIDIWSLGVIL 222

  Fly   217 YALLCGTLPFDDEHVPTLFRKIKSGIFPIPEYLNKQVV----NLVCQMLQVDPLKRANIEEIKKH 277
            |.|:.|.|||||:.......||   :...|:|..|.:.    :|:.::|..:|.:|.::.::.:|
Yeast   223 YTLITGYLPFDDDDEAKTKWKI---VNEEPKYDAKVIPDDARDLISRLLAKNPGERPSLSQVLRH 284

  Fly   278 EWFQKDLPAYL----------------FPSSIEQ------DSNVIDTYAVAEVCTK--------- 311
            .:.|......|                |.|.:|:      ..:.:||.|:.:...|
Yeast   285 PFLQPYGSVVLDQTQKILCRQRSGGTQFKSKLERRLLKRLKQSGVDTQAIKQSILKKKCDSLSGL 349

  Fly   312 -----------------------FGVK---ETEVHNSL--LSGD---PHDQLAIAYHLI------ 339
                                   ..||   |:..||..  :|.|   |..:|:.|..|.
Yeast   350 WLLLLAQGKKQENCKYPKRSRSVLSVKKVIESATHNDTNGISEDVLKPSLELSRAASLSKMLNKG 414

  Fly   340 ---------IDNKRFADDAA---------------------------NQINEINNFFVAGSPPPP 368
                     :..|:..|.|.                           |.:.::::||.:
Yeast   415 SDFVTSMTPVSRKKSKDSAKVLNPTLSKISSQRAYSHSIAGSPRKSNNFLQKVSSFFKS------ 473

  Fly   369 PPPPVPQSSMDHQAPLATVTVGGGTSASSGTATPVPPVAGGTPSSTIPIRPHPERIAPMRDRQLA 433
                 .:||..:........|.....||:          .|.|||...::.:...|...|...:|
Yeast   474 -----KKSSNSNSNNSIHTNVSESLIASN----------RGAPSSGSFLKKNSGSIQKSRTDTVA 523

  Fly   434 MSVQTSGGGAFPEKTARGGTPIKRAKWHLGIRS-QSKPNDIMLEVYRAMKALSYEWKIINPYHVR 497
            ...:|...|:..|..|  |..:.|:..:..:.: ::..|:|.|:|  |.:.|..|       |:|
Yeast   524 NPSRTESIGSLNENVA--GAIVPRSANNTTLENKKTSGNEIGLKV--APELLLNE-------HIR 577

  Fly   498 VRRQNVKTGKFSKMSLQLYQVDAKSYLLDFKSLTNDEVEQGDDVIMESLTPPPL 551
            :....:|..| |.:|.::.|....:|  |.:|..|......|.    .::|||:
Yeast   578 IEEPRLKRFK-SSISSEISQTSTGNY--DSESAENSRSISFDG----KVSPPPI 624

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AMPKalpha	NP_477313.1	STKc_AMPK_alpha	25..280	CDD:270981	92/258 (36%)
		UBA_AID_AMPKalpha	297..360	CDD:270521	19/144 (13%)
		AMPKA_C	457..580	CDD:213378	23/96 (24%)
YPL150W	NP_015175.1	STKc_AMPK-like	40..286	CDD:270905	91/255 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910