Protein Alignment AMPKalpha and NPR1

DIOPT Version :9

• Sequence 1: NP_477313.1
• Gene: AMPKalpha / 43904
• FlyBaseID: FBgn0023169
• Length: 582
• Species: Drosophila melanogaster
• Sequence 2: NP_014216.1
• Gene: NPR1 / 855538
• SGDID: S000005127
• Length: 790
• Species: Saccharomyces cerevisiae
• Alignment Length: 392
• Identity: 100/392 - (25%)
• Similarity: 146/392 - (37%)
• Gaps: 112/392 - (28%)

  Fly    13 AAG--------SANGQPLVKIGH----------YL-LGATLGTGTFGKVK----IGEHQITRVK- 53
            |||        :.||..:....|          |: .||.||.|..|.||    |.:::|..||
Yeast   404 AAGNNSYSTSYNGNGDTIYSHSHGGSGIPFSKRYIKTGADLGAGAGGSVKLAQRISDNKIFAVKE 468

  Fly    54 VAVKILNRQKIKSLDVVGKIRREIQNLKLFRHPHIIKLYQVISTPSDIFMIMEYVSGGELFDYIV 118
            ...|..|..|   .|.|.||..|........||:||:..:::.....|..:|||.. .:|| .||
Yeast   469 FRTKFENESK---RDYVKKITSEYCIGTTLNHPNIIETIEIVYENDRILQVMEYCE-YDLF-AIV 528

  Fly   119 KHGKLQEHQARRFFQQIISGVDYCHRHMIVHRDLKPENLLLDHNMHVKIADFG--------LSNM 175
            ...|:...:....|:||::||.|.|...:.|||||.:|.:::....||:.|||        .|..
Yeast   529 MSNKMSYEEICCCFKQILTGVQYLHSIGLAHRDLKLDNCVINEKGIVKLIDFGAAVVFSYPFSKN 593

  Fly   176 MLDGEFLRTSCGSPNYAAPEVISGKLYAGPEVDIWSCGVILYALL-------------------- 220
            :::...:   .||..|.||||.....|....|||||..:|...::
Yeast   594 LVEASGI---VGSDPYLAPEVCIFAKYDPRPVDIWSSAIIFACMILKKFPWKIPKLRDNSFKLFC 655

  Fly   221 ----CGTL----------PFDDEHVPTLFRKIKSG-----------------IFPIPEYLNKQVV 254
                |.:|          |..||...|..:|.:|.                 :..:||    :..
Yeast   656 SGRDCDSLSSLVTRTPDPPSYDESHSTEKKKPESSSNNVSDPNNVNIGPQRLLHSLPE----ETQ 716

  Fly   255 NLVCQMLQVDPLKRANIEEIKKHEWFQKDLPAYLFPSSIEQDSNVIDTYAVAEVCTKFGVKETEV 319
            ::|.:|:.:.|..|.|||||.:..|.:.                 ||...:.|....|.|...|.
Yeast   717 HIVGRMIDLAPACRGNIEEIMEDPWIRS-----------------IDMCHLVEDGLSFKVVRGED 764

  Fly   320 HN 321
            |:
Yeast   765 HH 766

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AMPKalpha	NP_477313.1	STKc_AMPK_alpha	25..280	CDD:270981	87/329 (26%)
		UBA_AID_AMPKalpha	297..360	CDD:270521	7/25 (28%)
		AMPKA_C	457..580	CDD:213378
NPR1	NP_014216.1	PKc_like	451..742	CDD:419665	79/302 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157345343
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930