Protein Alignment AMPKalpha and PSK2

DIOPT Version :10

• Sequence 1: NP_477313.1
• Gene: AMPKalpha / 43904
• FlyBaseID: FBgn0023169
• Length: 582
• Species: Drosophila melanogaster
• Sequence 2: NP_014597.1
• Gene: PSK2 / 854111
• SGDID: S000005405
• Length: 1101
• Species: Saccharomyces cerevisiae
• Alignment Length: 301
• Identity: 86/301 - (28%)
• Similarity: 148/301 - (49%)
• Gaps: 40/301 - (13%)

  Fly     4 MRAAAAEAVAAGSANGQPLVKIGHYLLGATLGTGTFGKVKIGEHQITRVKVAVKILNRQKIKSLD 68
            ::|.......|...:.:.:.|...:.:...:|.|.:|||.:..|......|.:|::.:::| .:|
Yeast   817 LKATYLTTPEANIGSQKRIKKFSDFTILQVMGEGAYGKVNLCIHNREHYIVVIKMIFKERI-LVD 880

  Fly    69 V------VGKIRREIQ---NLKLFRHPHIIKL--------YQVISTPSDIFMIMEYVSGG----E 112
            .      :|.|..|||   .|......:|:||        |..|.||         |.|.    :
Yeast   881 TWVRDRKLGTIPSEIQIMATLNKNSQENILKLLDFFEDDDYYYIETP---------VHGETGSID 936

  Fly   113 LFDYIVKHGKLQEHQARRFFQQIISGVDYCHRHMIVHRDLKPENLLLDHNMHVKIADFGLSNMML 177
            |||.|.....:.||:|:..|:|:::.:.:.|...|||||:|.||:::|.:..||:.|||.:..:.
Yeast   937 LFDVIEFKKDMVEHEAKLVFKQVVASIKHLHDQGIVHRDIKDENVIVDSHGFVKLIDFGSAAYIK 1001

  Fly   178 DGEFLRTSCGSPNYAAPEVISGKLYAGPEVDIWSCGVILYALLCGTLPF--DDEHVPTLFRKIKS 240
            .|.| ....|:.:||||||:.|..|.|...|||:.||:||.::....|:  .||.:....|..||
Yeast  1002 SGPF-DVFVGTMDYAAPEVLGGSSYKGKPQDIWALGVLLYTIIYKENPYYNIDEILEGELRFDKS 1065

  Fly   241 GIFPIPEYLNKQVVNLVCQMLQVDPLKRANIEEIKKHEWFQ 281
                  |:::::.::|:.::|..:..||..|:||.:.:|.:
Yeast  1066 ------EHVSEECISLIKRILTREVDKRPTIDEIYEDKWLK 1100

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AMPKalpha	NP_477313.1	STKc_AMPK_alpha	25..280	CDD:270981	82/277 (30%)
		UBA_AID_AMPKalpha	297..360	CDD:270521
		AMPKA_C	457..580	CDD:213378
PSK2	NP_014597.1	STKc_PASK	840..1099	CDD:270906	82/275 (30%)