Protein Alignment AMPKalpha and PTK1

DIOPT Version :9

• Sequence 1: NP_477313.1
• Gene: AMPKalpha / 43904
• FlyBaseID: FBgn0023169
• Length: 582
• Species: Drosophila melanogaster
• Sequence 2: NP_012723.3
• Gene: PTK1 / 853635
• SGDID: S000001681
• Length: 662
• Species: Saccharomyces cerevisiae
• Alignment Length: 434
• Identity: 110/434 - (25%)
• Similarity: 160/434 - (36%)
• Gaps: 139/434 - (32%)

  Fly    81 KLFRHPHIIKLYQVISTPSDIF------MIMEYVSGGELFDYIVKHGKLQEHQARRF--FQQIIS 137
            :|..|.||...:.::..|:.::      .:|| :...:||..|.|.|......|.:|  |:|:..
Yeast   252 QLSHHVHITNTFLLVKVPTTVYTTRGWGFVME-LGLRDLFAMIQKSGWRSVALAEKFCIFKQVAC 315

  Fly   138 GVDYCHRHMIVHRDLKPENLLLDHNMHVKIADFGLSNMM-LDGEFLRT---SC----GSPNYAAP 194
            ||.:||...|.||||||||:||..:...|:.|||:|:.. .|...|.:   .|    |||.||.|
Yeast   316 GVKFCHDQGIAHRDLKPENVLLSPDGVCKLTDFGISDWYHTDPHDLSSPVKKCAGMIGSPPYAPP 380

  Fly   195 EVI--SGKLYAGPE---------VDIWSCGVILYALLCGTLPF-DDEHVPTLFR----------- 236
            ||:  ..|.:...|         :|.:..|:||..|:...:|| :.....|.||
Yeast   381 EVMFYDSKKHYDTELQQPYDPRALDCYGLGIILMTLVNNVIPFLESCSFDTGFRDYCDAYENFIR 445

  Fly   237 ------KIKSGIFPIP--------EYLNKQVVNLVCQMLQVDPLKRANIEEIKKHEWFQKDLPAY 287
                  :.:....|.|        .:.|.....:..::...:...|..|:::.:..|||
Yeast   446 LHDRAFRNRGNYRPGPGMEYHLARNFKNGHASRVAWRLADPEAATRYTIDDLFEDPWFQ------ 504

  Fly   288 LFPSSIEQDSNVIDTYAVAEVCTKFGVKETEVHNSLLSGDPHDQLAIAYHLIIDNKRFADDAANQ 352
                .||...:..|.|    ||.|..:|.|...|      |.     .:|:       |.|.|..
Yeast   505 ----GIETCVDANDKY----VCKKPIIKTTTYEN------PR-----GFHI-------ATDVAAT 543

  Fly   353 INEINNFF----------------------VAGSPPPPPP--------------PPVPQSSMDHQ 381
            ....|.|.                      :|.|||||||              .|.||
Yeast   544 TPTSNPFLKNRVPIRSMVDIAAHPSPTATVLASSPPPPPPATHVPAEALFTLRETPPPQ------ 602

  Fly   382 APLATVTVGGGTSASSGTATPVPPVAGGTPSSTIPIRPH-PERI 424
              |||:|:     :....|||.|. |...||:.  :|.| |.|:
Yeast   603 --LATLTL-----SEEPPATPAPS-APSAPSAR--VRGHSPHRV 636

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AMPKalpha	NP_477313.1	STKc_AMPK_alpha	25..280	CDD:270981	64/251 (25%)
		UBA_AID_AMPKalpha	297..360	CDD:270521	14/62 (23%)
		AMPKA_C	457..580	CDD:213378
PTK1	NP_012723.3	PKc_like	202..503	CDD:419665	64/251 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157345282
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24343
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.030