Protein Alignment AMPKalpha and HAL5

DIOPT Version :9

• Sequence 1: NP_477313.1
• Gene: AMPKalpha / 43904
• FlyBaseID: FBgn0023169
• Length: 582
• Species: Drosophila melanogaster
• Sequence 2: NP_012370.1
• Gene: HAL5 / 853274
• SGDID: S000003701
• Length: 855
• Species: Saccharomyces cerevisiae
• Alignment Length: 339
• Identity: 86/339 - (25%)
• Similarity: 134/339 - (39%)
• Gaps: 98/339 - (28%)

  Fly    34 LGTGTFGKVKIGEHQITRVKVAVKIL------NRQK----IKSLD-------------------- 68
            :|.|.:|.|||    ..|.|.|..:|      |.:|    :|.|.
Yeast   509 VGAGAYGVVKI----CARCKTAKDVLPYSTYSNGKKLFFAVKELKPKPGDQIDKFCTRLTSEFII 569

  Fly    69 --------------VVGKIRREIQNLKLFRHPHIIKLYQVISTPSDIFMIMEYVSGGELFDYI-- 117
                          :.|.:.|......:|..|:|:|:..::...:....:||:.:.|:|:..:
Yeast   570 GHSLSHPHFEANAMIAGNVSRTTPPKHVFNAPNILKILDLMEYSNSFVEVMEFCASGDLYSLLTR 634

  Fly   118 -----------------VKHGK---LQEHQARRFFQQIISGVDYCHRHMIVHRDLKPENLLLDHN 162
                             ||.|.   |...:|..|.:|:::||.|.|.|.|.|.||||||:|...|
Yeast   635 NNISNESNNGSSRLIQTVKEGSGSPLHPLEADCFMKQLLNGVQYMHDHGIAHCDLKPENILFQPN 699

  Fly   163 MHVKIADFGLSNMMLDG-----EFLRTSCGSPNYAAP-EVISGKLYAGPEVDIWSCGVILYALLC 221
            ..:||.|||.|::....     .|...:.||..|.|| |.|....|....||.||||::...::.
Yeast   700 GLLKICDFGTSSVFQTAWEKHVHFQSGAMGSEPYVAPEEFIRDAEYDPRLVDCWSCGIVYCTMVM 764

  Fly   222 G------TLPFDDEHVPTLFRKIK-SGIFPIPEYLNKQVVNLVCQM-----------LQVDPLKR 268
            |      .:|..|....:...:|| .|.|    ||.:::.::..::           .||||.||
Yeast   765 GQYLWKIAIPEKDSLFKSFLSEIKDDGQF----YLFEELRHVSSELNRLRKIALYRTFQVDPTKR 825

  Fly   269 ANIEEIKKHEWFQK 282
            ..||::.:..|.:|
Yeast   826 ITIEQLLQSSWMRK 839

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AMPKalpha	NP_477313.1	STKc_AMPK_alpha	25..280	CDD:270981	84/335 (25%)
		UBA_AID_AMPKalpha	297..360	CDD:270521
		AMPKA_C	457..580	CDD:213378
HAL5	NP_012370.1	PKc_like	509..837	CDD:419665	84/335 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157345338
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930