Protein Alignment AMPKalpha and VHS1

DIOPT Version :10

• Sequence 1: NP_477313.1
• Gene: AMPKalpha / 43904
• FlyBaseID: FBgn0023169
• Length: 582
• Species: Drosophila melanogaster
• Sequence 2: NP_010533.1
• Gene: VHS1 / 851834
• SGDID: S000002655
• Length: 461
• Species: Saccharomyces cerevisiae
• Alignment Length: 334
• Identity: 86/334 - (25%)
• Similarity: 142/334 - (42%)
• Gaps: 94/334 - (28%)

  Fly    24 KIGHYLLGATLGTGTFGKV--------------------------------KIGEHQITRVKVAV 56
            :|.:||:.:.:|.|.:|.|                                ||.::.:...|...
Yeast     8 RINNYLITSQIGEGAYGLVYRALDIRTDRQYAIKAVVQSYGVSKEADMGNDKIHKNSVKLQKKLA 72

  Fly    57 KILNRQK----IKSLDVVGKIRREIQN------------------LKLFRHPHIIKLYQVISTPS 99
            |:....|    :.|:|:     ..|:|                  |::..|.:|:.:::|:.:..
Yeast    73 KLFKESKNVVRVPSIDL-----ESIENMSEEDFKKLPHYKEISLHLRVHHHKNIVTIHEVLQSAV 132

  Fly   100 DIFMIMEYVSGGELFDYIV--KHGKLQEHQARRFFQQIISGVDYCHRHMIVHRDLKPENLLLDHN 162
            ..|::|:|.. .:||..||  :|........::.|.||.|.::|||.|.|.|.|:||||||||..
Yeast   133 CTFIVMDYYP-TDLFTSIVDNRHFVTNGLLVKKVFLQICSALNYCHEHGIYHCDIKPENLLLDTE 196

  Fly   163 MHVKIADFGLSNMMLDGEFLRTS-C-GSPNYAAPEVIS---------------GKLYAGPEVDIW 210
            .:|.:.|||||.   ...:::.: | ||..|..||.||               ||:......|:|
Yeast   197 DNVFLCDFGLST---TSTYIKPNVCIGSSYYMPPERISFDGRVSSSKSGGHKLGKVCPSCNGDLW 258

  Fly   211 SCGVILYALLCGTLPF-----DDEHVPTLFRK---IKSGIFPIPEYLNKQVVNLVCQMLQVDPLK 267
            |.|:||..|.|...|:     .:::....|.|   |...|.|    |:....:|:.::|||:|..
Yeast   259 SLGIILINLTCIRNPWLKADKTEDNTYYYFTKDPNILKQILP----LSDDFYSLLSKILQVNPKN 319

  Fly   268 RANIEEIKK 276
            |.:::|:.|
Yeast   320 RMSLQELMK 328

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AMPKalpha	NP_477313.1	STKc_AMPK_alpha	25..280	CDD:270981	86/333 (26%)
		UBA_AID_AMPKalpha	297..360	CDD:270521
		AMPKA_C	457..580	CDD:213378
VHS1	NP_010533.1	STKc_Pat1_like	11..330	CDD:270895	85/331 (26%)