DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AMPKalpha and SNRK2-8

DIOPT Version :9

Sequence 1:	NP_477313.1	Gene:	AMPKalpha / 43904	FlyBaseID:	FBgn0023169	Length:	582	Species:	Drosophila melanogaster
Sequence 2:	NP_001077839.1	Gene:	SNRK2-8 / 844164	AraportID:	AT1G78290	Length:	343	Species:	Arabidopsis thaliana

Alignment Length:	290	Identity:	118/290 - (40%)
Similarity:	166/290 - (57%)	Gaps:	16/290 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 YLLGATLGTGTFGKVKIGEHQITRVKVAVKILNR-QKIKSLDVVGKIRREIQNLKLFRHPHIIKL 91
            |.:...:|:|.||..|:...:.::...|||.:.| |||..     .::|||.|.:...||:||:.
plant     4 YEIVKDIGSGNFGVAKLVRDKFSKELFAVKFIERGQKIDE-----HVQREIMNHRSLIHPNIIRF 63

  Fly    92 YQVISTPSDIFMIMEYVSGGELFDYIVKHGKLQEHQARRFFQQIISGVDYCHRHMIVHRDLKPEN 156
            .:|:.|.:.:.::|||.:|||||..|...|:..|.:||.||||:||||:|||...|.|||||.||
plant    64 KEVLLTATHLALVMEYAAGGELFGRICSAGRFSEDEARFFFQQLISGVNYCHSLQICHRDLKLEN 128

  Fly   157 LLLDHN--MHVKIADFGLSNMMLDGEFLRTSCGSPNYAAPEVISGKLYAGPEVDIWSCGVILYAL 219
            .|||.:  ..|||.|||.|...:.....:|:.|:|.|.||||:|.|.|.|...|:|||||.||.:
plant   129 TLLDGSEAPRVKICDFGYSKSGVLHSQPKTTVGTPAYIAPEVLSTKEYDGKIADVWSCGVTLYVM 193

  Fly   220 LCGTLPFDDEHVPTLFRK----IKSGIFPIPEY--LNKQVVNLVCQMLQVDPLKRANIEEIKKHE 278
            |.|..||:|...|..|||    |....:.||:|  ::.:..:|:.::...:|.||..|||||.|.
plant   194 LVGAYPFEDPSDPKDFRKTIGRILKAQYAIPDYVRVSDECRHLLSRIFVANPEKRITIEEIKNHS 258

  Fly   279 WFQKDLPAYLFPSSIEQDSNVIDTYAVAEV 308
            ||.|:||..::..|:..  |...|..|.|:
plant   259 WFLKNLPVEMYEGSLMM--NGPSTQTVEEI 286

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AMPKalpha	NP_477313.1	STKc_AMPK_alpha	25..280	CDD:270981	108/260 (42%)
		UBA_AID_AMPKalpha	297..360	CDD:270521	4/12 (33%)
		AMPKA_C	457..580	CDD:213378
SNRK2-8	NP_001077839.1	STKc_SnRK2	3..259	CDD:271132	108/259 (42%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24343
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010