Protein Alignment AMPKalpha and TSSK1B

DIOPT Version :10

• Sequence 1: NP_477313.1
• Gene: AMPKalpha / 43904
• FlyBaseID: FBgn0023169
• Length: 582
• Species: Drosophila melanogaster
• Sequence 2: NP_114417.1
• Gene: TSSK1B / 83942
• HGNCID: 14968
• Length: 367
• Species: Homo sapiens
• Alignment Length: 263
• Identity: 103/263 - (39%)
• Similarity: 154/263 - (58%)
• Gaps: 10/263 - (3%)

  Fly    28 YLLGATLGTGTFGKVKIGEHQITRVKVAVKILNRQKIKSLDVVGK-IRREIQNLKLFRHPHIIKL 91
            ||||..||.|::.|||....:..:..||:||::|:|..: |.:.| :.|||:.|.:..|..|||.
Human    12 YLLGINLGEGSYAKVKSAYSERLKFNVAIKIIDRKKAPA-DFLEKFLPREIEILAMLNHCSIIKT 75

  Fly    92 YQVISTP-SDIFMIMEYVSGGELFDYIVKHGKLQEHQARRFFQQIISGVDYCHRHMIVHRDLKPE 155
            |::..|. ..::::||....|:|.:.|...|.|.|.:||:.|.|:...:.|||...:||||||.:
Human    76 YEIFETSHGKVYIVMELAVQGDLLELIKTRGALHEDEARKKFHQLSLAIKYCHDLDVVHRDLKCD 140

  Fly   156 NLLLDHNMHVKIADFGLSNMMLDGE-----FLRTSCGSPNYAAPEVISGKLYAGPEVDIWSCGVI 215
            |||||.:.::|::||..|...|..:     ..:|.||||.||||||:.|..|.....||||.|||
Human   141 NLLLDKDFNIKLSDFSFSKRCLRDDSGRMALSKTFCGSPAYAAPEVLQGIPYQPKVYDIWSLGVI 205

  Fly   216 LYALLCGTLPFDDEHVPTLFR--KIKSGIFPIPEYLNKQVVNLVCQMLQVDPLKRANIEEIKKHE 278
            ||.::||::|:||.::..:.|  |.....||..::|..:..:|:..|||.|..:|.:|:||..|.
Human   206 LYIMVCGSMPYDDSNIKKMLRIQKEHRVNFPRSKHLTGECKDLIYHMLQPDVNRRLHIDEILSHC 270

  Fly   279 WFQ 281
            |.|
Human   271 WMQ 273

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AMPKalpha	NP_477313.1	STKc_AMPK_alpha	25..280	CDD:270981	101/260 (39%)
		UBA_AID_AMPKalpha	297..360	CDD:270521
		AMPKA_C	457..580	CDD:213378
TSSK1B	NP_114417.1	STKc_TSSK1_2-like	10..272	CDD:271067	101/260 (39%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	276..367