DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AMPKalpha and SNRK2.4

DIOPT Version :9

Sequence 1:	NP_477313.1	Gene:	AMPKalpha / 43904	FlyBaseID:	FBgn0023169	Length:	582	Species:	Drosophila melanogaster
Sequence 2:	NP_001031021.2	Gene:	SNRK2.4 / 837637	AraportID:	AT1G10940	Length:	371	Species:	Arabidopsis thaliana

Alignment Length:	359	Identity:	127/359 - (35%)
Similarity:	179/359 - (49%)	Gaps:	67/359 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 YLLGATLGTGTFGKVKIGEHQITRVKVAVKILNR-QKIKSLDVVGKIRREIQNLKLFRHPHIIKL 91
            |.|...:|.|.||..::.:.:.::..||:|.:.| .||..     .:.|||.|.:..|||:||:.
plant     4 YELVKDIGAGNFGVARLMKVKNSKELVAMKYIERGPKIDE-----NVAREIINHRSLRHPNIIRF 63

  Fly    92 YQVISTPSDIFMIMEYVSGGELFDYIVKHGKLQEHQ--------ARRFFQQIISGVDYCHRHMIV 148
            .:|:.||:.:.:.|||.:|||||:.|...|:..|.:        ||.||||:||||.|||...|.
plant    64 KEVVLTPTHLAIAMEYAAGGELFERICSAGRFSEDEEEGNKRKHARYFFQQLISGVSYCHAMQIC 128

  Fly   149 HRDLKPENLLLDHN--MHVKIADFGLSNMMLDGEFLRTSCGSPNYAAPEVISGKLYAGPEVDIWS 211
            |||||.||.|||.:  ..:||.|||.|...|.....:::.|:|.|.||||:|.:.|.|...|:||
plant   129 HRDLKLENTLLDGSPAPRLKICDFGYSKSSLLHSRPKSTVGTPAYIAPEVLSRREYDGKMADVWS 193

  Fly   212 CGVILYALLCGTLPFDDEHVPTLFR----KIKSGIFPIPEY--LNKQVVNLVCQMLQVDPLKRAN 270
            |||.||.:|.|..||:|:..|..||    ||.:..:.||:|  :::...||:.::...:.|||..
plant   194 CGVTLYVMLVGAYPFEDQEDPKNFRKTIQKIMAVQYKIPDYVHISQDCKNLLSRIFVANSLKRIT 258

  Fly   271 IEEIKKHEWFQKDLPAYLFPSSIEQDSNVIDTYAVAEVCTKFGVKETEVHNSLLSGDPHDQLAIA 335
            |.|||||.||.|:||..|                            ||.             |.|
plant   259 IAEIKKHSWFLKNLPREL----------------------------TET-------------AQA 282

  Fly   336 YHLIIDNKRFADDAANQINEINNFFVAGSPPPPP 369
            .:...:|..|:.....:|.:|    ||.:..|||
plant   283 AYFKKENPTFSLQTVEEIMKI----VADAKTPPP 312

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AMPKalpha	NP_477313.1	STKc_AMPK_alpha	25..280	CDD:270981	108/268 (40%)
		UBA_AID_AMPKalpha	297..360	CDD:270521	8/62 (13%)
		AMPKA_C	457..580	CDD:213378
SNRK2.4	NP_001031021.2	STKc_SnRK2	3..267	CDD:271132	108/267 (40%)
SNRK2.4	NP_001031021.2	S_TKc	4..268	CDD:214567	108/268 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24343
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010