DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AMPKalpha and SNRK2.5

DIOPT Version :9

Sequence 1:	NP_477313.1	Gene:	AMPKalpha / 43904	FlyBaseID:	FBgn0023169	Length:	582	Species:	Drosophila melanogaster
Sequence 2:	NP_201170.1	Gene:	SNRK2.5 / 836485	AraportID:	AT5G63650	Length:	360	Species:	Arabidopsis thaliana

Alignment Length:	264	Identity:	113/264 - (42%)
Similarity:	160/264 - (60%)	Gaps:	14/264 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 LGTGTFGKVKIGEHQITRVKVAVKILNR-QKIKSLDVVGKIRREIQNLKLFRHPHIIKLYQVIST 97
            ||.|.||..::..|:.|:..||:|.:.| :||..     .:.|||.|.:..|||:||:..:||.|
plant    10 LGAGNFGVARLLRHKETKELVAMKYIERGRKIDE-----NVAREIINHRSLRHPNIIRFKEVILT 69

  Fly    98 PSDIFMIMEYVSGGELFDYIVKHGKLQEHQARRFFQQIISGVDYCHRHMIVHRDLKPENLLLDHN 162
            |:.:.::|||.||||||:.|...|:..|.:||.||||:|.||||||...|.|||||.||.|||.:
plant    70 PTHLAIVMEYASGGELFERICNAGRFSEAEARYFFQQLICGVDYCHSLQICHRDLKLENTLLDGS 134

  Fly   163 MH--VKIADFGLSNMMLDGEFLRTSCGSPNYAAPEVISGKLYAGPEVDIWSCGVILYALLCGTLP 225
            ..  :||.|||.|...|.....:::.|:|.|.||||:|.:.|.|...|:|||||.||.:|.|..|
plant   135 PAPLLKICDFGYSKSSLLHSRPKSTVGTPAYIAPEVLSRREYDGKHADVWSCGVTLYVMLVGGYP 199

  Fly   226 FDDEHVPTLFRK----IKSGIFPIPEY--LNKQVVNLVCQMLQVDPLKRANIEEIKKHEWFQKDL 284
            |:|...|..|||    |.:..:.||:|  ::::..:|:.::...:..||..::|||||.|:.|:|
plant   200 FEDPDDPRNFRKTIQRIMAVQYKIPDYVHISQECRHLLSRIFVTNSAKRITLKEIKKHPWYLKNL 264

  Fly   285 PAYL 288
            |..|
plant   265 PKEL 268

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AMPKalpha	NP_477313.1	STKc_AMPK_alpha	25..280	CDD:270981	108/254 (43%)
		UBA_AID_AMPKalpha	297..360	CDD:270521
		AMPKA_C	457..580	CDD:213378
SNRK2.5	NP_201170.1	STKc_SnRK2	3..259	CDD:271132	108/253 (43%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24343
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010