DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment AMPKalpha and SNRK2.1

DIOPT Version :9

Sequence 1:	NP_477313.1	Gene:	AMPKalpha / 43904	FlyBaseID:	FBgn0023169	Length:	582	Species:	Drosophila melanogaster
Sequence 2:	NP_196476.1	Gene:	SNRK2.1 / 830760	AraportID:	AT5G08590	Length:	353	Species:	Arabidopsis thaliana

Alignment Length:	268	Identity:	112/268 - (41%)
Similarity:	162/268 - (60%)	Gaps:	14/268 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 LGTGTFGKVKIGEHQITRVKVAVKILNR-QKIKSLDVVGKIRREIQNLKLFRHPHIIKLYQVIST 97
            ||.|.||..::..|:.|:..||:|.:.| :||..     .:.|||.|.:..:||:||:..:||.|
plant    10 LGAGNFGVARLLRHKDTKELVAMKYIERGRKIDE-----NVAREIINHRSLKHPNIIRFKEVILT 69

  Fly    98 PSDIFMIMEYVSGGELFDYIVKHGKLQEHQARRFFQQIISGVDYCHRHMIVHRDLKPENLLLDHN 162
            |:.:.::|||.|||||||.|...|:..|.:||.||||:|.||||||...|.|||||.||.|||.:
plant    70 PTHLAIVMEYASGGELFDRICTAGRFSEAEARYFFQQLICGVDYCHSLQICHRDLKLENTLLDGS 134

  Fly   163 MH--VKIADFGLSNMMLDGEFLRTSCGSPNYAAPEVISGKLYAGPEVDIWSCGVILYALLCGTLP 225
            ..  :||.|||.|...:.....:::.|:|.|.||||:|.:.|.|...|:|||||.||.:|.|..|
plant   135 PAPLLKICDFGYSKSSILHSRPKSTVGTPAYIAPEVLSRREYDGKHADVWSCGVTLYVMLVGAYP 199

  Fly   226 FDDEHVPTLFRK----IKSGIFPIPEY--LNKQVVNLVCQMLQVDPLKRANIEEIKKHEWFQKDL 284
            |:|.:.|..|||    |.:..:.||:|  ::::..:|:.::...:..||..::|||.|.|:.|:|
plant   200 FEDPNDPKNFRKTIQRIMAVQYKIPDYVHISQECKHLLSRIFVTNSAKRITLKEIKNHPWYLKNL 264

  Fly   285 PAYLFPSS 292
            |..|..|:
plant   265 PKELLESA 272

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AMPKalpha	NP_477313.1	STKc_AMPK_alpha	25..280	CDD:270981	106/254 (42%)
		UBA_AID_AMPKalpha	297..360	CDD:270521
		AMPKA_C	457..580	CDD:213378
SNRK2.1	NP_196476.1	STKc_SnRK2	3..259	CDD:271132	106/253 (42%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24343
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010