Protein Alignment AMPKalpha and CIPK8

DIOPT Version :10

• Sequence 1: NP_477313.1
• Gene: AMPKalpha / 43904
• FlyBaseID: FBgn0023169
• Length: 582
• Species: Drosophila melanogaster
• Sequence 2: NP_194171.1
• Gene: CIPK8 / 828542
• AraportID: AT4G24400
• Length: 445
• Species: Arabidopsis thaliana
• Alignment Length: 554
• Identity: 183/554 - (33%)
• Similarity: 262/554 - (47%)
• Gaps: 149/554 - (26%)

  Fly    24 KIGHYLLGATLGTGTFGKVKIGEHQITRVKVAVKILNRQKIKSLDVVGKIRREIQNLKLFRHPHI 88
            |:|.|.||.|:|.|||.|||..::..|...||:||::|..|....:|.:|:|||..:||.|||.:
plant     5 KVGKYELGRTIGEGTFAKVKFAQNTETGESVAMKIVDRSTIIKRKMVDQIKREISIMKLVRHPCV 69

  Fly    89 IKLYQVISTPSDIFMIMEYVSGGELFDYIVKHGKLQEHQARRFFQQIISGVDYCHRHMIVHRDLK 153
            ::||:|:::.:.|::|:||::||||||.||::|:|.|.:||::|.|:|.||||||...:.|||||
plant    70 VRLYEVLASRTKIYIILEYITGGELFDKIVRNGRLSESEARKYFHQLIDGVDYCHSKGVYHRDLK 134

  Fly   154 PENLLLDHNMHVKIADFGLSNMMLDG-EFLRTSCGSPNYAAPEVISGKLYAGPEVDIWSCGVILY 217
            |||||||...::||:|||||.:...| ..|:|:||:|||.||||:|.|.|.|...||||||||||
plant   135 PENLLLDSQGNLKISDFGLSALPEQGVTILKTTCGTPNYVAPEVLSHKGYNGAVADIWSCGVILY 199

  Fly   218 ALLCGTLPFDDEHVPTLFRKIKSGIFPIPEYLNKQVVNLVCQMLQVDPLKRANIEEIKKHEWFQK 282
            .|:.|.||||:..:|||:.||....|..|.|......:|:.::|..:|..|..|.||:|.|||.|
plant   200 VLMAGYLPFDEMDLPTLYSKIDKAEFSCPSYFALGAKSLINRILDPNPETRITIAEIRKDEWFLK 264

  Fly   283 D-LPAYLFPSSIEQDSNVIDTYAVAEVCTKFGVKETEVHNSLLSGDPHDQ------------LAI 334
            | .|..|..   .:..|:.|.||..:                   ||.:|            |.:
plant   265 DYTPVQLID---YEHVNLDDVYAAFD-------------------DPEEQTYAQDGTRDTGPLTL 307

  Fly   335 -AYHLIIDNK---------RFADDAANQINEINNFFVAGSPPPPPPPPVPQSSMDHQAPLATVTV 389
             |:.|||.::         |..|...:|...|::          .|..|..|||:
plant   308 NAFDLIILSQGLNLATLFDRGKDSMKHQTRFISH----------KPANVVLSSME---------- 352

  Fly   390 GGGTSASSGTATPVPPVAGGTPSSTIPIRPHPERIAPMRDRQLAMSVQTSGGGAFPEKTARGGTP 454
              ..|.|.|..|.:                          |...|.|:    |....||:
plant   353 --VVSQSMGFKTHI--------------------------RNYKMRVE----GLSANKTS----- 380

  Fly   455 IKRAKWHLGIRSQSKPNDIMLEVYRAMKALSYEWKIINPYHVRVRRQNVKTGKFSKMSLQLYQVD 519
                  |.         .::|||::           :.|..:.|..||...             |
plant   381 ------HF---------SVILEVFK-----------VAPSILMVDIQNAAG-------------D 406

  Fly   520 AKSYLLDFKSLTNDEVEQGDDVIMESLTPPPLSV 553
            |:.||..:|:..:    :.||:|.:   ||..|:
plant   407 AEEYLKFYKTFCS----KLDDIIWK---PPDASM 433

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AMPKalpha	NP_477313.1	STKc_AMPK_alpha	25..280	CDD:270981	126/255 (49%)
		UBA_AID_AMPKalpha	297..360	CDD:270521	16/84 (19%)
		AMPKA_C	457..580	CDD:213378	19/97 (20%)
CIPK8	NP_194171.1	Protein Kinases, catalytic domain	8..261	CDD:473864	124/252 (49%)
		CIPK_C	308..423	CDD:213380	36/214 (17%)