Protein Alignment AMPKalpha and KIN10

DIOPT Version :9

• Sequence 1: NP_477313.1
• Gene: AMPKalpha / 43904
• FlyBaseID: FBgn0023169
• Length: 582
• Species: Drosophila melanogaster
• Sequence 2: NP_850488.1
• Gene: KIN10 / 821259
• AraportID: AT3G01090
• Length: 535
• Species: Arabidopsis thaliana
• Alignment Length: 600
• Identity: 254/600 - (42%)
• Similarity: 335/600 - (55%)
• Gaps: 131/600 - (21%)

  Fly    15 GSANGQPLVKIGHYLLGATLGTGTFGKVKIGEHQITRVKVAVKILNRQKIKSLDVVGKIRREIQN 79
            ||.:|...: :.:|.||.|||.|:||:|||.||.:|..|||:|||||:|||::::..|:||||:.
plant    30 GSRSGVESI-LPNYKLGRTLGIGSFGRVKIAEHALTGHKVAIKILNRRKIKNMEMEEKVRREIKI 93

  Fly    80 LKLFRHPHIIKLYQVISTPSDIFMIMEYVSGGELFDYIVKHGKLQEHQARRFFQQIISGVDYCHR 144
            |:||.|||||:||:||.||:||:::||||:.||||||||:.|:|||.:||.|||||||||:||||
plant    94 LRLFMHPHIIRLYEVIETPTDIYLVMEYVNSGELFDYIVEKGRLQEDEARNFFQQIISGVEYCHR 158

  Fly   145 HMIVHRDLKPENLLLDHNMHVKIADFGLSNMMLDGEFLRTSCGSPNYAAPEVISGKLYAGPEVDI 209
            :|:|||||||||||||...:||||||||||:|.||.||:|||||||||||||||||||||||||:
plant   159 NMVVHRDLKPENLLLDSKCNVKIADFGLSNIMRDGHFLKTSCGSPNYAAPEVISGKLYAGPEVDV 223

  Fly   210 WSCGVILYALLCGTLPFDDEHVPTLFRKIKSGIFPIPEYLNKQVVNLVCQMLQVDPLKRANIEEI 274
            ||||||||||||||||||||::|.||:|||.||:.:|.:|:....:|:.:||.|||:||..|.||
plant   224 WSCGVILYALLCGTLPFDDENIPNLFKKIKGGIYTLPSHLSPGARDLIPRMLVVDPMKRVTIPEI 288

  Fly   275 KKHEWFQKDLPAYLF--PSSIEQDSNVIDTYAVAEVCTKFGVKETEVHNSLLSGDPHDQLAIAYH 337
            ::|.|||..||.||.  |....|.:..||...:.|| ...|.....:..||.:...:|. .:.|:
plant   289 RQHPWFQAHLPRYLAVPPPDTVQQAKKIDEEILQEV-INMGFDRNHLIESLRNRTQNDG-TVTYY 351

  Fly   338 LIIDNKRFADDAANQINEINNFFVAGSPPPPPPPPVPQSSMDHQAPLATVTVGGGTSASSG-TAT 401
            ||:|| ||                                                .|||| ...
plant   352 LILDN-RF------------------------------------------------RASSGYLGA 367

  Fly   402 PVPPVAGGTPSSTIPIRPHP-ERIAPMRDRQLAMSVQTSGGGAFPEKTARGGTPIKRAKWHLGIR 465
            .......|||      |.|| |.:|.....:|...::..|.|      .|...|::| ||.||::
plant   368 EFQETMEGTP------RMHPAESVASPVSHRLPGLMEYQGVG------LRSQYPVER-KWALGLQ 419

  Fly   466 SQSKPNDIMLEVYRAMKALSYEWKIINPYHVRVR------------------------------R 500
            |::.|.:||.||.:|::.|:..||.|..|:::.|                              .
plant   420 SRAHPREIMTEVLKALQDLNVCWKKIGHYNMKCRWVPNSSADGMLSNSMHDNNYFGDESSIIENE 484

  Fly   501 QNVKTGKFSKMSLQLYQVDAKSYLLDFKSLTNDEVEQGDDVIMESLTPPPLSVSGVMPLQPTGHH 565
            ..||:....|..:|||:.....||||.:.:      ||...:
plant   485 AAVKSPNVVKFEIQLYKTRDDKYLLDLQRV------QGPQFL----------------------- 520

  Fly   566 TMEFFEMCAALIIQL 580
               |.::|||.:.||
plant   521 ---FLDLCAAFLAQL 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AMPKalpha	NP_477313.1	STKc_AMPK_alpha	25..280	CDD:270981	174/254 (69%)
		UBA_AID_AMPKalpha	297..360	CDD:270521	15/62 (24%)
		AMPKA_C	457..580	CDD:213378	34/152 (22%)
KIN10	NP_850488.1	STKc_AMPK_alpha	39..294	CDD:270981	174/254 (69%)
		S_TKc	42..294	CDD:214567	174/251 (69%)
		UBA_SnRK1_plant	316..356	CDD:270520	11/41 (27%)
		AMPKA_C	411..532	CDD:213378	34/153 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	376	1.000	Domainoid score	I169
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	418	1.000	Inparanoid score	I441
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000976
OrthoInspector	1	1.000	-	-		otm3018
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24343
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X997
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	9	9.020