Protein Alignment AMPKalpha and trib1

DIOPT Version :10

• Sequence 1: NP_477313.1
• Gene: AMPKalpha / 43904
• FlyBaseID: FBgn0023169
• Length: 582
• Species: Drosophila melanogaster
• Sequence 2: XP_009292604.1
• Gene: trib1 / 792957
• ZFINID: ZDB-GENE-091207-4
• Length: 349
• Species: Danio rerio
• Alignment Length: 328
• Identity: 86/328 - (26%)
• Similarity: 154/328 - (46%)
• Gaps: 57/328 - (17%)

  Fly     2 PQMRAAAAEAVAAGSANGQPLVKIGHYLLGATLGTGTF--GKVKIGEHQITRVKVAVKILNRQKI 64
            |::..::|:|...||:.|.|       :.||.|...:.  |..:||:.      :.|.:.:|..:
Zfish    31 PRLSESSADAGLLGSSPGSP-------VSGAPLSVTSAHQGPARIGQF------LLVPLTDRPGV 82

  Fly    65 KS---LDVVGKIRREIQNLKLFRHPHIIKLYQVISTPSDIFMIMEYVSG------------GELF 114
            :|   :|...::..::.::..::..  |:.|.::|...:|..|.:.|.|            |::.
Zfish    83 QSALDMDTGEELLCKVFDMGQYQEK--IRAYSMLSNHKNIAQIKDIVLGESKAYVFQEKDFGDMH 145

  Fly   115 DYIVKHGKLQEHQARRFFQQIISGVDYCHRHMIVHRDLKPENLLL--DHNMHVKIADFGLSNMML 177
            .::....:|.|..|.:.|.|::|.|::||:..||..|||....:.  :...|:|:.  ||
Zfish   146 TFVKSSKRLSEDLASKLFYQVVSAVNHCHQVGIVLGDLKLRKFVFTDEKRTHLKLE--GL----- 203

  Fly   178 DGEFLRTSCGS----------PNYAAPEVIS-GKLYAGPEVDIWSCGVILYALLCGTLPFDDEHV 231
              |:....||.          |.|.:||::: |..|:|.:.|:||.||:||.:|.|..||.|...
Zfish   204 --EYCHVLCGEDDSMFDTHGCPAYVSPEILNGGGCYSGKQADVWSLGVMLYTMLVGRYPFHDADP 266

  Fly   232 PTLFRKIKSGIFPIPEYLNKQVVNLVCQMLQVDPLKRANIEEIKKHEWFQKDLPAYLFPSSIEQD 296
            .|||.||:.|.:.:|:.|:.....|:..:|:.||.:|....|:..|.||..::.....|   ||:
Zfish   267 ATLFSKIRRGTYCLPDGLSLTARCLLRSLLRKDPGERLTAAEVLIHPWFNSNIQDSRNP---EQE 328

  Fly   297 SNV 299
            .|:
Zfish   329 VNL 331

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AMPKalpha	NP_477313.1	STKc_AMPK_alpha	25..280	CDD:270981	73/284 (26%)
		UBA_AID_AMPKalpha	297..360	CDD:270521	1/3 (33%)
		AMPKA_C	457..580	CDD:213378
trib1	XP_009292604.1	Protein Kinases, catalytic domain	74..315	CDD:473864	67/251 (27%)