Protein Alignment AMPKalpha and RGD1560718

DIOPT Version :9

• Sequence 1: NP_477313.1
• Gene: AMPKalpha / 43904
• FlyBaseID: FBgn0023169
• Length: 582
• Species: Drosophila melanogaster
• Sequence 2: XP_038957446.1
• Gene: RGD1560718 / 499027
• RGDID: 1560718
• Length: 501
• Species: Rattus norvegicus
• Alignment Length: 543
• Identity: 151/543 - (27%)
• Similarity: 246/543 - (45%)
• Gaps: 82/543 - (15%)

  Fly    28 YLLGATLGTGTFGKVKIGEHQITRVKVAVKILNRQKIKSLDVVGKIRREIQNLKLFRHPHIIKLY 92
            ||:..|:|.|....||:..|::|...||||:|    :|......::..|::.:....||:|:.|.
  Rat    27 YLVLNTIGHGFHAAVKLAVHRLTGTPVAVKML----LKRQQWCQQVTSEVEIMMRINHPNIVSLI 87

  Fly    93 QVISTPSDIFMIMEYVSGGELFDYIVKHGKLQEHQARRFFQQIISGVDYCHRHMIVHRDLKPENL 157
            |||.|....::|||...|.:|:..|.:.|.|||.:||..|:|::|.|.|||:..|:||||||:|:
  Rat    88 QVIDTEKITYLIMELAKGNQLYSRIKEAGHLQEDEARGIFRQLLSAVGYCHKEGIIHRDLKPDNI 152

  Fly   158 LLDHNMHVKIADFGLSNMMLDGEFLRTSCGSPNYAAPEVISGKLYAGPEVDIWSCGVILYALLCG 222
            |:|....:||.|||.:..:..|:.|||..|:..::|||:..||.|.||:||:|:.|||||.:..|
  Rat   153 LVDTKGRIKIVDFGSATQVRPGQKLRTHYGTYAFSAPELFLGKFYEGPKVDVWALGVILYYMTVG 217

  Fly   223 TLPFDDEHVPTLFRKIKSGIFPIPEYLNKQVVNLVCQMLQVDPLKRANIEEIKKHEWFQKDLPAY 287
            .|||:...:|.|.|::..|.:..|..|::::.:|:..:::|:..:|..|.::..|.|.:.|...
  Rat   218 KLPFEAVRLPLLRRQVVLGTYAEPLGLSEELQDLLSLLMKVNSQQRPTIPDLLTHPWLKIDSEG- 281

  Fly   288 LFPSSIEQDSNVIDTYAVAEVCTKFGVKETEVHNSLLSGDPHDQLAIAYHLIIDNKRFADDAANQ 352
             ||...::...:....|:.......|.:..||.:||.....:..:|..|        |.:..|.|
  Rat   282 -FPQPCKELIPLRPDPAILRAMQDIGFEAQEVKDSLDQKKFNQSMACYY--------FLEKQALQ 337

  Fly   353 INEINNFFVAGSPPPPPPPPVPQSSMDHQAPLATVTVGGGTSASSGTATPVPPVAGGTPSSTIPI 417
            ..:|        |..|.|...|..::|:.|    .:|.|.....|
  Rat   338 ECDI--------PTRPHPCMTPFPTLDYPA----TSVRGLRRRGS-------------------- 370

  Fly   418 RPHPERIAPMRDRQLAMSVQTSGGGAFPEKTARGGTPIKRAKWHLGIRSQSKPNDIMLEVYRAMK 482
              .|..:....|.|.:...||:..|.           :|||.|..|:  ..:|:.|...|
  Rat   371 --EPRWLGSSSDSQGSDLGQTASHGL-----------VKRASWPGGL--LCRPHQITPTV----- 415

  Fly   483 ALSYEWKIINPYHVRVRRQNVK------TGKFSKMSLQLYQVDAKSYLLDFKSLTNDEVEQGDDV 541
            .|::...|.:|....|..:..|      |...|..|.::..|.::.:...|:....: :..|
  Rat   416 ELTHRISISDPCFYSVHSKGKKTINTKSTEDKSSASAEVKPVASRPWPKRFRGWVKN-IRNG--- 476

  Fly   542 IME------SLTPPPLSVSGVMP 558
            :|.      |...|||..:.|:|
  Rat   477 LMNLCCCIPSRKKPPLGHNRVVP 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AMPKalpha	NP_477313.1	STKc_AMPK_alpha	25..280	CDD:270981	94/251 (37%)
		UBA_AID_AMPKalpha	297..360	CDD:270521	12/62 (19%)
		AMPKA_C	457..580	CDD:213378	25/114 (22%)
RGD1560718	XP_038957446.1	STKc_AMPK-like	26..274	CDD:270905	94/250 (38%)
		UBA_MARK_Par1	294..333	CDD:270522	9/46 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24343
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010