Protein Alignment AMPKalpha and CG1227

DIOPT Version :10

• Sequence 1: NP_477313.1
• Gene: AMPKalpha / 43904
• FlyBaseID: FBgn0023169
• Length: 582
• Species: Drosophila melanogaster
• Sequence 2: NP_649712.1
• Gene: CG1227 / 40872
• FlyBaseID: FBgn0037491
• Length: 320
• Species: Drosophila melanogaster
• Alignment Length: 289
• Identity: 81/289 - (28%)
• Similarity: 131/289 - (45%)
• Gaps: 37/289 - (12%)

  Fly    28 YLLGATLGTGTFGKVKIGEHQITRVKVAVKILNRQKIKSLDVVGKIRREIQNLKLFRHPHIIKL- 91
            |.:...|.||.|..:.:||:..||...|:|   |....|:|......|||:|.:.....::|::
  Fly    30 YTIRERLATGGFSLIDLGENASTRRSYAIK---RITCHSIDDQNIALREIENCRKIDSENVIRVV 91

  Fly    92 -YQ-------VISTPSDIFMIMEYVSGGELFDYIVKHGKLQEH----QARRFFQQIISGVDYCHR 144
             |:       ||:|.|.:|:::.|...|.|.|::....:.|:|    |..:.|..:..|:...|.
  Fly    92 DYELKGQADIVINTTSTLFIVLPYYKHGSLADHLQLRSRKQDHMPEAQILQIFLGVCEGLKAIHE 156

  Fly   145 HM---IVHRDLKPENLLLDHNMHVKIADFG-LSNMML------DGEFLRTSC---GSPNYAAPEV 196
            .|   :.|||||..|:.|..:....|.|.| ::...|      |.:.|:...   .|..|.|||:
  Fly   157 AMPVPLAHRDLKTANICLSDSFEPIIVDLGSMTEARLQIVGQTDAQRLQDEAEERSSIVYRAPEL 221

  Fly   197 ISGKLYA--GPEVDIWSCGVILYALLCGTLPFDD--EHVPTLFRKIKSGIFPIPE--YLNKQVVN 255
            .:.|.|.  ....||||.|.:|||:.....|:|.  |...::...:.||...|||  ...:.:..
  Fly   222 FTVKTYCTIDERTDIWSLGCVLYAMCYFNSPYDPIYERGDSVALAVLSGNINIPEDSIYTEDMHE 286

  Fly   256 LVCQMLQVDPLKRANIEEI--KKHEWFQK 282
            |:..||:.||::|..:..:  :.|:..||
  Fly   287 LIKYMLRTDPMERPFVFSVIERTHDLIQK 315

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AMPKalpha	NP_477313.1	STKc_AMPK_alpha	25..280	CDD:270981	79/285 (28%)
		UBA_AID_AMPKalpha	297..360	CDD:270521
		AMPKA_C	457..580	CDD:213378
CG1227	NP_649712.1	STKc_16	29..314	CDD:270888	79/286 (28%)