Protein Alignment AMPKalpha and sff

DIOPT Version :9

• Sequence 1: NP_477313.1
• Gene: AMPKalpha / 43904
• FlyBaseID: FBgn0023169
• Length: 582
• Species: Drosophila melanogaster
• Sequence 2: NP_648814.3
• Gene: sff / 39732
• FlyBaseID: FBgn0036544
• Length: 861
• Species: Drosophila melanogaster
• Alignment Length: 594
• Identity: 194/594 - (32%)
• Similarity: 288/594 - (48%)
• Gaps: 118/594 - (19%)

  Fly    25 IGHYLLGATLGTGTFGKVKIGEHQITRVKVAVKILNRQKIKSLDVVGKIRREIQNLKLFRHPHII 89
            :|.|.|..|||.|..|.||:|.|.:...|||:||:||:|: |..|:.|:.|||..:||..|||::
  Fly    15 VGPYRLEKTLGKGQTGLVKLGVHCVIGKKVAIKIINREKL-SESVLMKVEREIAIMKLIDHPHVL 78

  Fly    90 KLYQVISTPSDIFMIMEYVSGGELFDYIVKHGKLQEHQARRFFQQIISGVDYCHRHMIVHRDLKP 154
            .|..|......:::|:|:|||||||||:||.|:|...:||:||:||||.:|:||.|.|.||||||
  Fly    79 GLSDVYENKKYLYLILEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLKP 143

  Fly   155 ENLLLDHNMHVKIADFGLSNMMLDGEFLRTSCGSPNYAAPEVISGKLYAGPEVDIWSCGVILYAL 219
            ||||||...::||||||::::...|..|.||||||:||.||||.|:.|.|.:.|:||||||||||
  Fly   144 ENLLLDEKNNIKIADFGMASLQPAGSMLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILYAL 208

  Fly   220 LCGTLPFDDEHVPTLFRKIKSGIFPIPEYLNKQVVNLVCQMLQVDPLKRANIEEIKKHEW----- 279
            |.|.|||||:::..|..|:|.|:|.||.::.....:|:..|::|:|.:|..:.||.:|.|
  Fly   209 LVGALPFDDDNLRQLLEKVKRGVFHIPHFVPPDCQSLLRGMIEVNPDRRLTLAEINRHPWVTAGG 273

  Fly   280 ---FQKDLP------AYLFPSSIEQDSNVIDTYAVAEVCTKFGVKETEVHNSLLSGDPHDQLAIA 335
               .:.:||      .::.|::...|.:|::.     :|:....||.|.....|....|:...:.
  Fly   274 KGELELELPMMEVVQTHVIPTATAVDPDVLNA-----ICSLGCFKEKEKLIQELLSSSHNTEKVI 333

  Fly   336 YHLIIDNKR----FADD---AANQINEINNFFVAGSPPPPPPPPVPQSSMDHQAPLATVTVGGGT 393
            |.|:::.||    ..||   |....:|::    |..||              :..|.|..:.|..
  Fly   334 YFLLLERKRRRPALEDDDEIAQKSRSELD----AVDPP--------------RKRLDTCRINGTN 380

  Fly   394 SASSGTATPVPPVAGGTP----------SSTIPIRPHPERIAPMRDRQLAMSVQTSGGGAFPEKT 448
            :.|.|..:...|:   ||          |||   |.|..|         :.:..||.
  Fly   381 APSYGQISEGSPL---TPRRQAFNFRSYSST---RNHQRR---------SPTTVTSS-------- 422

  Fly   449 ARGGTPIKRAKWHLGIRSQSKPNDIMLEVYRAMKALSYEWKIINP--------YHVRVRRQNVKT 505
                  ::.:.:|    |.::.|..|....:...|:|   :..:|        |..|.|     :
  Fly   423 ------VRSSSYH----SPTRCNSPMSSAQQQANAIS---RPSSPAAGTRHSTYGDRDR-----S 469

  Fly   506 GKFSKMSLQLYQVDAKSYLLDFKSLTNDEVEQGDDVIME------------SLTP--PPLSVSGV 556
            |..|.:|........||...|...:....:|:.|.:..|            .:.|  |..:.||.
  Fly   470 GHHSSVSRTPSHSSQKSIEGDVVVVREPRIERRDSLRQERGGGSPRDRGDCGIPPGSPGGNSSGS 534

  Fly   557 MPLQPTGHH 565
            ....|:.||
  Fly   535 TSASPSVHH 543

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AMPKalpha	NP_477313.1	STKc_AMPK_alpha	25..280	CDD:270981	130/262 (50%)
		UBA_AID_AMPKalpha	297..360	CDD:270521	15/69 (22%)
		AMPKA_C	457..580	CDD:213378	26/131 (20%)
sff	NP_648814.3	STKc_BRSK1_2	16..269	CDD:270983	129/253 (51%)
		S_TKc	18..269	CDD:214567	128/251 (51%)
		UBA_BRSK	298..350	CDD:270525	12/56 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45461630
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24343
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940