Protein Alignment AMPKalpha and CG8485

DIOPT Version :9

• Sequence 1: NP_477313.1
• Gene: AMPKalpha / 43904
• FlyBaseID: FBgn0023169
• Length: 582
• Species: Drosophila melanogaster
• Sequence 2: NP_610942.2
• Gene: CG8485 / 36579
• FlyBaseID: FBgn0033915
• Length: 860
• Species: Drosophila melanogaster
• Alignment Length: 566
• Identity: 169/566 - (29%)
• Similarity: 263/566 - (46%)
• Gaps: 93/566 - (16%)

  Fly    26 GHYLLGATLGTGTFGKVKIGEHQITRVKVAVKILNRQKIKSLDVVGK--IRREIQNLKLFRHPHI 88
            |.|.|..|||:|.|..||:..|..|..|||||::::.|   ||.|.|  :.:|::.:||.:||::
  Fly    18 GLYDLEETLGSGHFAVVKLARHVFTGAKVAVKVVDKTK---LDDVSKAHLFQEVRCMKLVQHPNV 79

  Fly    89 IKLYQVISTPSDIFMIMEYVSGGELFDYIVKHGK-LQEHQARRFFQQIISGVDYCHRHMIVHRDL 152
            ::||:||.|.:.:::::|...||:|:|||:||.. |.|..||::|:||:..:.|||:..:|||||
  Fly    80 VRLYEVIDTQTKLYLVLELGDGGDLYDYIMKHDSGLSEELARKYFRQILRAITYCHQLHVVHRDL 144

  Fly   153 KPENLLLDHNMH-VKIADFGLSNMMLDGEFLRTSCGSPNYAAPEVISGKLYAGPEVDIWSCGVIL 216
            ||||::....:. ||:.|||.||..|.|:.|.|.|||..|:|||::.|..|..|.|||||.||||
  Fly   145 KPENVVFFEKLGLVKLTDFGFSNKFLPGQKLETFCGSLAYSAPEILLGDSYDAPAVDIWSLGVIL 209

  Fly   217 YALLCGTLPFD---DEHVPTLFRKIKSGIFPIPEYLNKQVVNLVCQMLQVDPLKRANIEEIKKHE 278
            |.|:||..||:   |....|:....|   :.:|.:::....:|:..||..||.|||.:|||....
  Fly   210 YMLVCGQAPFEKANDSETLTMIMDCK---YTVPSHVSTDCRDLIASMLVRDPKKRATVEEIASSA 271

  Fly   279 WFQK-DLP-------AYLFPSSIEQDSNVIDTYAVAEVCTKFGVKETEVHNSLLSGDPHDQLAIA 335
            |.:. |.|       .:..|....:.....|...:.:......:...|.....|..:.::.:...
  Fly   272 WLKPIDEPDSTTSTSEHFLPLVSREQLGEEDHAFIIQKMINGNIASKEEILQALDKNKYNHITAT 336

  Fly   336 YHLIID------------NKRFADDAANQINEINNFFVAGSPPPPPPPPVPQSSMDHQAPLATVT 388
            |.|:.:            .:|..:||:.::.:.:...|    |..|.|...|.
  Fly   337 YFLLAELRLRRRREELAQKQRLLNDASMKVGDASRKLV----PEKPSPTEAQK------------ 385

  Fly   389 VGGGTSASSGTATPVPPVA--GGTPSSTIPIRPHPERIAPMRDRQLAMSVQTSGGG-----AFPE 446
              ||...|. ..||....|  ||.|..    |.....|....|.:.:.:..|:.|.     :...
  Fly   386 --GGVPISI-NVTPAAQFANDGGKPDK----RSRKCSIVREEDEEESATECTAVGNELKVTSSSR 443

  Fly   447 KTARGGTPIKRAKWHLGIRSQSKP-NDIMLEVYRAMKALSYEWKIIN---PYHVRVRRQNVKTGK 507
            :.|...:|..|:   :..||.|:| |....|            :|.|   |.|.|.:   :....
  Fly   444 REAFSDSPFSRS---IHERSSSEPGNQTKGE------------QIANSGVPSHSRTK---IVVSV 490

  Fly   508 FSKMSLQLYQVDAKSYLLDFKSLTN-DEVEQGDDVIMESLTPPPLS 552
            .:.::.:|.|:: ||..:|..:|:. .|:|.|      .|.|.|.|
  Fly   491 DATLAHKLKQME-KSAKIDEDTLSGLKELEIG------KLKPLPSS 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AMPKalpha	NP_477313.1	STKc_AMPK_alpha	25..280	CDD:270981	111/260 (43%)
		UBA_AID_AMPKalpha	297..360	CDD:270521	8/74 (11%)
		AMPKA_C	457..580	CDD:213378	25/101 (25%)
CG8485	NP_610942.2	STKc_SNRK	16..273	CDD:270976	111/260 (43%)
		S_TKc	20..273	CDD:214567	110/258 (43%)
		UBA_SNRK	296..338	CDD:270524	3/41 (7%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45461626
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24343
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940