Protein Alignment AMPKalpha and C27D6.11

DIOPT Version :10

• Sequence 1: NP_477313.1
• Gene: AMPKalpha / 43904
• FlyBaseID: FBgn0023169
• Length: 582
• Species: Drosophila melanogaster
• Sequence 2: NP_001364716.1
• Gene: C27D6.11 / 3564833
• WormBaseID: WBGene00044388
• Length: 331
• Species: Caenorhabditis elegans
• Alignment Length: 268
• Identity: 98/268 - (36%)
• Similarity: 151/268 - (56%)
• Gaps: 19/268 - (7%)

  Fly    34 LGTGTFGKVKIGEHQITRVKVAVKILN----RQKIKSLDVVGK-IRREIQNLKLFRHPHIIKLYQ 93
            ||:|::.:|........:::||.|::|    |:|.   |.:.| :.||.:.:||.:|.:|.:||:
 Worm    42 LGSGSYSRVARATWGDKKLEVAAKVINITSTREKD---DYIKKFLPREKEIVKLLKHDNICRLYE 103

  Fly    94 VISTPSDIFMIMEYVSGGELFDYIVKHGKLQEHQARRFFQQIISGVDYCHRHMIVHRDLKPENLL 158
            :||.|..|..:.|:.:||:|...:.....:.|..|:..|:|.|:.:.:...:.|||||||.||:.
 Worm   104 MISFPDHIIFVTEFCAGGDLLRKMKDIKTMNEDDAKFTFRQFIAALMHLQSYNIVHRDLKCENIF 168

  Fly   159 LDHNMHVKIADFGLSNMMLDGEFLRTSCGSPNYAAPEVISGKLYAGPEVDIWSCGVILYALLCGT 223
            ||.:.:||:.|||.|.::..||...|.|||..|.|||::.|:.|:|..||:||.|||||.:|.|:
 Worm   169 LDKHENVKLGDFGFSRILKPGEKSGTFCGSRAYVAPEILRGREYSGNAVDVWSTGVILYIMLVGS 233

  Fly   224 LPFDDEHVPT------LFRKIKSGIFPIPEYLNKQVVNLVCQMLQVDPLKRANIEEIKKHEWFQK 282
            :||||.: ||      |..|||   ||.....:.|...|:.::||.....|...:.|.:.||. |
 Worm   234 MPFDDRN-PTKMIERQLAHKIK---FPKLCTASVQSKALILEILQPHAPNRPTYKAICESEWL-K 293

  Fly   283 DLPAYLFP 290
            ..|.|:.|
 Worm   294 SQPYYMKP 301

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AMPKalpha	NP_477313.1	STKc_AMPK_alpha	25..280	CDD:270981	93/256 (36%)
		UBA_AID_AMPKalpha	297..360	CDD:270521
		AMPKA_C	457..580	CDD:213378
C27D6.11	NP_001364716.1	Protein Kinases, catalytic domain	38..292	CDD:473864	93/256 (36%)