Protein Alignment AMPKalpha and CG4629

DIOPT Version :10

• Sequence 1: NP_477313.1
• Gene: AMPKalpha / 43904
• FlyBaseID: FBgn0023169
• Length: 582
• Species: Drosophila melanogaster
• Sequence 2: NP_608564.3
• Gene: CG4629 / 33284
• FlyBaseID: FBgn0031299
• Length: 570
• Species: Drosophila melanogaster
• Alignment Length: 542
• Identity: 141/542 - (26%)
• Similarity: 234/542 - (43%)
• Gaps: 102/542 - (18%)

  Fly    24 KIGHYLLGATLGTGTFGKVKIGEHQITRVKVAVKILNRQKIKSLD--VVGKIRREIQNLKLFRHP 86
            :||.|.....:|.|.|.|||:..||:||.|||:|:::..: ..||  .:..:..||..|:...||
  Fly    62 RIGLYRFCGDIGRGNFSKVKLAVHQLTRDKVAIKVVDLDR-AGLDAKALRMLSSEIATLECVHHP 125

  Fly    87 HIIKLYQVISTPSDIFMIMEYVSGGELFDYIVKHGKLQEHQARRFFQQIISGVDYCHRHMIVHRD 151
            :|::|::|:.|...::::.|::.||||:::|.:.|.|:|..|....:|::..|.:.|....||||
  Fly   126 NILRLFEVVETLGRVYLVTEWIRGGELYNHITQGGPLREIHAAPLLKQLLLAVKHMHSLGYVHRD 190

  Fly   152 LKPENLLLDHNMHVKIADFGLSNMMLDG--EFLRTSCGSPNYAAPEVISGKLYAGPEVDIWSCGV 214
            :|.||:||.....:|:||||.|..:::|  :.|.|.||||.|||||:.|...|.|..||:|:.|:
  Fly   191 IKAENVLLLSEDRLKLADFGFSTQLINGANQKLDTFCGSPPYAAPELFSDDHYIGAPVDVWALGI 255

  Fly   215 ILYALLCGTLPFDDEHVPTLFRKIKSGIFPIPEYLNKQVVNLVCQMLQVDPLKRANIEEIKKHEW 279
            :||.::.|.:||....:|.|...|..|.:.:|..|:...:.|:.::|...|.:|..|:::...::
  Fly   256 LLYFMVVGNMPFRAPTIPGLKAAILKGDYLLPGQLSLPCIRLIQRILIHIPAQRPTIDDMLNSQF 320

  Fly   280 FQ-KDLPAYLFPSSIEQDSNVIDTYAVAEVCTKFGVKETEVHNSLLSGDPHDQLA--IAYHLIID 341
            .. ..|.|.|....|.|.:..:..       :.|.|: ::.|....|....|:.|  :....|..
  Fly   321 VTCPKLSADLMQWEINQHTKPVKR-------SIFWVR-SKSHRLRKSASLRDRYAEVVKKPAISM 377

  Fly   342 NKRFADDAANQINEINNFFVAGSPPPPPPPPVPQSSMDHQAPLATVTVGGGTSASSGTATPVPPV 406
            |.|..|:..     :.||.          .|:   .|.|:   ..|.|.........|.....|.
  Fly   378 NTRQQDEMF-----VQNFL----------QPI---EMGHE---LLVPVSSQLKEPQSTEQAKRPT 421

  Fly   407 -----AGGTPSSTIPIRPHPERIAPMRDRQLAMSVQTSGGG--------------AFPEKTARGG 452
                 .|.......|:...||       :|||...|:.|..              .|....|..|
  Fly   422 RRYMFCGSLKKKVTPMETEPE-------KQLANGGQSIGSAKINPWNVEVAEDCPLFKNYDAETG 479

  Fly   453 TPI-------------------KRAKWHLGIRS-------QSKPNDIMLEVYRAMKALSYEWKII 491
            :.:                   ::....||:.|       ||.|...::..||.         ::
  Fly   480 SCVMLPTNTEDLSQLGALEFEARQILAELGLTSEMLINARQSGPRSDIIGAYRI---------VV 535

  Fly   492 NPYHVRVRRQNVKTGKFSKMSL 513
            |    |:::|:....|..:|:|
  Fly   536 N----RLQKQSWLARKHVEMAL 553

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AMPKalpha	NP_477313.1	STKc_AMPK_alpha	25..280	CDD:270981	91/258 (35%)
		UBA_AID_AMPKalpha	297..360	CDD:270521	11/64 (17%)
		AMPKA_C	457..580	CDD:213378	14/64 (22%)
CG4629	NP_608564.3	STKc_NIM1	63..321	CDD:270977	91/258 (35%)