Protein Alignment AMPKalpha and LOC3291504

DIOPT Version :10

• Sequence 1: NP_477313.1
• Gene: AMPKalpha / 43904
• FlyBaseID: FBgn0023169
• Length: 582
• Species: Drosophila melanogaster
• Sequence 2: XP_061514913.1
• Gene: LOC3291504 / 3291504
• VectorBaseID: AGAMI1_015110
• Length: 1418
• Species: Anopheles gambiae
• Alignment Length: 620
• Identity: 184/620 - (29%)
• Similarity: 271/620 - (43%)
• Gaps: 116/620 - (18%)

  Fly    25 IGHYLLGATLGTGTFGKVKIGEHQITRVKVAVKILNRQKI--KSLDVVGKIRREIQNLKLFRHPH 87
            ||.|.|..|:|.|.|.|||:.:|..|..:||:||:::.::  .||.   |:.||::.:|:..||:
Mosquito   485 IGKYKLLKTIGKGNFAKVKLAKHVPTNKEVAIKIIDKTQLNPSSLQ---KLYREVRIMKMLDHPN 546

  Fly    88 IIKLYQVISTPSDIFMIMEYVSGGELFDYIVKHGKLQEHQARRFFQQIISGVDYCHRHMIVHRDL 152
            |:||:|||.|...::::|||.||||:|||:|.|||::|.:||..|:||:|.|.|||:..|:||||
Mosquito   547 IVKLFQVIETEKTLYLVMEYASGGEVFDYLVAHGKMKEKEARAKFRQIVSAVQYCHQKRIIHRDL 611

  Fly   153 KPENLLLDHNMHVKIADFGLSNMMLDGEFLRTSCGSPNYAAPEVISGKLYAGPEVDIWSCGVILY 217
            |.||||||..|::||||||.||....|..|.|.||||.|||||:..|:.|.|||||:||.|||||
Mosquito   612 KAENLLLDSEMNIKIADFGFSNEFTPGSKLDTFCGSPPYAAPELFQGRKYDGPEVDVWSLGVILY 676

  Fly   218 ALLCGTLPFDDEHVPTLFRKIKSGIFPIPEYLNKQVVNLVCQMLQVDPLKRANIEEIKKHEWF-- 280
            .|:.|:||||...:..|..::..|.:.||.|::.....|:.:.|.::|.||||:|.|.|.:|.
Mosquito   677 TLVSGSLPFDGATLKELRERVLRGKYRIPFYMSTDCEVLLKKFLVLNPSKRANLETIMKDKWMNM 741

  Fly   281 ---QKDLPAYLFPSSIEQDSNVI---DTYAV----AEVCTKFGVKETEVHNSLLSGDPHDQLAIA 335
               ..:|..|:.|....:|...|   ...||    .:.....|....::.:| |:...:|.:...
Mosquito   742 GYEDDELKPYVEPLPDLKDQKRIGKTGNQAVFKPRLKALVAMGYNRQDIEDS-LANTMYDDVFAT 805

  Fly   336 YHLI--------IDNKRFADDAANQINEINNFFVAGSPPPPPP--------------PPV----- 373
            |.|:        .|..|.....:.:....|....||:.....|              .|.
Mosquito   806 YLLLGRKSTDSESDGSRSGSSLSLRNIAGNEGAAAGNSQVQSPTHRGVHRSISASSTKPSRRASS 870

  Fly   374 ----------------PQSSMDHQAPLATVTVGGG--------------TSASSGTATPVPPVAG 408
                            |.:::...|..|.|..|||              .:|:.|.|.....|.|
Mosquito   871 GGETLQIFQRFITGVGPTTAVAAAAAAAAVGAGGGGVGGGGGGGAVVGSMAAAGGGAGTGTVVGG 935

  Fly   409 GTPSSTIPIRPHPERIAPMRDRQLAMSVQTSGGGA---------FPEKTARGGTPIKRAKWHLGI 464
            ||...|..:..:........:.  :.....|||||         |..:.......||.....|..
Mosquito   936 GTGGGTANVTGNSVLAGATNNH--SSGTGGSGGGASERTSISSNFKRQNTIDSATIKENTARLAA 998

  Fly   465 RSQSKPNDIMLEVYRAMKALSYEWKIINPYHVRVRRQNVKT---------------GKFSKMSLQ 514
            ::|...:.|...:.....:     .|.:|...|....:..|               |...:.|..
Mosquito   999 QNQRPASSITKPITSVDNS-----SISSPAKARTTSSSTSTKYDPSNGSRTVGPSAGLMPRRSTT 1058

  Fly   515 LYQVDAKSYLLDFKSLTNDEVEQGDDVIMESLTPP 549
            ||:          |:.:.::.....|....|...|
Mosquito  1059 LYE----------KTSSTEKTNSTTDPTSNSFVAP 1083

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AMPKalpha	NP_477313.1	STKc_AMPK_alpha	25..280	CDD:270981	125/256 (49%)
		UBA_AID_AMPKalpha	297..360	CDD:270521	12/77 (16%)
		AMPKA_C	457..580	CDD:213378	15/108 (14%)
LOC3291504	XP_061514913.1	None