Protein Alignment AMPKalpha and Trib2

DIOPT Version :10

• Sequence 1: NP_477313.1
• Gene: AMPKalpha / 43904
• FlyBaseID: FBgn0023169
• Length: 582
• Species: Drosophila melanogaster
• Sequence 2: NP_001101485.2
• Gene: Trib2 / 313974
• RGDID: 1564451
• Length: 343
• Species: Rattus norvegicus
• Alignment Length: 353
• Identity: 90/353 - (25%)
• Similarity: 139/353 - (39%)
• Gaps: 87/353 - (24%)

  Fly    47 HQITRVKVAVKILNRQKIKSLDVVGKIRR-----------------EIQNLK------------- 81
            |:.|.:.:|....:|.|.:..:.:..||.                 |..||.
  Rat     4 HRSTPITIARYGRSRNKTQDFEELSSIRSAEPSQSFSPNLGSPSPPETPNLSHCVSCIGKYLLLE 68

  Fly    82 ------LFRHPHI------------IKLYQ-------VISTPSDIFMIMEYVSG----------- 110
                  :||..|:            |..||       .:|..|:|..|.|.:.|
  Rat    69 PLEGDHVFRAVHLHSGEELVCKVFEISCYQESLAPCFCLSAHSNINQITEILLGETKAYVFFERS 133

  Fly   111 -GELFDYIVKHGKLQEHQARRFFQQIISGVDYCHRHMIVHRDLKPENLLLDHNMHVKIADFGLSN 174
             |::..::....||:|.:|.|.|.||.|.|.:||...:|.||||....:.......::....|.:
  Rat   134 YGDMHSFVRTCKKLREEEAARLFYQIASAVAHCHDGGLVLRDLKLRKFIFKDEERTRVKLESLED 198

  Fly   175 MML---DGEFLRTSCGSPNYAAPEVI-SGKLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLF 235
            ..:   |.:.|....|.|.|.:||:: :...|:|...|:||.||:||.:|.|..||.|....:||
  Rat   199 AYILRGDDDSLSDKHGCPAYVSPEILNTNGSYSGKAADVWSLGVMLYTMLVGRYPFHDIEPSSLF 263

  Fly   236 RKIKSGIFPIPEYLNKQVVNLVCQMLQVDPLKRANIEEIKKHEWFQKDLPAYLFPSSIEQDSNVI 300
            .||:.|.|.|||.|:.:...|:..:|:.:|.:|...:||..|.||..|...          ||
  Rat   264 SKIRRGQFNIPETLSPKAKCLIRSILRREPSERLTSQEILDHPWFSTDFSV----------SN-- 316

  Fly   301 DTYAVAEVCTKFGVKETEVHNSLLSGDP 328
            ..:...|.|.:. |.:..:..:|   ||
  Rat   317 SGFGAKEACDQL-VPDVNMEENL---DP 340

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AMPKalpha	NP_477313.1	STKc_AMPK_alpha	25..280	CDD:270981	79/303 (26%)
		UBA_AID_AMPKalpha	297..360	CDD:270521	8/32 (25%)
		AMPKA_C	457..580	CDD:213378
Trib2	NP_001101485.2	PK_TRB2	67..308	CDD:270924	69/240 (29%)