DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AMPKalpha and Tssk3

DIOPT Version :9

Sequence 1:	NP_477313.1	Gene:	AMPKalpha / 43904	FlyBaseID:	FBgn0023169	Length:	582	Species:	Drosophila melanogaster
Sequence 2:	NP_001007651.1	Gene:	Tssk3 / 297891	RGDID:	1359231	Length:	268	Species:	Rattus norvegicus

Alignment Length:	256	Identity:	91/256 - (35%)
Similarity:	154/256 - (60%)	Gaps:	5/256 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 YLLGATLGTGTFGKVKIGEHQITRVKVAVKILNRQKIKSLDVVGKIRREIQNLKLFRHPHIIKLY 92
            |.||.|:|.||:.|||....:..:.|||:||:::.......:...:.||:|.::...|.:||::|
  Rat    10 YQLGKTIGEGTYSKVKEAFSKKHQRKVAIKIIDKMGGPEEFIQRFLPRELQIVRTLDHKNIIRVY 74

  Fly    93 QVI-STPSDIFMIMEYVSGGELFDYIVKHGKLQEHQARRFFQQIISGVDYCHRHMIVHRDLKPEN 156
            ::: |....|:::||...||::||.::..|.|.|.:|:..|:|::..:.|||...:.|||||.||
  Rat    75 EMLESADGKIYLVMELAEGGDVFDCVLNGGPLPESRAKALFRQMVEAIRYCHGCGVAHRDLKCEN 139

  Fly   157 LLLDHNMHVKIADFGLSNMMLDG--EFLRTSCGSPNYAAPEVISGKLYAGPEVDIWSCGVILYAL 219
            .|| ...::|:.|||.:.::...  |..:|.|||..||||||:.|..:...:.|:||.||:||.:
  Rat   140 ALL-QGFNLKLTDFGFAKVLPKSRRELSQTFCGSTAYAAPEVLQGIPHDSKKGDVWSMGVVLYVM 203

  Fly   220 LCGTLPFDDEHVPTLFRKIKSGI-FPIPEYLNKQVVNLVCQMLQVDPLKRANIEEIKKHEW 279
            ||.:|||||..:|.:..:.:.|: ||....::.:..:|:.::|:.|.:.|.:|||:..|.|
  Rat   204 LCASLPFDDTDIPKMLWQQQKGVSFPTHLGISTECQDLLKRLLEPDMILRPSIEEVSWHPW 264

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AMPKalpha	NP_477313.1	STKc_AMPK_alpha	25..280	CDD:270981	91/256 (36%)
		UBA_AID_AMPKalpha	297..360	CDD:270521
		AMPKA_C	457..580	CDD:213378
Tssk3	NP_001007651.1	STKc_TSSK3-like	9..265	CDD:271065	91/256 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910