Protein Alignment AMPKalpha and Smok2a

DIOPT Version :9

• Sequence 1: NP_477313.1
• Gene: AMPKalpha / 43904
• FlyBaseID: FBgn0023169
• Length: 582
• Species: Drosophila melanogaster
• Sequence 2: NP_001178548.2
• Gene: Smok2a / 292316
• RGDID: 1565233
• Length: 501
• Species: Rattus norvegicus
• Alignment Length: 489
• Identity: 143/489 - (29%)
• Similarity: 223/489 - (45%)
• Gaps: 88/489 - (17%)

  Fly    28 YLLGATLGTGTFGKVKIGEHQITRVKVAVKILNRQKIKSLDVVGKIRREIQNLKLFRHPHIIKLY 92
            ||:..|:|.|....||:..|::|...||||:|    :|......::..|::.:....||:|:.|.
  Rat    27 YLVLNTIGHGFHAAVKLAVHRLTGTPVAVKML----LKRQQWCQQVTSEVEIMMRINHPNIVSLI 87

  Fly    93 QVISTPSDIFMIMEYVSGGELFDYIVKHGKLQEHQARRFFQQIISGVDYCHRHMIVHRDLKPENL 157
            |||.|....::|||...|.:|:.:|.:.|.|||.:||..|:|::|.|.|||...|:||||||:||
  Rat    88 QVIDTEKITYLIMELAKGNQLYSHIKEAGHLQEDEARGIFRQLLSAVGYCHEEGIIHRDLKPDNL 152

  Fly   158 LLDHNMHVKIADFGLSNMMLDGEFLRTSCGSPNYAAPEVISGKLYAGPEVDIWSCGVILYALLCG 222
            |:|....:||.|||.:..:..|:.|||..|:..::|||::.||.|.||:||:|:.|||||.:..|
  Rat   153 LVDTKGRIKIIDFGSATQVRPGQKLRTPYGTYAFSAPELLLGKFYEGPKVDVWALGVILYYMTVG 217

  Fly   223 TLPFDDEHVPTLFRKIKSGIFPIPEYLNKQVVNLVCQMLQVDPLKRANIEEIKKHEWFQKDLPAY 287
            .:||:...:|.|.|:|..|.:.:|..|::::.:|:..:|:|:..:|..|.::..|.|.:.|...
  Rat   218 KVPFEAASIPLLRRQIVLGTYVVPPGLSEELQDLLSLLLKVNSQQRPTIPDLLTHPWLKIDSEG- 281

  Fly   288 LFPSSIEQDSNVIDTYAVAEVCTKFGVKETEVHNSLLSGDPHDQLAIAYHLIIDNKRFADDAA-- 350
             ||...::...:....|:.......|.:..||.:||                 |.|:|....|
  Rat   282 -FPQPCKELIPLRPDPAILRAMQDIGFEAQEVKDSL-----------------DQKKFNQSMACY 328

  Fly   351 -----NQINEINNFFVAGSPPPPPPPPVPQSSMDHQAPLATVTVGGGTSASSGTATPVPPVAGGT 410
                 ..:.|.:|      |..|.|...|..::|:.|    .:|.|..|..|
  Rat   329 YLLEKQALQECDN------PTRPHPCMTPFPTLDYPA----TSVRGLRSRGS------------- 370

  Fly   411 PSSTIPIRPHPERIAPMRDRQLAMSVQTSGGGAFPEKTARGGTP----IKRAKWHLGIRSQSKPN 471
                             ..|.|..|..:.|...       |.||    :|||.|..|:  ..:|.
  Rat   371 -----------------EPRWLGSSSDSQGSDL-------GQTPSHRLVKRASWPGGL--LCRPR 409

  Fly   472 DIMLEVYRAMKALSYEWKIINPYHVRVRRQNVKT 505
            .|...|     .|::...|.:|....|..:..||
  Rat   410 QIAPTV-----ELTHRISISDPCFSSVHSRGKKT 438

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AMPKalpha	NP_477313.1	STKc_AMPK_alpha	25..280	CDD:270981	96/251 (38%)
		UBA_AID_AMPKalpha	297..360	CDD:270521	12/69 (17%)
		AMPKA_C	457..580	CDD:213378	13/49 (27%)
Smok2a	NP_001178548.2	STKc_AMPK-like	26..274	CDD:270905	96/250 (38%)
		UBA_MARK_Par1	294..333	CDD:270522	10/55 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24343
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010