DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AMPKalpha and Tssk6

DIOPT Version :9

Sequence 1:	NP_477313.1	Gene:	AMPKalpha / 43904	FlyBaseID:	FBgn0023169	Length:	582	Species:	Drosophila melanogaster
Sequence 2:	NP_001099548.1	Gene:	Tssk6 / 290670	RGDID:	1559764	Length:	273	Species:	Rattus norvegicus

Alignment Length:	269	Identity:	92/269 - (34%)
Similarity:	153/269 - (56%)	Gaps:	7/269 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 NGQPLVKIGHYLLGATLGTGTFGKVKIGEHQITRVKVAVKILNRQKIKSLDVVGK-IRREIQNLK 81
            :|..|:....|.||.|:|.|::.|||:...:..:..||:|:::|::... |.|.| :.||:..|:
  Rat     2 SGDKLLSELGYKLGRTIGEGSYSKVKVATSKKYKGTVAIKVVDRRRAPP-DFVNKFLPRELSILR 65

  Fly    82 LFRHPHIIKLYQVIST-PSDIFMIMEYVSGGELFDYIVKHGKLQEHQARRFFQQIISGVDYCHRH 145
            ..|||||:.:::.|.. ...::::|| .:..:|...:.::|::...|||..|.||...|.|.|.|
  Rat    66 GVRHPHIVHVFEFIEVCNGKLYIVME-AAATDLLQAVQRNGRIPGSQARELFSQIAGAVRYLHDH 129

  Fly   146 MIVHRDLKPENLLLD-HNMHVKIADFGLSNMMLDGEFLRTS-CGSPNYAAPEVISGKLYAGPEVD 208
            .:||||||.||:||. ....||:.|||..........|.|: |||..||:|||:.|..|...:.|
  Rat   130 HLVHRDLKCENVLLSPDERRVKLTDFGFGRQAHGYPDLSTTYCGSAAYASPEVLLGIPYDPKKYD 194

  Fly   209 IWSCGVILYALLCGTLPFDDEHVPTLFRKIKSGI-FPIPEYLNKQVVNLVCQMLQVDPLKRANIE 272
            :||.||:||.::.|.:||||..:..|.|:.|.|: :|....|:::..:|:.::||..|..|.:..
  Rat   195 VWSLGVVLYVMVTGCMPFDDSDIAGLPRRQKRGVLYPDGLELSERCKSLIAELLQFSPSARPSAG 259

  Fly   273 EIKKHEWFQ 281
            ::.::.|.:
  Rat   260 QVARNGWLR 268

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AMPKalpha	NP_477313.1	STKc_AMPK_alpha	25..280	CDD:270981	89/259 (34%)
		UBA_AID_AMPKalpha	297..360	CDD:270521
		AMPKA_C	457..580	CDD:213378
Tssk6	NP_001099548.1	STKc_TSSK6-like	11..267	CDD:271066	89/257 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910