Protein Alignment AMPKalpha and kin1

DIOPT Version :9

• Sequence 1: NP_477313.1
• Gene: AMPKalpha / 43904
• FlyBaseID: FBgn0023169
• Length: 582
• Species: Drosophila melanogaster
• Sequence 2: NP_596106.1
• Gene: kin1 / 2540792
• PomBaseID: SPBC4F6.06
• Length: 891
• Species: Schizosaccharomyces pombe
• Alignment Length: 650
• Identity: 187/650 - (28%)
• Similarity: 284/650 - (43%)
• Gaps: 156/650 - (24%)

  Fly    16 SANGQPLVK---IGHYLLGATLGTGTFGKVKIGEHQITRVKVAVKILNR---------------- 61
            ||:.:|..:   ||:|:||.|:|.|:.||||:..|..|..:.|:||:.|
pombe   110 SADEKPRERRKVIGNYVLGKTIGAGSMGKVKVAHHLKTGEQFAIKIVTRLHPDITKAKAAASAEA 174

  Fly    62 ------QKIKSLDVVGKIRREIQNLKLFRHPHIIKLYQVISTPSDIFMIMEYVSGGELFDYIVKH 120
                  :|.|.:..|    ||.....|.|||:|.:...|..|.|..:|:.|:|.||::.|||:.|
pombe   175 TKAAQSEKNKEIRTV----REAALSTLLRHPYICEARDVYITNSHYYMVFEFVDGGQMLDYIISH 235

  Fly   121 GKLQEHQARRFFQQIISGVDYCHRHMIVHRDLKPENLLLDHNMHVKIADFGLSNMMLDGEFLRTS 185
            |||:|.|||:|.:||.|.:.|.|::.:||||||.||:|:.....:||.||||||:......|||.
pombe   236 GKLKEKQARKFVRQIGSALSYLHQNSVVHRDLKIENILISKTGDIKIIDFGLSNLYRRQSRLRTF 300

  Fly   186 CGSPNYAAPEVISGKLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFRKIKSGIFPIPEYLN 250
            |||..:||||:::.:.|.|||||:||.|::||.|:||.:||||:::..|..|||.|....|.||:
pombe   301 CGSLYFAAPELLNAQPYIGPEVDVWSFGIVLYVLVCGKVPFDDQNMSALHAKIKKGTVEYPSYLS 365

  Fly   251 KQVVNLVCQMLQVDPLKRANIEEIKKHEWFQKDL---PAYLFPSS-------------------- 292
            .....|:.:||..||||||.:||:..|.|..::.   ||...|..
pombe   366 SDCKGLLSRMLVTDPLKRATLEEVLNHPWMIRNYEGPPASFAPERSPITLPLDPEIIREMNGFDF 430

  Fly   293 ------IEQDSNVIDTYAVAEVCT-----------------KFGVKET--EVHNSLL-----SGD 327
                  :.:.:.||.:.|...:..                 :|.::..  ::.|.:|     :.|
pombe   431 GPPEKIVRELTKVISSEAYQSLAKTGFYSGPNSADKKKSFFEFRIRHAAHDIENPILPSLSMNTD 495

  Fly   328 PHDQL--AIAYHLIIDNKRFADDAANQINEINNFFVAGSPPP-----------PPPPPVPQSSMD 379
            .:|..  .|:.:.::..:|..:...|. |.|....|:..|..           ||.|.|.....|
pombe   496 IYDAFHPLISIYYLVSERRVYEKGGNW-NRIAKTPVSSVPSSPVQPTSYNRTLPPMPEVVAYKGD 559

  Fly   380 HQAPLATVTVGGGTSASSGTATPVPPVAGGTPSSTIPIRPHPERI---APMRDRQLAMSVQTSGG 441
            .::|    .|...||.:.....|.......:||:|..|:.:|..|   ...|.:|...|..|...
pombe   560 EESP----RVSRNTSLARRKPLPDTESHSPSPSATSSIKKNPSSIFRRFSSRRKQNKSSTSTLQI 620

  Fly   442 GAFPEKTARGGTPIKRAKWHLGIRSQSKPNDIMLEVYRAMKALSYEWKIINPYHVRVRRQNVKTG 506
            .| |.:|:: ..|..|.|      ...||            .:||:.|::....:. |..:|:.|
pombe   621 SA-PLETSQ-SPPTPRTK------PSHKP------------PVSYKNKLVTQSAIG-RSTSVREG 664

  Fly   507 KFSKMSLQLYQVDAKSYLLDFKSLTNDEVEQGDDVIMESLTP--------PPLSVSGVMPLQPTG 563
            :::.:|.|:                       |.:.|:|..|        || ||.....|.|.|
pombe   665 RYAGISSQM-----------------------DSLNMDSTGPSASNMANAPP-SVRNNRVLNPRG 705

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AMPKalpha	NP_477313.1	STKc_AMPK_alpha	25..280	CDD:270981	118/276 (43%)
		UBA_AID_AMPKalpha	297..360	CDD:270521	13/88 (15%)
		AMPKA_C	457..580	CDD:213378	22/114 (19%)
kin1	NP_596106.1	STKc_Kin1_2	123..395	CDD:270979	117/275 (43%)
		S_TKc	125..395	CDD:214567	116/273 (42%)
		MARK_C_like	753..889	CDD:213377

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910