Protein Alignment AMPKalpha and ppk27

DIOPT Version :10

• Sequence 1: NP_477313.1
• Gene: AMPKalpha / 43904
• FlyBaseID: FBgn0023169
• Length: 582
• Species: Drosophila melanogaster
• Sequence 2: NP_595405.1
• Gene: ppk27 / 2540313
• PomBaseID: SPBC337.04
• Length: 413
• Species: Schizosaccharomyces pombe
• Alignment Length: 265
• Identity: 81/265 - (30%)
• Similarity: 122/265 - (46%)
• Gaps: 61/265 - (23%)

  Fly    57 KILNRQKIKSLDVVGKIRREIQNLKLFRHPHIIKLYQVISTPSDIFMIMEYVSGGELFDYIVKHG 121
            |..|.:|.:    |...|:||..||...||.:::|.....:.:::.::..|..||:|:.|..||
pombe   140 KSQNEKKAR----VKVFRQEIWALKTLSHPCVVQLLNYYVSSAELILVENYCMGGDLYHYTKKH- 199

  Fly   122 KLQEHQ------ARRFFQQIISGVDYCHRHMIVHRDLKPENLLLDH---------------NMHV 165
                |.      ..|.|.:::..|.|.|...::|||||.||:||..               |..:
pombe   200 ----HSDFSLEFVGRIFSELVHTVAYLHSKCLIHRDLKLENILLTQPYNVIKTIDNWKNYPNALI 260

  Fly   166 KIADFGLSNMMLDGE--FLRTSCGSPNYAAPEVISGKLYAGPEVDIWSCGVILYALLCGTLPFDD 228
            :|:||.|| :.:|.:  .:::||||..||.|||..|..:.|...|.||.|::|:|||.|.||||.
pombe   261 QISDFELS-IFVDSKNHLVQSSCGSQEYAPPEVYMGIAHDGFRADAWSLGIVLFALLEGRLPFDS 324

  Fly   229 EHVPTLFRKIKSGIFPIPEYLNKQVVNLVCQMLQVD--------PLKRA--NIEEIKKHEW---- 279
              .|||          .||  |.::...|.::::.|        |.||:  |..:.....|
pombe   325 --YPTL----------DPE--NVRIKRYVQRLVRCDYTWHLCKSPFKRSTGNTNDNDDPSWRFRL 375

  Fly   280 FQKDL 284
            |.|.|
pombe   376 FVKKL 380

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AMPKalpha	NP_477313.1	STKc_AMPK_alpha	25..280	CDD:270981	78/259 (30%)
		UBA_AID_AMPKalpha	297..360	CDD:270521
		AMPKA_C	457..580	CDD:213378
ppk27	NP_595405.1	Protein Kinases, catalytic domain	144..396	CDD:473864	79/261 (30%)